Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Guillaume Urtecho"'
Autor:
Qian Wang, Yicheng Guo, Logan T. Schwanz, Ian A. Mellis, Yiwei Sun, Yiming Qu, Guillaume Urtecho, Riccardo Valdez, Emily Stoneman, Aubree Gordon, Harris H. Wang, David D. Ho, Lihong Liu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
As SARS-CoV-2 continues to spread and mutate, tracking the viral evolutionary trajectory and understanding the functional consequences of its mutations remain crucial. Here, we characterized the antibody evasion, ACE2 receptor engagement, and viral i
Externí odkaz:
https://doaj.org/article/abf1d75ad25541d9b5a79451cfd5d018
Autor:
Timothy C. Yu, Winnie L. Liu, Marcia S. Brinck, Jessica E. Davis, Jeremy Shek, Grace Bower, Tal Einav, Kimberly D. Insigne, Rob Phillips, Sriram Kosuri, Guillaume Urtecho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Precisely tuning the genetic response to environmental stimuli is a key step in engineering synthetic biology systems. Here, the authors profile 8269 IPTG-induced promoters to deconstruct the relationship between sequence architecture and gene expres
Externí odkaz:
https://doaj.org/article/4cab2046d5594f268114bd03aed9a468
Autor:
Guillaume Urtecho, Danielle E. Campbell, David M. Hershey, Fatima A. Hussain, Rachel J. Whitaker, George A. O’Toole
Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
ABSTRACT Bacteriophages have immense potential as antibiotic therapies and in genetic engineering. Understanding the mechanisms that bacteriophages implement to infect their hosts will allow researchers to manipulate these systems and adapt them to s
Externí odkaz:
https://doaj.org/article/9eee29da79544916bea4fc57ce355514
Autor:
Ilya Andreev, Kamilla M. E. Laidlaw, Simone M. Giovanetti, Guillaume Urtecho, Daniel Shriner, Joshua S. Bloom, Chris MacDonald, Meru J. Sadhu
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Secreted protein toxins are widely used weapons in conflicts between organisms. Elucidating how organisms genetically adapt to defend themselves against these toxins is fundamental to understanding the coevolutionary dynamics of competing organisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6777940d82eac69c270af43458f18632
https://doi.org/10.1073/pnas.2217194120
https://doi.org/10.1073/pnas.2217194120
Autor:
Guillaume Urtecho, Thomas Moody, Yiming Huang, Ravi U. Sheth, Miles Richardson, Opeyemi Lekan, Florencia Velez-Cortes, Deirdre Ricaurte, Harris H. Wang
Gastrointestinal colonization by commensal bacteria is a reproducible yet complex process. Mapping the spatiotemporal and genetic factors driving microbial colonization of the gut is key to understanding the gut microbiome and improving clinical inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a460f70265a5b3e0d2845785d869e2e
https://doi.org/10.1101/2022.10.21.513299
https://doi.org/10.1101/2022.10.21.513299
Autor:
Ilya Andreev, Simone M. Giovanetti, Guillaume Urtecho, Daniel Shriner, Joshua S. Bloom, Meru J. Sadhu
Secreted protein toxins are widely used weapons in conflicts between organisms. Killer yeast produce killer toxins that inhibit the growth of nearby sensitive yeast. We investigated variation in resistance to the killer toxin K28 across diverse natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c80d8442412e11a991ee2ef1cc6ec94
https://doi.org/10.1101/2021.10.25.465803
https://doi.org/10.1101/2021.10.25.465803
Autor:
Jessica E. Davis, Rob Phillips, Jeremy Shek, Timothy C. Yu, Winnie L. Liu, Marcia Brinck, Grace Bower, Guillaume Urtecho, Tal Einav, Sriram Kosuri, Kimberly D. Insigne
Publikováno v:
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
A crucial step towards engineering biological systems is the ability to precisely tune the genetic response to environmental stimuli. In the case of Escherichia coli inducible promoters, our incomplete understanding of the relationship between sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b324baceca2a7619aba7045e6b916dbf
http://europepmc.org/articles/PMC7804116
http://europepmc.org/articles/PMC7804116
Autor:
Rachel J. Whitaker, Guillaume Urtecho, Danielle E. Campbell, George A. O'Toole, Fatima A. Hussain, David M. Hershey
Publikováno v:
mSphere
mSphere, Vol 5, Iss 6 (2020)
mSphere, Vol 5, Iss 6 (2020)
Bacteriophages are useful nonantibiotic therapeutics for bacterial infections as well as threats to industries utilizing bacterial agents. This study identified Phaeobacter virus MD18, a phage antagonist of Phaeobacter inhibens, a bacterium with prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fb29673ef12b755b414b3275c22072
http://europepmc.org/articles/PMC7643831
http://europepmc.org/articles/PMC7643831
Autor:
Danielle E. Campbell, George A. O'Toole, David M. Hershey, Rachel J. Whitaker, Guillaume Urtecho
Bacteriophage technologies have immense potential as antibiotic therapies and in genetic engineering. Understanding the mechanisms that bacteriophages implement to infect their hosts will allow researchers to manipulate these systems and adapt them t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be43911ba595294e7987ed766e33707c
https://doi.org/10.1101/2020.04.13.038638
https://doi.org/10.1101/2020.04.13.038638
Autor:
Arielle D. Tripp, Tracey Chan, Sriram Kosuri, Nathan B. Lubock, Hwang-Beom Kim, Guillaume Urtecho, Marcia Brinck, Kimberly D. Insigne
SummaryDespite decades of intense genetic, biochemical, and evolutionary characterizations of bacterial promoters, we still lack the basic ability to identify or predict transcriptional activities of promoters using primary sequence. Even in simple,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea06ddff50f1f6bba07c0c2430ef2fa