Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Guillaume Halet"'
Publikováno v:
Open Biology, Vol 13, Iss 3 (2023)
Polo-like kinase I (Plk1) is a highly conserved seronine/threonine kinase essential in meiosis and mitosis for spindle formation and cytokinesis. Here, through temporal application of Plk1 inhibitors, we identify a new role for Plk1 in the establishm
Externí odkaz:
https://doaj.org/article/e27f8bfaeaa746e782fb9c1d8306e088
Autor:
Benoit Dehapiot, Raphaël Clément, Anne Bourdais, Virginie Carrière, Sébastien Huet, Guillaume Halet
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001376 (2021)
Mammalian oocyte meiotic divisions are highly asymmetric and produce a large haploid gamete and 2 small polar bodies. This relies on the ability of the cell to break symmetry and position its spindle close to the cortex before anaphase occurs. In met
Externí odkaz:
https://doaj.org/article/f47342eb8aac4d47b454515302406523
Autor:
Diane Pelzer, Ludmilla de Plater, Peta Bradbury, Adrien Eichmuller, Anne Bourdais, Guillaume Halet, Jean-Léon Maître
Cell fragmentation occurs during physiological processes, such as apoptosis, migration, or germ cell development. Fragmentation is also commonly observed during preimplantation development of human embryos and is associated with poor implantation pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3653e8846ef6efad15975a7107ac3b31
https://doi.org/10.1101/2022.12.22.521568
https://doi.org/10.1101/2022.12.22.521568
Asymmetric meiotic divisions in oocytes rely on spindle positioning in close vicinity to the cortex. In mouse oocytes arrested at metaphase II, eccentric spindle positioning is associated with a chromatin-induced remodeling of the overlying cortex, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8507b06f976ade81d167694711ca5cd5
https://doi.org/10.1101/2022.09.25.509421
https://doi.org/10.1101/2022.09.25.509421
Publikováno v:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2021, 134 (24), pp.jcs259237. ⟨10.1242/jcs.259237⟩
Journal of Cell Science, 2022, 134 (24), pp.jcs259237. ⟨10.1242/jcs.259237⟩
Journal of Cell Science, Company of Biologists, 2022, 134 (24), pp.jcs259237. ⟨10.1242/jcs.259237⟩
Journal of Cell Science, Company of Biologists, 2021, 134 (24), pp.jcs259237. ⟨10.1242/jcs.259237⟩
Journal of Cell Science, 2022, 134 (24), pp.jcs259237. ⟨10.1242/jcs.259237⟩
Journal of Cell Science, Company of Biologists, 2022, 134 (24), pp.jcs259237. ⟨10.1242/jcs.259237⟩
How multiple actin networks coexist in a common cytoplasm while competing for a shared pool of monomers is still an ongoing question. This is exemplified by meiotic maturation in the mouse oocyte, which relies on the dynamic remodeling of distinct co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c5fea0871aaedc6344c1f1e60c6030
https://hal.science/hal-03485424
https://hal.science/hal-03485424
Autor:
Fabrice G. Petit, Soazik P. Jamin, Pierre-Yves Kernanec, Emmanuelle Becker, Guillaume Halet, Michael Primig
Publikováno v:
Developmental Biology
Developmental Biology, 2022, 483, pp.58-65. ⟨10.1016/j.ydbio.2021.12.010⟩
Developmental Biology, 2022, 483, pp.58-65. ⟨10.1016/j.ydbio.2021.12.010⟩
The conserved 3’-5’ exoribonuclease EXOSC10/Rrp6 is required for gametogenesis, brain development, erythropoiesis and blood cell enhancer function. The human ortholog is essential for mitosis in cultured cancer cells. Little is known, however, ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d320f9406e2a1d80d57c77566189feb
https://doi.org/10.1101/2021.10.06.463350
https://doi.org/10.1101/2021.10.06.463350
Autor:
Raphaël Clément, Anne Bourdais, Benoit Dehapiot, Virginie Carrière, Guillaume Halet, Sébastien Huet
Publikováno v:
PLoS Biology
PLoS Biology, Public Library of Science, 2021, 19 (9), pp.e3001376. ⟨10.1371/journal.pbio.3001376⟩
PLoS Biology, 2021, 19 (9), pp.e3001376. ⟨10.1371/journal.pbio.3001376⟩
PLoS Biology, Vol 19, Iss 9, p e3001376 (2021)
PLoS Biology, Public Library of Science, 2021, 19 (9), pp.e3001376. ⟨10.1371/journal.pbio.3001376⟩
PLoS Biology, 2021, 19 (9), pp.e3001376. ⟨10.1371/journal.pbio.3001376⟩
PLoS Biology, Vol 19, Iss 9, p e3001376 (2021)
Mammalian oocyte meiotic divisions are highly asymmetric and produce a large haploid gamete and 2 small polar bodies. This relies on the ability of the cell to break symmetry and position its spindle close to the cortex before anaphase occurs. In met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e1b487719df7bad74340af48777847
https://hal.archives-ouvertes.fr/hal-03368104
https://hal.archives-ouvertes.fr/hal-03368104
Autor:
Julie Guillermet-Guibert, Lee B Smith, Guillaume Halet, Maria A Whitehead, Wayne Pearce, Diane Rebourcet, Kelly León, Pascale Crépieux, Gemma Nock, Maria Strömstedt, Malin Enerback, Claude Chelala, Mariona Graupera, John Carroll, Sabina Cosulich, Philippa T K Saunders, Ilpo Huhtaniemi, Bart Vanhaesebroeck
Publikováno v:
PLoS Genetics, Vol 11, Iss 7, p e1005304 (2015)
The organismal roles of the ubiquitously expressed class I PI3K isoform p110β remain largely unknown. Using a new kinase-dead knockin mouse model that mimics constitutive pharmacological inactivation of p110β, we document that full inactivation of
Externí odkaz:
https://doaj.org/article/84615ca74de944419dd8124734c7eda0
Mammalian oocyte meiotic divisions are highly asymmetric and produce a large haploid gamete and two small polar bodies. This relies on the ability of the cell to break symmetry and position its spindle close to the cortex before the anaphase occurs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b976f914a0fd20e75dc2b2061e8e65
https://hal.science/hal-03035438/document
https://hal.science/hal-03035438/document