Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Guillem, Plasencia"'
Autor:
Edith Said, Guillem Plasencia, Bryn D. Webb, Laura Castilla-Vallmanya, Daniel Grinberg, Bruce D. Gelb, Ulrich Brinkmann, Klaus Mayer, Roser Urreizti, Susanna Balcells, Neal Cody, Gilad D. Evrony
Publikováno v:
Eur J Hum Genet
DPH1 variants have been associated with an ultra-rare and severe neurodevelopmental disorder, mainly characterized by variable developmental delay, short stature, dysmorphic features, and sparse hair. We have identified four new patients (from two di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af65df32ed93337e4dfa079c912b9cc4
https://europepmc.org/articles/PMC6906407/
https://europepmc.org/articles/PMC6906407/
Autor:
Axel Pähler, Guillem Plasencia, Esra Nurten Cece-Esencan, Fabien Fontaine, Marieke Teppner, Andreas Brink, Ismael Zamora
Publikováno v:
SM Analytical and Bioanalytical Techniques. 1:1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aa2050be9cea49020a914195ef41707
https://doi.org/10.36876/smabt.1002
https://doi.org/10.36876/smabt.1002
Autor:
Guillem Plasencia, Fabien Fontaine, Axel Pähler, Marieke Teppner, Esra Nurten Cece-Esencan, Ismael Zamora, Andreas Brink
Publikováno v:
Rapid Communications in Mass Spectrometry. 30:301-310
Rationale Cytochrome P450 (CYP450) reaction phenotyping (CRP) and kinetic studies are essential in early drug discovery to determine which metabolic enzymes react with new drug entities. A new semi-automated computer-assisted workflow for CRP is intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::077b950cd19f780236e7162c47a46679
https://doi.org/10.1002/rcm.7429
https://doi.org/10.1002/rcm.7429
Autor:
Roser Urreizti, Klaus Mayer, Gilad D. Evrony, Edith Said, Laura Castilla-Vallmanya, Neal A. L. Cody, Guillem Plasencia, Bruce D. Gelb, Daniel Grinberg, Ulrich Brinkmann, Bryn D. Webb, Susanna Balcells
Publikováno v:
European Journal of Human Genetics. 28:138-138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dac031d84c13ab025af6707105c3490
https://doi.org/10.1038/s41431-019-0394-5
https://doi.org/10.1038/s41431-019-0394-5
Autor:
Esra Nurten, Cece-Esencan, Fabien, Fontaine, Guillem, Plasencia, Marieke, Teppner, Andreas, Brink, Axel, Pähler, Ismael, Zamora
Publikováno v:
Rapid communications in mass spectrometry : RCM. 30(2)
Cytochrome P450 (CYP450) reaction phenotyping (CRP) and kinetic studies are essential in early drug discovery to determine which metabolic enzymes react with new drug entities. A new semi-automated computer-assisted workflow for CRP is introduced in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d35f15f6533ba6c8669a678106f2fc08
https://pubmed.ncbi.nlm.nih.gov/26689160
https://pubmed.ncbi.nlm.nih.gov/26689160
Autor:
Adolf Graessmann, Fausto G. Hegardt, Dolors Serra, Guillermina Asins, Guillem Plasencia, Carles Codony, Montserrat Bach-Elias, Concha Caudevilla, Ruth Román
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus-Elsevier
instname
Scopus-Elsevier
Carnitine octanoyltransferase (COT) produces three different transcripts in rat through cis- and trans-splicing reactions, which may lead to the synthesis of two proteins. Generation of the three COT transcripts in rat does not depend on sex, develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dea5559fe8865abae5c22737b456d5e
https://doi.org/10.1093/nar/29.14.3108
https://doi.org/10.1093/nar/29.14.3108
Publikováno v:
Drug discovery today. Technologies. 10(1)
One of the key factors in drug discovery is related to the metabolic properties of the lead compound, which may influence the bioavailability of the drug, its therapeutic window, and unwanted side-effects of its metabolites. Therefore, it is of criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4be97e8188b7883e845a18e0701fd74
https://pubmed.ncbi.nlm.nih.gov/24050248
https://pubmed.ncbi.nlm.nih.gov/24050248
Publikováno v:
ChemMedChem. 4(3)
A new method for fragment and scaffold replacement is presented that generates new families of compounds with biological activity, using GRID molecular interaction fields (MIFs) and the crystal structure of the targets. In contrast to virtual screeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1759e233b161faaa307a383e14e8babd
https://pubmed.ncbi.nlm.nih.gov/19152365
https://pubmed.ncbi.nlm.nih.gov/19152365
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Drug Metabolism Reviews. Nov2015 Supplement, Vol. 47, p41-297. 257p.