Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Guillaume Roy-Proulx"'
Publikováno v:
Biology of Blood and Marrow Transplantation. 11(4):260-271
When presented alone, H7a and HY antigens elicit CD8 T-cell responses of similar amplitude, but H7a totally abrogates the response to HY when both antigens are presented on the same antigen-presenting cell. We found that H7a- and HY-specific T-cell p
Autor:
Denis-Claude Roy, Pierre Fontaine, Claude Perreault, Laurent Knafo, Chantal Baron, Guillaume Roy-Proulx
Publikováno v:
Nature Medicine. 7:789-794
Adoptive transfer of T cells reactive to minor histocompatibility antigens has the unmatched ability to eradicate malignant hematopoietic cells. Unfortunately, its use is hampered by the associated graft-versus-host disease. The critical issue of a p
Autor:
Guillaume Roy-Proulx, Marianne M. Martinic, Claude Perreault, Rolf M. Zinkernagel, Gwladys Gérard, Marie-Ève Blais
Publikováno v:
Blood. 103(8)
If present in sufficient numbers, could extrathymic T cells substitute for thymus-derived T cells? To address this issue, we studied extrathymic T cells that develop in athymic mice under the influence of oncostatin M (OM). In this model, extensive T
Publikováno v:
Blood. 101(2)
Adoptive transfer of allogeneic T cells has unmatched efficacy to eradicate leukemic cells. We therefore sought to evaluate in kinetic terms interactions between T cells and allogeneic leukemic cells. T cells primed against the model B6dom1 minor his
Autor:
Marie-Christine Meunier, Guillaume Roy-Proulx, Anne-Marie Lanteigne, Claude Perreault, Sylvie Brochu
Publikováno v:
European journal of immunology. 31(8)
The presence of dominant epitopes suppresses generation of CTL activity toward other non-dominant epitopes found on the same antigen-presenting cell (APC). This phenomenon, termed immunodomination, drastically restricts the diversity of the repertoir