Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Guillaume Sarrabayrouse"'
Autor:
Alain E. Andrea, Andrada Chiron, Guillaume Sarrabayrouse, Stéphanie Bessoles, Salima Hacein-Bey-Abina
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In recent years, following the groundbreaking achievements of chimeric antigen receptor (CAR) T cell therapy in hematological cancers, and advancements in cell engineering technologies, the exploration of other immune cells has garnered significant a
Externí odkaz:
https://doaj.org/article/aa1b8a2a8ddf4e649776d6b5e057e544
Autor:
Alain E. Andrea, Andrada Chiron, Sarah Mallah, Stéphanie Bessoles, Guillaume Sarrabayrouse, Salima Hacein-Bey-Abina
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
During this last decade, adoptive transfer of T lymphocytes genetically modified to express chimeric antigen receptors (CARs) emerged as a valuable therapeutic strategy in hematological cancers. However, this immunotherapy has demonstrated limited ef
Externí odkaz:
https://doaj.org/article/bc0b3529ba29475f88a47269a5c030e7
Autor:
Marina Lleal, Guillaume Sarrabayrouse, Joseane Willamil, Alba Santiago, Marta Pozuelo, Chaysavanh Manichanh
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 630-641 (2019)
Background: Faecal microbiota transplantation (FMT) is a novel potential therapy for inflammatory bowel diseases, but it is poorly characterised. Methods: We evaluated the performance of the mouse and rat as a pre-clinical model for human microbiota
Externí odkaz:
https://doaj.org/article/75fca3b8fade43a6b8678b6989baf74a
Autor:
Guillaume Sarrabayrouse, Stefania Landolfi, Marta Pozuelo, Joseane Willamil, Encarna Varela, Allison Clark, David Campos, Claudia Herrera, Alba Santiago, Kathleen Machiels, Severine Vermeire, Marc Martí, Eloy Espin, Chaysavanh Manichanh
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
Background: The remission of Crohn's disease (CD) can be accomplished by faecal microbiota transplantation (FMT). However, this procedure has a low success rate, which could be attributed to mis-communication between recipient intestinal mucosa and d
Externí odkaz:
https://doaj.org/article/0bab2b017661424daa293fcfeaffcbb5
Autor:
Alba Santiago, Elisabet Sanchez, Allison Clark, Marta Pozuelo, Miguel Calvo, Francisca Yañez, Guillaume Sarrabayrouse, Lidia Perea, Silvia Vidal, Alberto Gallardo, Carlos Guarner, German Soriano, Chaysavanh Manichanh
Publikováno v:
mSystems, Vol 4, Iss 1 (2019)
ABSTRACT Whether the interaction between the gut microbiota and the immune response influences the evolution of cirrhosis is poorly understood. We aimed to investigate modifications of the microbiome and the immune response during the progression of
Externí odkaz:
https://doaj.org/article/82dccdf260864021bb4ad70b84f43f33
Autor:
Joudy Alameddine, Emmanuelle Godefroy, Loukas Papargyris, Guillaume Sarrabayrouse, Julie Tabiasco, Chantal Bridonneau, Karina Yazdanbakhsh, Harry Sokol, Frédéric Altare, Francine Jotereau
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The human colonic mucosa contains regulatory type 1-like (Tr1-like, i.e., IL-10-secreting and Foxp3-negative) T cells specific for the gut Clostridium Faecalibacterium prausnitzii (F. prausnitzii), which are both decreased in Crohn's disease patients
Externí odkaz:
https://doaj.org/article/965c431d2981440a85f391e9e3d77668
Autor:
Christine Pich, Iotefa Teiti, Guillaume Sarrabayrouse, Franck Gallardo, Rémi Gence, Anne-Françoise Tilkin-Mariamé
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148095 (2016)
CD70 is a costimulatory molecule member of the Tumor Necrosis Factor family that is expressed on activated immune cells. Its ectopic expression has been described in several types of cancer cells including lymphomas, renal cell carcinomas and gliobla
Externí odkaz:
https://doaj.org/article/9b4c4d44fa3646d18a3f4b3467ea27dd
Autor:
Guillaume Sarrabayrouse, Cindy Synaeve, Kevin Leveque, Gilles Favre, Anne-Françoise Tilkin-Manamé
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 12, Pp 1078-1090 (2007)
The capacity of FasL molecules expressed on melanoma cells to induce lymphocyte apoptosis contributes to either antitumor immune response or escape depending on their expression level. Little is known, however, about the mechanisms regulating FasL pr
Externí odkaz:
https://doaj.org/article/553fd08354d247e5944e5007decc815e
Autor:
Guillaume Sarrabayrouse, Céline Bossard, Joe-Marc Chauvin, Anne Jarry, Guillaume Meurette, Elodie Quévrain, Chantal Bridonneau, Laurence Preisser, Karim Asehnoune, Nathalie Labarrière, Frédéric Altare, Harry Sokol, Francine Jotereau
Publikováno v:
PLoS Biology, Vol 12, Iss 4, p e1001833 (2014)
How the microbiota affects health and disease is a crucial question. In mice, gut Clostridium bacteria are potent inducers of colonic interleukin (IL)-10-producing Foxp3 regulatory T cells (Treg), which play key roles in the prevention of colitis and
Externí odkaz:
https://doaj.org/article/9c8384521d34434aa5d7daca284ee34d
Autor:
Guillaume Sarrabayrouse, Christine Pich, Raphaël Moriez, Virginie Armand-Labit, Philippe Rochaix, Gilles Favre, Anne-Françoise Tilkin-Mariamé
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9043 (2010)
BACKGROUND: Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens (MHC-I) and costimulatory molecules. We have previously shown that geranylgeranyl transferase i
Externí odkaz:
https://doaj.org/article/046a61634843414f8027d66d54213291