Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Guillaume Poissonnet"'
Publikováno v:
ACS Omega, Vol 5, Iss 42, Pp 27591-27606 (2020)
Externí odkaz:
https://doaj.org/article/2236469ca48441e6a2f6f5ef289bfa52
Autor:
Catherine Dacquet, Yvonne Westermaier, Isabelle Theret, Pierre Ducrot, Xavier Barril, Perron-Sierra Françoise, Guillaume Poissonnet, Sergio Ruiz-Carmona, Jean A. Boutin
Publikováno v:
Journal of computer-aided molecular design. 31(8)
The knowledge of the free energy of binding of small molecules to a macromolecular target is crucial in drug design as is the ability to predict the functional consequences of binding. We highlight how a molecular dynamics (MD)-based approach can be
Autor:
Guillaume Poissonnet
Publikováno v:
Synthetic Communications. 27:3839-3846
Various substituted 1,2-benzoxazoles were prepared with good yields from salicylaldoximes and orthohydroxyphenylketoximes via intramolecular Mitsunobu reaction.
Publikováno v:
The Journal of Organic Chemistry. 61:2273-2282
Treatment of norharman with (trimethylsilyl)methyl triflate in dichloromethane gave 2-N-[(trimethylsilyl)methyl]-β-carboline triflate (10). The latter reacted with diethyl acetylenedicarboxylate (11a) or ethyl propiolate (11b) in the presence of ces
Publikováno v:
ChemInform. 27
Treatment of norharman with (trimethylsilyl)methyl triflate in dichloromethane gave 2-N-[(trimethylsilyl)methyl]-β-carboline triflate (10). The latter reacted with diethyl acetylenedicarboxylate (11a) or ethyl propiolate (11b) in the presence of ces
Autor:
Guillaume Le Baut, Larbi Belachmi, Massimo Sabatini, Jacqueline Bonnet, Guillaume Poissonnet, Jean-Daniel Brion
Publikováno v:
ChemInform. 31
Publikováno v:
ChemInform. 33
Short and convenient syntheses of 5-trifluoromethyltryptamine and 5-trifluoromethyltryptophole have been realized via a regioselective, palladium catalyzed, coupling/annulation method involving functionalized alkynes and 2-iodo-4-trifluoromethylanili
Autor:
Guillaume Poissonnet, Robert H. Dodd, Bruno Pfeiffer, Stéphane Léonce, Georges H. Werner, Pierre Renard, Martial Bertrand, Christiane Gaspard, Marie-Hélène Théret-Bettiol
Publikováno v:
Bioorganicmedicinal chemistry. 9(8)
A series of 1-cyano and 2-cyanohexahydroindolizino[8,7-b]indole derivatives was prepared by 1,3-dipolar cycloaddition of acrylonitrile with ylides derived from 3,4-dihydro-beta-carboline and its 6-methoxy, 6-benzyloxy, 9-methyl and 9-benzyl analogues
Autor:
Adrian Newman-Tancredi, Millan Mark, Guillaume Poissonnet, Solo Goldstein, Yann Quentric, Nathalie Carpentier, Jean-Gilles Parmentier, Didier Cussac
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 365(3)
Employing a novel, rapid and sensitive method for evaluation of phospholipase C (PLC) activity, the present study characterized the actions of diverse agonists and antagonists at human (h)5-HT2C receptors expressed in Chinese Hamster Ovary (CHO) cell
Publikováno v:
ChemInform. 21