Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Guillaume Duménil"'
Autor:
David Fernandez-Martinez, Youxin Kong, Sylvie Goussard, Agustin Zavala, Pauline Gastineau, Martial Rey, Gabriel Ayme, Julia Chamot-Rooke, Pierre Lafaye, Matthijn Vos, Ariel Mechaly, Guillaume Duménil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Type IV pili (T4P) are prevalent, polymeric surface structures in pathogenic bacteria, making them ideal targets for effective vaccines. However, bacteria have evolved efficient strategies to evade type IV pili-directed antibody responses. N
Externí odkaz:
https://doaj.org/article/b31d21f500b94edeab7636033fb2229e
Autor:
David Fernandez-Martinez, Youxin Kong, Sylvie Goussard, Agustin Zavala, Pauline Gastineau, Martial Rey, Gabriel Ayme, Julia Chamot-Rooke, Pierre Lafaye, Matthijn Vos, Ariel Mechaly, Guillaume Duménil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/34f003db6b68436cb5bef04957df0cbb
Autor:
Valeria Manriquez, Pierre Nivoit, Tomas Urbina, Hebert Echenique-Rivera, Keira Melican, Marie-Paule Fernandez-Gerlinger, Patricia Flamant, Taliah Schmitt, Patrick Bruneval, Dorian Obino, Guillaume Duménil
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The human pathogen Neisseria meningitidis colonizes blood vessels and causes vascular damage, despite a neutrophil-rich inflammatory infiltrate. Here, Manriquez et al. use a humanized mouse model to show that pathogen colonization of capillaries and
Externí odkaz:
https://doaj.org/article/3831caa54fa047ecaa07a6a930b57045
Autor:
Rémy Robinot, Mathieu Hubert, Guilherme Dias de Melo, Françoise Lazarini, Timothée Bruel, Nikaïa Smith, Sylvain Levallois, Florence Larrous, Julien Fernandes, Stacy Gellenoncourt, Stéphane Rigaud, Olivier Gorgette, Catherine Thouvenot, Céline Trébeau, Adeline Mallet, Guillaume Duménil, Samy Gobaa, Raphaël Etournay, Pierre-Marie Lledo, Marc Lecuit, Hervé Bourhy, Darragh Duffy, Vincent Michel, Olivier Schwartz, Lisa A. Chakrabarti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
SARS-CoV-2 infection damages the airways. Here the authors show that SARS-CoV-2 infection induces the rapid loss of airway motile cilia, resulting in altered cilia clearance function. Cilia loss is preceded by reduced expression of the ciliogenesis r
Externí odkaz:
https://doaj.org/article/8bf151f6060345a3ae7b514eb9de5a9b
Autor:
Arthur Charles-Orszag, Feng-Ching Tsai, Daria Bonazzi, Valeria Manriquez, Martin Sachse, Adeline Mallet, Audrey Salles, Keira Melican, Ralitza Staneva, Aurélie Bertin, Corinne Millien, Sylvie Goussard, Pierre Lafaye, Spencer Shorte, Matthieu Piel, Jacomine Krijnse-Locker, Françoise Brochard-Wyart, Patricia Bassereau, Guillaume Duménil
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Meningococci remodel the plasma membrane of host cells during infection. Here, Charles-Orszag et al. show that plasma membrane remodeling occurs independently of F-actin, along meningococcal type IV pili fibers, by a physical mechanism that they term
Externí odkaz:
https://doaj.org/article/a3ee3d2a3841419284f54580f2ed54ad
Autor:
Joseph Gault, Mathias Ferber, Silke Machata, Anne-Flore Imhaus, Christian Malosse, Arthur Charles-Orszag, Corinne Millien, Guillaume Bouvier, Benjamin Bardiaux, Gérard Péhau-Arnaudet, Kelly Klinge, Isabelle Podglajen, Marie Cécile Ploy, H Steven Seifert, Michael Nilges, Julia Chamot-Rooke, Guillaume Duménil
Publikováno v:
PLoS Pathogens, Vol 11, Iss 9, p e1005162 (2015)
The ability of pathogens to cause disease depends on their aptitude to escape the immune system. Type IV pili are extracellular filamentous virulence factors composed of pilin monomers and frequently expressed by bacterial pathogens. As such they are
Externí odkaz:
https://doaj.org/article/c812641b2ddc477ebd7bf615b83e9433
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003139 (2013)
Septic shock caused by Neisseria meningitidis is typically rapidly evolving and often fatal despite antibiotic therapy. Further understanding of the mechanisms underlying the disease is necessary to reduce fatality rates. Postmortem samples from the
Externí odkaz:
https://doaj.org/article/6d0302ba2dc94fa3ac2b876651147aaf
Autor:
Yoan Konto-Ghiorghi, Emilie Mairey, Adeline Mallet, Guillaume Duménil, Elise Caliot, Patrick Trieu-Cuot, Shaynoor Dramsi
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000422 (2009)
Streptococcus agalactiae is a common human commensal and a major life-threatening pathogen in neonates. Adherence to host epithelial cells is the first critical step of the infectious process. Pili have been observed on the surface of several gram-po
Externí odkaz:
https://doaj.org/article/b60477d291964540857050f0d20ff622
Autor:
Guillain Mikaty, Magali Soyer, Emilie Mairey, Nelly Henry, Dave Dyer, Katrina T Forest, Philippe Morand, Stéphanie Guadagnini, Marie Christine Prévost, Xavier Nassif, Guillaume Duménil
Publikováno v:
PLoS Pathogens, Vol 5, Iss 2, p e1000314 (2009)
Bacterial infections targeting the bloodstream lead to a wide array of devastating diseases such as septic shock and meningitis. To study this crucial type of infection, its specific environment needs to be taken into account, in particular the mecha
Externí odkaz:
https://doaj.org/article/3c4c1d35acc84a49a6799d90a3b75283
Autor:
Guillaume Duménil
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3e6d6c148c0534959ac393674bc754
https://doi.org/10.1016/b978-0-12-821618-7.00275-3
https://doi.org/10.1016/b978-0-12-821618-7.00275-3