Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Guillaume Viault"'
Autor:
Gabriele Möller, Veronika Temml, Antonio Cala Peralta, Océane Gruet, Pascal Richomme, Denis Séraphin, Guillaume Viault, Luisa Kraus, Petra Huber-Cantonati, Elisabeth Schopfhauser, Johanna Pachmayr, Janina Tokarz, Daniela Schuster, Jean-Jacques Helesbeux, Kenneth Allen Dyar
Publikováno v:
Metabolites, Vol 12, Iss 2, p 99 (2022)
Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and prel
Externí odkaz:
https://doaj.org/article/2ab68851bb2c41d1830b279e836dcadf
Autor:
Helmut Pein, Alexia Ville, Simona Pace, Veronika Temml, Ulrike Garscha, Martin Raasch, Khaled Alsabil, Guillaume Viault, Chau-Phi Dinh, David Guilet, Fabiana Troisi, Konstantin Neukirch, Stefanie König, Rosella Bilancia, Birgit Waltenberger, Hermann Stuppner, Maria Wallert, Stefan Lorkowski, Christina Weinigel, Silke Rummler, Marc Birringer, Fiorentina Roviezzo, Lidia Sautebin, Jean-Jacques Helesbeux, Denis Séraphin, Alexander S. Mosig, Daniela Schuster, Antonietta Rossi, Pascal Richomme, Oliver Werz, Andreas Koeberle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Vitamin E metabolites are proposed to have signalling capacity, but how they may regulate immune responses is still unclear. Here the authors show that a vitamin E metabolite, α-T-13′-COOH, can inhibit 5-lipoxygenase and thereby suppress the synth
Externí odkaz:
https://doaj.org/article/8f5b1e43017943509f14b4b68fe07ec5
Autor:
Rodolphe Perrot, Jean-Jacques Helesbeux, Denis Séraphin, Marie Kempf, Pascal Richomme, Khaled Alsabil, Guillaume Viault, Alexia Ville
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
New 5-substituted vitamin E derivatives were semisynthesized, and their antibacterial activity against human Gram-positive and Gram-negative pathogens was evaluated. Several vitamin E analogues were active against methicillin-resistant Staphylococcus
Autor:
Jimmy Josué Ceballos-Cruz, Jean-Jacques Hélesbeux, Guillaume Viault, Denis Séraphin, Gumersindo Mirón-López, Rubén M. Carballo, Pascal Richomme, Luis Manuel Peña-Rodríguez
Publikováno v:
Journal of the Mexican Chemical Society. 66
Chalcone-vitamin E hybrids 6’-O-tosyl-3,4,5-trimethoxy-δ-tocopherol-chalcone (1), 3,4,5-trimethoxy-δ-tocopherol-chalcone (2), 6’-O-tosyl-3,4,5-trimethoxy-δ-tocopherol-retrochalcone (3) and 3,4,5-trimethoxy-δ-tocopherol-retrochalcone (4) were
Autor:
Stephan Permann, Konstantin Neukirch, Jean-Jacques Helesbeux, Guillaume Viault, Chau-Phi Dinh, Elena Brunner, Oliver Werz, Denis Seraphin, Pascal Richomme, Andreas Koeberle
Publikováno v:
Planta Medica.
Autor:
Denis Séraphin, Christian Kretzer, Markus Werner, Pascal Richomme, Andreas Koeberle, Veronika Temml, Paul M. Jordan, Jean-Jacques Helesbeux, Daniela Schuster, Katharina P.L. Meyer, Robert Klaus Hofstetter, Guillaume Viault, Antonio Cala Peralta, Hermann Stuppner, Daniel Hoff, Oliver Werz
Publikováno v:
Biochemical pharmacology. 195
Specialized pro-resolving mediators (SPMs) comprise lipid mediators (LMs) produced from polyunsaturated fatty acids (PUFAs) via stereoselective oxygenation particularly involving 12/15-lipoxygenases (LOXs). In contrast to pro-inflammatory LMs such as
Autor:
Andreas Koeberle, Denis Séraphin, Stefan Lorkowski, Tiago Rodrigues, Oliver Werz, Daniela Schuster, Dimitri Bréard, Hermann Stuppner, Ida Cerqua, Antonietta Rossi, Simona Pace, Marta C. Marques, Alexander S. Mosig, Paul M. Jordan, Stephan Permann, Jana Gerstmeier, Martin Raasch, Gonçalo J. L. Bernardes, André Gollowitzer, Ulrike Garscha, Chau-Phi Dinh, Alexia Ville, Jean-Jacques Helesbeux, Fiorentina Roviezzo, Guillaume Viault, Elena Brunner, Pascal Richomme, Veronika Temml, Rossella Bilancia, Khaled Alsabil, Konstantin Loeser, Konstantin Neukirch
Publikováno v:
Journal of Medicinal Chemistry
Endogenous long-chain metabolites of vitamin E (LCMs) mediate immune functions by targeting 5-lipoxygenase (5-LOX) and increasing the systemic concentrations of resolvin E3, a specialized proresolving lipid mediator. SAR studies on semisynthesized an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197aa94407387a7b89fbecdcc110c28a
http://hdl.handle.net/11588/879642
http://hdl.handle.net/11588/879642
Autor:
Dong Tien Tran, Laëtitia Minder, Laurent Pouységu, Denis Deffieux, Elisabeth Génot, Yoan Capello, Carmelo Di Primo, Philippe A. Peixoto, Sofiane Dairi, Stéphane Quideau, Guillaume Viault, Daniela Melanie Delannoy López
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, In press, ⟨10.1002/chem.202005187⟩
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202005187⟩
Chemistry-A European Journal, In press, ⟨10.1002/chem.202005187⟩
Chemistry-A European Journal, Wiley-VCH Verlag, In press, ⟨10.1002/chem.202005187⟩
International audience; A selection of bioactive polyphenols of different structural classes, such as the ellagitannins vescalagin and vescalin, the flavanoids catechin, epicatechin, epigallocatechin gallate (EGCG), and procyanidin B2, and the stilbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf20b83a5d7603b8a70defcf679ce2e1
https://hal.science/hal-03374449
https://hal.science/hal-03374449
Autor:
Antoine, Bruguière, Séverine, Derbré, Joël, Dietsch, Jules, Leguy, Valentine, Rahier, Quentin, Pottier, Dimitri, Bréard, Sorphon, Suor-Cherer, Guillaume, Viault, Anne-Marie, Le Ray, Frédéric, Saubion, Pascal, Richomme
Publikováno v:
Analytical chemistry. 92(13)
Whether chemists or biologists, researchers dealing with metabolomics require tools to decipher complex mixtures. As a part of metabolomics and initially dedicated to identifying bioactive natural products, dereplication aims at reducing the usual ti
Autor:
Valentine Rahier, Dimitri Bréard, Pascal Richomme, Anne-Marie Le Ray, Séverine Derbré, Joël Dietsch, Antoine Bruguière, Quentin Pottier, Sorphon Suor-Cherer, Jules Leguy, Guillaume Viault, Frédéric Saubion
Publikováno v:
Analytical Chemistry
Analytical Chemistry, American Chemical Society, 2020, 92 (13), pp.8793-8801. ⟨10.1021/acs.analchem.0c00193⟩
Analytical Chemistry, American Chemical Society, 2020, 92 (13), pp.8793-8801. ⟨10.1021/acs.analchem.0c00193⟩
Whether chemists or biologists, researchers dealing with metabolomics require tools to decipher complex mixtures. As a part of metabolomics and initially dedicated to identifying bioactive natural ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbe8fedd6841973988ff683660ee0ec
https://hal.univ-angers.fr/hal-02862826
https://hal.univ-angers.fr/hal-02862826