Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Guillaume de Lartigue"'
Autor:
Jiyoung S. Kim, Kevin C. Williams, Rebecca A. Kirkland, Ruth Schade, Kimberly G. Freeman, Carolina R. Cawthon, Allison W. Rautmann, Jessica M. Smith, Gaylen L. Edwards, Travis C. Glenn, Philip V. Holmes, Guillaume de Lartigue, Claire B. de La Serre
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101764- (2023)
Objective: Our goal is to investigate if microbiota composition modulates reward signaling and assess the role of the vagus in mediating microbiota to brain communication. Methods: Male germ-free Fisher rats were colonized with gastrointestinal conte
Externí odkaz:
https://doaj.org/article/7f5736eaabbd4f44b879eb736ead372d
Publikováno v:
Nutrients, Vol 15, Iss 11, p 2472 (2023)
Metformin, a frontline therapy for type 2 diabetes and related metabolic diseases, results in variable outcomes. This study aimed to investigate whether sweetened beverages (caloric or non-caloric) affect the therapeutic benefits of metformin on gluc
Externí odkaz:
https://doaj.org/article/f998b915da9840e0936ddd5fe495c369
Autor:
Samira Mansouri, Himanshu Gogoi, Seema Patel, Divya S. Katikaneni, Arashdeep Singh, Alexandra Aybar-Torres, Guillaume de Lartigue, Lei Jin
Publikováno v:
J Immunol
MPYS/STING (stimulator of IFN genes) senses cyclic dinucleotides (CDNs), generates type I IFNs, and plays a critical role in infection, inflammation, and cancer. In this study, analyzing genotype and haplotype data from the 1000 Genomes Project, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbad1efe55a03aaf457e26fb7946fc74
https://doi.org/10.4049/jimmunol.2200158
https://doi.org/10.4049/jimmunol.2200158
Publikováno v:
Frontiers in Human Neuroscience, Vol 14 (2020)
Recently a role for the vagus nerve in conditioning food preferences was established in rodents. In a prospective controlled clinical trial in humans, invasive vagus nerve stimulation shifted food choice toward lower fat content. Here we explored whe
Externí odkaz:
https://doaj.org/article/21b1d55381c34f3fbbeb4325311115de
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Gastrointestinal (GI) vagal afferents convey sensory signals from the GI tract to the brain. Numerous subtypes of GI vagal afferent have been identified but their individual roles in gut function and feeding regulation are unclear. In the past decade
Externí odkaz:
https://doaj.org/article/f681135448d048fb97df22c20658326e
Autor:
Shin J. Lee, Jean-Philippe Krieger, Macarena Vergara, Danielle Quinn, Molly McDougle, Alan de Araujo, Rebecca Darling, Benjamin Zollinger, Seth Anderson, Annabeth Pan, Emilie J. Simonnet, Angelica Pignalosa, Myrtha Arnold, Arashdeep Singh, Wolfgang Langhans, Helen E. Raybould, Guillaume de Lartigue
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 2028-2039.e4 (2020)
Summary: The vagus nerve conveys gastrointestinal cues to the brain to control eating behavior. In obesity, vagally mediated gut-brain signaling is disrupted. Here, we show that the cocaine- and amphetamine-regulated transcript (CART) is a neuropepti
Externí odkaz:
https://doaj.org/article/9028c48d5a25491e9e34b4ebda7ac0fc
Autor:
Andrea N. Suarez, Ted M. Hsu, Clarissa M. Liu, Emily E. Noble, Alyssa M. Cortella, Emily M. Nakamoto, Joel D. Hahn, Guillaume de Lartigue, Scott E. Kanoski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Feeding-relevant vagal signaling occurs between the gastrointestinal tract and the brain, but it is unclear if this pathway influences cognitive processes. This study shows that endogenous gastrointestinal derived vagal sensory signaling promotes hip
Externí odkaz:
https://doaj.org/article/947b95883c294462a5f1802c459ec8ad
Autor:
Alan Moreira de Araujo, Isadora Braga, Gabriel Leme, Arashdeep Singh, Molly McDougle, Justin Smith, Macarena Vergara, Mingxing Yang, M Lin, H Khoshbouei, Eric Krause, Andre G de Oliveira, Guillaume de Lartigue
We investigated the lateralization of gut-innervating vagal sensory neurons and their roles in feeding behavior. Using genetic, anatomical, and behavioral analyses, we discovered a subset of highly lateralized vagal sensory neurons with distinct sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27bcb3109687d9e4cd5158ea5355fb22
https://doi.org/10.1101/2023.05.08.539627
https://doi.org/10.1101/2023.05.08.539627
Autor:
Molly McDougle, Alan de Araujo, Macarena Vergara, Mingxin Yang, Arashdeep Singh, Isadora Braga, Nikhil Urs, Brandon Warren, Guillaume de Lartigue
Food is a powerful natural reinforcer that guides feeding decisions. The vagus nerve conveys internal sensory information from the gut to the brain about nutritional value; however, the cellular and molecular basis of macronutrient-specific reward ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf5f08fe1c7403a4d31ec0739a74ad9f
https://doi.org/10.1101/2022.08.09.503218
https://doi.org/10.1101/2022.08.09.503218
Autor:
Mingxin Yang, Guillaume De Lartigue
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b234b07a3b4512ff218f7425dc1a43b3
https://doi.org/10.1096/fasebj.2022.36.s1.r2338
https://doi.org/10.1096/fasebj.2022.36.s1.r2338