Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Guillaume P, Nicolas"'
Autor:
Ivana Bratic Hench, Luca Roma, Floriana Conticelli, Lenard Bubendorf, Byron Calgua, Clémentine Le Magnen, Salvatore Piscuoglio, Mark A. Rubin, Alin Chirindel, Guillaume P. Nicolas, Tatjana Vlajnic, Tobias Zellweger, Arnoud J. Templeton, Frank Stenner, Christian Ruiz, Cyrill Rentsch, Lukas Bubendorf
Publikováno v:
Cancers, Vol 16, Iss 1, p 45 (2023)
Most men with prostate cancer (PCa), despite potentially curable localized disease at initial diagnosis, progress to metastatic disease. Despite numerous treatment options, choosing the optimal treatment for individual patients remains challenging. B
Externí odkaz:
https://doaj.org/article/bad39937c4cc4a99a63b94715549f0a0
Autor:
Rosalba Mansi, Karim Abid, Guillaume P. Nicolas, Luigi Del Pozzo, Eric Grouzmann, Melpomeni Fani
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background Somatostatin receptor (SST) targeting, specifically of the subtype 2 (SST2), with radiolabeled somatostatin analogs, is established for imaging and treatment of neuroendocrine tumors. Owing to the concomitant and heterogeneous exp
Externí odkaz:
https://doaj.org/article/4dc9844c52274a5393ea58285478f33d
Publikováno v:
Cancers, Vol 14, Iss 5, p 1172 (2022)
Somatostatin receptors (SSTs) are recognized as favorable molecular targets in neuroendocrine tumors (NETs) and neuroendocrine neoplasms (NENs), with subtype 2 (SST2) being the predominantly and most frequently expressed. PET/CT imaging with 68Ga-lab
Externí odkaz:
https://doaj.org/article/fcf5d13cdcc248dbb14cb23d5cac6b2f
Autor:
Mairene Coto-Llerena, Caner Ercan, Venkatesh Kancherla, Stephanie Taha-Mehlitz, Serenella Eppenberger-Castori, Savas D. Soysal, Charlotte K. Y. Ng, Martin Bolli, Markus von Flüe, Guillaume P. Nicolas, Luigi M. Terracciano, Melpomeni Fani, Salvatore Piscuoglio
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Fibroblast activation protein α (FAP) plays an important role in tissue remodeling and helps tumor cells invade surrounding tissue. We sought to investigate FAP as a prognostic molecular marker in colorectal cancer (CRC) using immunohistochemical an
Externí odkaz:
https://doaj.org/article/6f5808a753d44eb9a73ade37bf98aac5
Autor:
Keelara Abiraj, Samer Ursillo, Maria Luisa Tamma, Svetlana N. Rylova, Beatrice Waser, Edwin C. Constable, Melpomeni Fani, Guillaume P. Nicolas, Jean Claude Reubi, Helmut R. Maecke
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background Somatostatin receptor targeting radiopeptides are successfully being used to image, stage, and monitor patients with neuroendocrine tumours. They are exclusively agonists that internalise upon binding to the relevant receptor. Acc
Externí odkaz:
https://doaj.org/article/3e6f8fdce56940b8921dfb43b004e7dc
Autor:
Deborah Theiler, Marco Cattaneo, Lawrence O. Dierickx, Peter Igaz, Simona Grozinsky-Glasberg, Claire Bournaud, Thomas O’Dorisio, M. Sue O’Dorisio, Damian Wild, Emanuel Christ, Guillaume P. Nicolas
Publikováno v:
Cancers, Vol 13, Iss 24, p 6290 (2021)
Peptide receptor radionuclide therapy (PRRT) is a well-established treatment in somatostatin receptor-expressing neuroendocrine tumours (NETs). The safety and efficacy of PRRT in >79 years old patients (EP) have not been systematically investigated.
Externí odkaz:
https://doaj.org/article/cb6718ba731442daa613a542fa4bd513
The Emergence of Somatostatin Antagonist–Based Theranostics: Paving the Road Toward Another Success?
Publikováno v:
Journal of Nuclear Medicine. 64:682-684
Publikováno v:
Swiss Medical Weekly, Vol 148, Iss 4546 (2018)
BACKGROUND Important causes of endogenous hyperinsulinaemic hypoglycaemia (EHH) in adult patients are insulinoma and adult nesidioblastosis. Data on main symptoms in EHH are scarce and controversial. We analysed main symptoms of patients with EHH in
Externí odkaz:
https://doaj.org/article/228c735d2bb649da9259d77db5860a0b
Autor:
Rosalba Mansi, Guillaume Pierre Nicolas, Luigi Del Pozzo, Karim Alexandre Abid, Eric Grouzmann, Melpomeni Fani
Publikováno v:
Molecules, Vol 25, Iss 18, p 4155 (2020)
Targeted radionuclide therapy of somatostatin receptor (SST)-expressing tumors is only partially addressed by the established somatostatin analogs having an affinity for the SST subtype 2 (SST2). Aiming to target a broader spectrum of tumors, we eval
Externí odkaz:
https://doaj.org/article/0e80f5a36a2f4aa092cf15a6bad392d6
Autor:
Julie, Refardt, Johannes, Hofland, Antwi, Kwadwo, Guillaume P, Nicolas, Christof, Rottenburger, Melpomeni, Fani, Damian, Wild, Emanuel, Christ
Publikováno v:
Reviews in endocrinemetabolic disorders. 22(3)
Neuroendocrine neoplasms (NENs) comprise a heterogeneous group of tumors, mainly localized in the gastrointestinal system. What characterizes NENs is the expression of hormone receptors on the tumor cell surface, making them accessible for diagnostic