Administration of Bacteriophages via Nebulization during Mechanical Ventilation: In Vitro Study and Lung Deposition in Macaques

Autor: Sandrine Le Guellec, Jeoffrey Pardessus, Elsa Bodier-Montagutelli, Guillaume L’Hostis, Emilie Dalloneau, Damien Piel, Hakim Chouky Samaï, Antoine Guillon, Elvir Mujic, Emmanuelle Guillot-Combe, Stephan Ehrmann, Eric Morello, Jérôme Gabard, Nathalie Heuzé-Vourc’h, Cindy Fevre, Laurent Vecellio

Publikováno v: Viruses, Vol 15, Iss 3, p 602 (2023)

Bacteriophages have been identified as a potential treatment option to treat lung infection in the context of antibiotic resistance. We performed a preclinical study to predict the efficacy of delivery of bacteriophages against Pseudomonas aeruginosa

Externí odkaz: https://doaj.org/article/33e047181e534ee589203f384bc9a112

Inhaled phage therapy for the treatment of acute Pseudomonas aeruginosa lung infections

Autor: Emilie Dalloneau, Eric Morello, Laurent Vecellio, Cindy Fevre, Jérôme Gabard, Nathalie Heuzé-Vourc'h, Sandrine Le Guellec, Jeoffrey Pardessus, Elsa Bodier-Montagutelli, Renaud Respaud, Guillaume L'Hostis

Publikováno v: Respiratory infections.

Pseudomonas aeruginosa (Psa) lung infections are increasingly difficult to treat due to evolving antibiotic resistance; bacteriophages (phages) are part of the foreseen complementary/alternative therapies. In this study, we developed a phage cocktail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9c9c465fde47698fa18c3f030b1ab35
https://doi.org/10.1183/13993003.congress-2018.pa2649

Rapid urine preparation prior to identification of uropathogens by MALDI-TOF MS

Autor: S. Ghirardi, C. Ducruix, Victoria Girard, A. Richez, Bruno H. Muller, Hervé Rostaing, A. Lesenne, Guillaume L'Hostis, Laurent Veron, A. van Belkum, Sandrine Mailler, Frédéric Mallard, Veronique Lanet

Publikováno v: European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology. 34(9)

Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-ToF MS) has been introduced in clinical routine microbiology laboratories. For the rapid diagnosis of urinary tract infections, culture-independent methods prior MALD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2f600701e539552b6d2e272ce1fbd3
https://pubmed.ncbi.nlm.nih.gov/26054715

Bacterial Detection Using Unlabeled Phage Amplification and Mass Spectrometry through Structural and Nonstructural Phage Markers

Autor: Christine Rozand, Paulo Tavares, François Fenaille, Alain Theretz, Jean-Claude Tabet, Eric Ezan, Bruno H. Muller, Christophe Junot, S. Brasilès, Armelle Martelet, Guillaume L'Hostis, François Becher, Gaspard Gervasi

Publikováno v: Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2014, 13 (3), pp.1450--1465. ⟨10.1021/pr400991t⟩
Journal of Proteome Research, 2014, 13 (3), pp.1450--1465. ⟨10.1021/pr400991t⟩

According to the World Health Organization, food safety is an essential public health priority. In this context, we report a relevant proof of feasibility for the indirect specific detection of bacteria in food samples using unlabeled phage amplifica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f694bd166177d71ef3182be19a37e2
https://hal.archives-ouvertes.fr/hal-01664183