The hypothalamic link between arousal and sleep homeostasis in mice

Autor: Yamagata, T, Kahn, MC, Prius-Mengual, J, Meijer, E, Šabanović, M, Guillaumin, MCC, van der Vinne, V, Huang, Y-G, McKillop, LE, Jagannath, A, Peirson, SN, Mann, EO, Foster, RG, Vyazovskiy, VV

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Our current understanding of how sleep is regulated is based upon the model of sleep homeostasis, which defines a variable called Process S as a measure of sleep need, and a so-called “flip-flop” model of state switching, which build

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df2ce54d4ef53308055410727580ddb
https://doi.org/10.1073/pnas.2101580118

The role of the hypothalamus in cortical arousal and sleep homeostasis

Autor: Aarti Jagannath, Guillaumin Mcc., T Yamagata, Huang Y-G., Vladyslav V. Vyazovskiy, L E McKillop, Edward O. Mann, Vincent van der Vinne, Stuart N. Peirson, M Šabanović, Russell G. Foster, M C Kahn

Sleep and wakefulness are not simple homogenous all-or-none states, but instead are characterized by rich dynamics of brain activity across many temporal and spatial scales. Rapid global state transitions between waking and sleeping are believed to b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d921ee708350e8b09c7de32d01f45b76
https://doi.org/10.1101/2020.05.19.104521

Somnotate: A probabilistic sleep stage classifier for studying vigilance state transitions.

Autor: Brodersen PJN; Department of Pharmacology, University of Oxford; Mansfield Road, Oxford, United Kingdom., Alfonsa H; Department of Pharmacology, University of Oxford; Mansfield Road, Oxford, United Kingdom., Krone LB; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Blanco-Duque C; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Fisk AS; Nuffield Department of Clinical Neurosciences, University of Oxford; John Radcliffe Hospital, Oxford, United Kingdom., Flaherty SJ; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Guillaumin MCC; Nuffield Department of Clinical Neurosciences, University of Oxford; John Radcliffe Hospital, Oxford, United Kingdom.; Sleep and Circadian Neuroscience Institute, University of Oxford; Oxford, United Kingdom.; Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich; Schwerzenbach, Switzerland., Huang YG; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Kahn MC; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., McKillop LE; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Milinski L; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Taylor L; Nuffield Department of Clinical Neurosciences, University of Oxford; John Radcliffe Hospital, Oxford, United Kingdom., Thomas CW; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Yamagata T; Nuffield Department of Clinical Neurosciences, University of Oxford; John Radcliffe Hospital, Oxford, United Kingdom., Foster RG; Sleep and Circadian Neuroscience Institute, University of Oxford; Oxford, United Kingdom., Vyazovskiy VV; Department of Physiology, Anatomy and Genetics, University of Oxford; Parks Road, United Kingdom., Akerman CJ; Department of Pharmacology, University of Oxford; Mansfield Road, Oxford, United Kingdom.

Publikováno v: PLoS computational biology [PLoS Comput Biol] 2024 Jan 17; Vol. 20 (1), pp. e1011793. Date of Electronic Publication: 2024 Jan 17 (Print Publication: 2024).

Something to Snack on: Can Dietary Modulators Boost Mind and Body?

Autor: Guillaumin MCC; Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zürich, 8603 Schwerzenbach, Switzerland., Syarov B; Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zürich, 8603 Schwerzenbach, Switzerland., Burdakov D; Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zürich, 8603 Schwerzenbach, Switzerland., Peleg-Raibstein D; Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zürich, 8603 Schwerzenbach, Switzerland.

Publikováno v: Nutrients [Nutrients] 2023 Mar 10; Vol. 15 (6). Date of Electronic Publication: 2023 Mar 10.

Detection of neuronal OFF periods as low amplitude neural activity segments.

Autor: Harding CD; Department of Physiology Anatomy and Genetics, Sir Jules Thorn Sleep and Circadian Neuroscience Institute, University of Oxford, Oxford, UK. christian.harding@sjc.ox.ac.uk.; The Kavli Institute for Nanoscience Discovery, Oxford, UK. christian.harding@sjc.ox.ac.uk., Guillaumin MCC; Nuffield Department of Clinical Neurosciences, Sir Jules Thorn Sleep and Circadian Neuroscience Institute, University of Oxford, Oxford, UK.; Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zürich, Schwerzenbach, Switzerland., Krone LB; Department of Physiology Anatomy and Genetics, Sir Jules Thorn Sleep and Circadian Neuroscience Institute, University of Oxford, Oxford, UK.; University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.; Centre for Experimental Neurology, University of Bern, Bern, Switzerland., Kahn MC; Department of Physiology Anatomy and Genetics, Sir Jules Thorn Sleep and Circadian Neuroscience Institute, University of Oxford, Oxford, UK.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, USA., Blanco-Duque C; Department of Physiology Anatomy and Genetics, Sir Jules Thorn Sleep and Circadian Neuroscience Institute, University of Oxford, Oxford, UK.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, USA., Mikutta C; Department of Physiology Anatomy and Genetics, Sir Jules Thorn Sleep and Circadian Neuroscience Institute, University of Oxford, Oxford, UK.; Translational Research Center, University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.; Private Clinic Meiringen, Meiringen, Switzerland., Vyazovskiy VV; Department of Physiology Anatomy and Genetics, Sir Jules Thorn Sleep and Circadian Neuroscience Institute, University of Oxford, Oxford, UK.; The Kavli Institute for Nanoscience Discovery, Oxford, UK.

Publikováno v: BMC neuroscience [BMC Neurosci] 2023 Feb 21; Vol. 24 (1), pp. 13. Date of Electronic Publication: 2023 Feb 21.