Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Guillaume Droogmans"'
Autor:
M. Satpathy, Beatrice Y.J.T. Yue, L H Goon, Sangly P. Srinivas, Guillaume Droogmans, L Goon, Bernd Nilius, Chantal Maertens
Publikováno v:
Experimental Eye Research. 78:15-26
Purpose . Hyposmolar perfusion of intact trabecular meshwork (TM) induces a decrease in its hydraulic conductivity (Lp). However, exposure to agents that elevate intracellular cAMP in TM cells increases Lp. Since volume of TM cells could directly inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6656753aee6082defaafb8572918670d
https://doi.org/10.1016/j.exer.2003.10.001
https://doi.org/10.1016/j.exer.2003.10.001
Autor:
Guillaume Droogmans, Bernd Nilius
Publikováno v:
Acta Physiologica Scandinavica. 177:119-147
Aim: This review describes molecular and functional properties of the following Cl - channels: the ClC family of voltage-dependent Cl - channels, the cAMP-activated transmembrane conductance regulator (CFTR), Ca 2+ activated Cl - channels (CaCC) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dcb8aaeb91574261e329c22c802aaf5
https://doi.org/10.1046/j.1365-201x.2003.01060.x
https://doi.org/10.1046/j.1365-201x.2003.01060.x
Autor:
Iris Carton, Dominique Trouet, Diane Hermans, Guillaume Droogmans, Jan Eggermont, Bernd Nilius
Publikováno v:
American Journal of Physiology-Cell Physiology. 281:C248-C256
We used the whole cell patch-clamp technique in calf pulmonary endothelial (CPAE) cells to investigate the effect of wild-type and mutant c-Src tyrosine kinase on ICl,swell, the swelling-induced Cl−current through volume-regulated anion channels (V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d5792e5d69c7d815352d0da8f3b10f
https://doi.org/10.1152/ajpcell.2001.281.1.c248
https://doi.org/10.1152/ajpcell.2001.281.1.c248
Publikováno v:
Biochemical and Biophysical Research Communications. 284:461-465
Caveolae are flask-shaped invaginations of the plasma membrane formed by the association of caveolin proteins with lipid rafts. In endothelial cells, caveolae function as signal transduction centers controlling NO synthesis and mechanotransduction. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e60d067b5e009ee255b68ecc51e9cf
https://doi.org/10.1006/bbrc.2001.4995
https://doi.org/10.1006/bbrc.2001.4995
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 442:273-279
Using the whole-cell patch-clamp technique, we have studied the electrophysiological and pharmacological properties of the Ca(2+)-activated Cl- current present in Ehrlich cells. The currents activated slowly upon depolarization, deactivated upon hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c1aed3492fa5c3c09e5f31e98e3517
https://doi.org/10.1007/s004240100526
https://doi.org/10.1007/s004240100526
Autor:
Jean-Jacques Cassiman, Bernd Nilius, Anne Vankeerberghen, Guillaume Droogmans, Lin Wei, Harry Cuppens
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 442:280-285
Expression of the cystic fibrosis transmembrane conductance regulator (CFTR) inhibits Ca(2+)-activated Cl- channels (CaCC) by an unknown mechanism. This inhibition does not require CFTR activation (activity-independent inhibition), but is potentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aacd90a2d4ef76068170bb9c810349c8
https://doi.org/10.1007/s004240100531
https://doi.org/10.1007/s004240100531
Publikováno v:
British Journal of Pharmacology. 132:135-142
1. We have used the whole-cell patch clamp technique to study the effect of the partial anti-oestrogens clomiphene and nafoxidine, the pure anti-oestrogens ICI 182,780 and RU 58,668 and the oestrogen ss-estradiol, on the volume-regulated anion channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c58ea5a77f1cf1ad33a17748091d5dc0
https://doi.org/10.1038/sj.bjp.0703786
https://doi.org/10.1038/sj.bjp.0703786
Autor:
Jean Prenen, Guillaume Droogmans, Rudi Vennekens, René J. M. Bindels, Joost G. J. Hoenderop, Bernd Nilius
Publikováno v:
Cell Calcium, 29, 417-428
Cell Calcium, 29, 417--28
Cell Calcium, 29, 6, pp. 417-428
Cell Calcium, 29, 6, pp. 417--28
Cell Calcium, 29, 417--28
Cell Calcium, 29, 6, pp. 417-428
Cell Calcium, 29, 6, pp. 417--28
Item does not contain fulltext We have studied the modulation by intracellular Ca2+ of the epithelial Ca2+ channel, ECaC, heterologously expressed in HEK 293 cells. Whole-cell and inside-out patch clamp current recordings were combined with FuraII-Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37780fecbf485ee0d777c1d999517b03
https://hdl.handle.net/2066/29937
https://hdl.handle.net/2066/29937
Publikováno v:
British Journal of Pharmacology. 129:791-801
It was the aim of this study to look for a high-affinity and selective polypeptide toxin, which could serve as a probe for the volume-regulated anion channel (VRAC) or the calcium-activated chloride channel (CaCC). We have partially purified chloroto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069a90fec37e6afa53bc65264fa75e3f
https://doi.org/10.1038/sj.bjp.0703102
https://doi.org/10.1038/sj.bjp.0703102
Autor:
Bernd Nilius, Jean-Jacques Cassiman, Guillaume Droogmans, Harry Cuppens, Jan Eggermont, Lin Wei, Anne Vankeerberghen
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 438:635-641
We investigated interactions between cystic fibrosis conductance regulator (CFTR) and endogenous Ca2+-activated Cl- channels (CaCC) in bovine pulmonary artery endothelium (CPAE). CPAE cells, which do not express CFTR, were transiently transfected wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f067838bed868bf720a6958cfaafb58c
https://doi.org/10.1007/s004240051087
https://doi.org/10.1007/s004240051087