Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Guillaume Stewart-Jones"'
Autor:
Roger Le Grand, Anders Fomsgaard, Marianne Jansson, Leo Heyndrickx, Gabriella Scarlatti, Priscilla Biswas, Guillaume Stewart-Jones, Emma Joanne Bowles, Nathalie Dereuddre-Bosquet, Frédéric Martinon, Rogier W Sanders, Mark Melchers, Tara Laura Elvang, Betina Skovgaard Andresen, Berit Grevstad, Johanna Repits, Marie Borggren, Lasse Vinner
Publikováno v:
Vaccines, Vol 1, Iss 3, Pp 305-327 (2013)
HIV-1 DNA vaccines have many advantageous features. Evaluation of HIV-1 vaccine candidates often starts in small animal models before macaque and human trials. Here, we selected and optimized DNA vaccine candidates through systematic testing in rabbi
Externí odkaz:
https://doaj.org/article/a2b7b1bb8b1d446496f7f69f5e152250
Autor:
Marcela V Maus, Jason Plotkin, Gopinadh Jakka, Guillaume Stewart-Jones, Isabelle Rivière, Taha Merghoub, Jedd Wolchok, Christoph Renner, Michel Sadelain
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
Chimeric antigen receptors (CARs) are synthetic receptors that usually redirect T cells to surface antigens independent of human leukocyte antigen (HLA). Here, we investigated a T cell receptor-like CAR based on an antibody that recognizes HLA-A*0201
Externí odkaz:
https://doaj.org/article/0fec421582a340cfbea2567b5dda0878
Autor:
Ema T Crooks, Tommy Tong, Bimal Chakrabarti, Kristin Narayan, Ivelin S Georgiev, Sergey Menis, Xiaoxing Huang, Daniel Kulp, Keiko Osawa, Janelle Muranaka, Guillaume Stewart-Jones, Joanne Destefano, Sijy O'Dell, Celia LaBranche, James E Robinson, David C Montefiori, Krisha McKee, Sean X Du, Nicole Doria-Rose, Peter D Kwong, John R Mascola, Ping Zhu, William R Schief, Richard T Wyatt, Robert G Whalen, James M Binley
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004932 (2015)
Eliciting broad tier 2 neutralizing antibodies (nAbs) is a major goal of HIV-1 vaccine research. Here we investigated the ability of native, membrane-expressed JR-FL Env trimers to elicit nAbs. Unusually potent nAb titers developed in 2 of 8 rabbits
Externí odkaz:
https://doaj.org/article/65b7f896418649c1899f642d72673ccb
Autor:
Leo Heyndrickx, Guillaume Stewart-Jones, Marianne Jansson, Hanneke Schuitemaker, Emma Bowles, Luigi Buonaguro, Berit Grevstad, Lasse Vinner, Katleen Vereecken, Joe Parker, Meghna Ramaswamy, Priscilla Biswas, Guido Vanham, Gabriella Scarlatti, Anders Fomsgaard, NGIN Consortium
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74552 (2013)
BACKGROUND: Ten to 30% of HIV-1 infected subjects develop broadly neutralizing antibodies (bNAbs) during chronic infection. We hypothesized that immunizing rabbits with viral envelope glycoproteins (Envs) from these patients may induce bNAbs, when fo
Externí odkaz:
https://doaj.org/article/37edf8c11d924b2381a98fc5660b5381
Autor:
Suzanne M. Scheaffer, Diana Lee, Bradley Whitener, Baoling Ying, Kai Wu, Chieh-Yu Liang, Hardik Jani, Philippa Martin, Nicholas J. Amato, Laura E. Avena, Daniela Montes Berrueta, Stephen D. Schmidt, Sijy O’Dell, Arshan Nasir, Gwo-Yu Chuang, Guillaume Stewart-Jones, Richard A. Koup, Nicole A. Doria-Rose, Andrea Carfi, Sayda M. Elbashir, Larissa B. Thackray, Darin K. Edwards, Michael S. Diamond
Publikováno v:
Nature Medicine. 29:247-257
Autor:
Alec W. Freyn, Caroline Atyeo, Patricia L. Earl, Jeffrey L. Americo, Gwo-Yu Chuang, Harini Natarajan, Tiffany Frey, Jason Gall, Juan I Moliva, Ruth Hunegnaw, Guha Asthagiri Arunkumar, Clinton Ogega, Arshan Nasir, Hamilton Bennett, Joshua Johnson, Michael A. Durney, Guillaume Stewart-Jones, Jay W Hooper, Tonya Colpitts, Galit Alter, Nancy J. Sullivan, Andrea Carfi, Bernard Moss
Monkeypox virus (MPXV) caused a global outbreak in 2022, fueled by behaviorally-altered and enhanced human-to-human transmission. While smallpox vaccines were rapidly deployed to curb spread and disease among those at highest risk, breakthrough disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4530621a23ef6dcac5c8f7cf2e7bd109
https://doi.org/10.1101/2022.12.17.520886
https://doi.org/10.1101/2022.12.17.520886
Autor:
Jessica Rubens, Jacqueline Brockhurst, Shristi Ghimire, Rebecca Loomis, Alexandrine Derrien-Colemyn, Jason Villano, Guillaume Stewart-Jones, Tracy Ruckwardt, Michael Watson, Barney S Graham, Diane Griffin
Publikováno v:
Open Forum Infectious Diseases. 9
Background Measles-Mumps-Rubella (MMR) is an effective live-virus vaccine against measles virus (MeV). However, use of MMR is limited by its inability to boost MeV immunity, lack of immunogenicity in infants, and contraindication in pregnant and immu
Autor:
Kai Wu, Carole Henry, Charis Palandjian, Sarah O’Connell, Angela Woods, Darin K. Edwards, Anna Hill, Hamilton Bennett, Naveen Nunna, Elisabeth Narayanan, Samantha Falcone, Matthew A. Koch, Andrea Carfi, Robert A. Seder, Diana Lee, Guillaume Stewart-Jones, LingZhi Ma, Barney S. Graham, Angela Choi, Tonya M. Colpitts, Kizzmekia S. Corbett, Adrian B. McDermott, Sayda Elbashir, Julian Quinones, Hardik Jani
Publikováno v:
bioRxiv
Vaccine
Vaccine
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of a global pandemic that has led to more than 2.8 million deaths worldwide. Safe and effective vaccines are now available, including Moderna’s COVID-19 vaccine (mR
Autor:
Suzanne M. Scheaffer, Diana Lee, Bradley Whitener, Baoling Ying, Kai Wu, Hardik Jani, Philippa Martin, Nicholas J. Amato, Laura E. Avena, Daniela Montes Berrueta, Stephen D. Schmidt, Sijy O’Dell, Arshan Nasir, Gwo-Yu Chuang, Guillaume Stewart-Jones, Richard A. Koup, Nicole A. Doria-Rose, Andrea Carfi, Sayda M. Elbashir, Larissa B. Thackray, Darin K. Edwards, Michael S. Diamond
Publikováno v:
bioRxiv
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) vaccine efficacy and persistent transmission. In this study, we evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53da2e914bcba0cdf9252d53319d90f4
https://doi.org/10.1101/2022.09.12.507614
https://doi.org/10.1101/2022.09.12.507614
Autor:
Yannic C. Bartsch, Xin Tong, Jaewon Kang, María José Avendaño, Eileen F. Serrano, Tamara García-Salum, Catalina Pardo-Roa, Arnoldo Riquelme, Yongfei Cai, Isabella Renzi, Guillaume Stewart-Jones, Bing Chen, Rafael A. Medina, Galit Alter
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
The Omicron variant of SARS-CoV-2 has been shown to evade neutralizing antibodies elicited by vaccination or infection. Despite the global spread of the Omicron variant, even among highly vaccinated populations, death rates have not increased concomi