Evaluation of CONSRANK-Like Scoring Functions for Rescoring Ensembles of Protein–Protein Docking Poses

Autor: Guillaume Launay, Masahito Ohue, Julia Prieto Santero, Yuri Matsuzaki, Cécile Hilpert, Nobuyuki Uchikoga, Takanori Hayashi, Juliette Martin

Publikováno v: Frontiers in Molecular Biosciences, Vol 7 (2020)

Scoring is a challenging step in protein–protein docking, where typically thousands of solutions are generated. In this study, we ought to investigate the contribution of consensus-rescoring, as introduced by Oliva et al. (2013) with the CONSRANK m

Externí odkaz: https://doaj.org/article/4886d2ccebee41869616303faf0a5b4a

Rational Prediction of PROTAC-compatible Protein-Protein Interfaces by Molecular Docking

Autor: Gilberto P. Pereira, Brian Jiménez-García, Riccardo Pellarin, Guillaume Launay, Sangwook Wu, Juliette Martin, Paulo C. T. Souza

Proteolysis targeting chimeras (PROTACS) are ligands that can mediate interaction between a protein target and a E3 ligase, forming a ternary complex bound to the ubiquitination machinery, leading to target degradation. This technology has become an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b1918daddb970ad2e01b89eb3ecc8a0
https://doi.org/10.1101/2023.02.16.528819

Implication of Terminal Residues at Protein-Protein and Protein-DNA Interfaces.

Autor: Olivier M F Martin, Loïc Etheve, Guillaume Launay, Juliette Martin

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162143 (2016)

Terminal residues of protein chains are charged and more flexible than other residues since they are constrained only on one side. Do they play a particular role in protein-protein and protein-DNA interfaces? To answer this question, we considered la

Externí odkaz: https://doaj.org/article/6b9b323d7b9f49669b75f793785e0841

The Det.Belt Server: A Tool to Visualize and Estimate Amphipathic Solvent Belts around Membrane Proteins

Autor: Pierre Falson, Sébastien Delolme, Juliette Martin, Mélanie Garnier, Vincent Chaptal, Yannick Gestin, Cécile Hilpert, Guillaume Launay, Veronica Zampieri

Publikováno v: Membranes
Membranes, MDPI, 2021, 11 (7), pp.459. ⟨10.3390/membranes11070459⟩
Volume 11
Issue 7
Membranes, Vol 11, Iss 459, p 459 (2021)

International audience; Detergents wrap around membrane proteins to form a belt covering the hydrophobic part of the protein serving for membrane insertion and interaction with lipids. The number of detergent monomers forming this belt is usually unk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a52c0017a8d54b7530b44a2ea20802
https://hal.archives-ouvertes.fr/hal-03454174/file/membranes-11-00459.pdf

Evaluation of CONSRANK-Like Scoring Functions for Rescoring Ensembles of Protein–Protein Docking Poses

Autor: Nobuyuki Uchikoga, Juliette Martin, Takanori Hayashi, Cécile Hilpert, Masahito Ohue, Yuri Matsuzaki, Julia Prieto Santero, Guillaume Launay

Publikováno v: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Frontiers Media, 2020, 7, ⟨10.3389/fmolb.2020.559005⟩
Frontiers in Molecular Biosciences, Vol 7 (2020)

Scoring is a challenging step in protein–protein docking, where typically thousands of solutions are generated. In this study, we ought to investigate the contribution of consensus-rescoring, as introduced by Oliva et al. (2013) with the CONSRANK m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e81b1590949311315246f56e5f7c9d
https://hal.archives-ouvertes.fr/hal-02988429