Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Guillaume Dighiero"'
Autor:
Luis Borche, Guillaume Dighiero
Publikováno v:
Leukemialymphoma. 5
Autoreactive B cells constitute a substantial part of B cell repertoire. They frequently secrete polyspecific natural autoantibodies, which are the expression of germinal genes. During recent years considerable evidence has accumulated indicating tha
Autor:
Guillaume Dighiero
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 193:1361-1368
RESUME Cree par Louis Pasteur, le reseau International des Instituts Pasteur compte aujourd’hui trente instituts repartis parmi les cinq continents. L’Institut Pasteur de Montevideo, est le plus recent. Inaugure en decembre 2006 par le President
Publikováno v:
EMC - Hématologie. 1:1-12
Autor:
Otto Pritsch, Alfonso Cayota, Jean-Pierre Bouvet, Pablo Oppezzo, Carlos Robello, Gérard Dumas, Juan C. Pizarro, Guillaume Dighiero
Publikováno v:
European Journal of Immunology. 34:1423-1432
Although antibodies have been assumed to bind a specific antigen, evidence exists showing that a single antibody can bind to multiple unrelated antigens. We previously studied a human monoclonal antibody expressing a mutated form of the V(H)3-73 gene
Autor:
Guillaume Dighiero
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 186:1251-1268
RESUME La LLC est une hemopathie lymphoide chronique definie par l’accumulation de petits lymphocytes B avec une morphologie et un phenotype caracteristiques, une activite autoreactive et une resistance accrue a l’apoptose. Environ un tiers des m
Publikováno v:
British Journal of Haematology. 118:976-985
B-cell chronic lymphocytic leukaemia (B-CLL) characteristically displays low amounts of B-cell receptor (BCR), which mainly consists of the heterodimer CD79a/CD79b bound non-covalently with the surface immunoglobulin (SIg). This heterodimer is requir
Autor:
Guillaume Dighiero, Christine Pourcel, Patrick Ave, Gérard Dumas, Michel Huerre, Isabelle Chambaud, Alain Blanchard, Séverine Havouis
Publikováno v:
European Journal of Immunology. 32:1147-1156
‐cells, which expressed the transgenic immunoglobulin. Immunization of the transgenic mice with keyhole limpet hemocyanin and Freund’s adjuvant, to nonspecifically stimulate the expression of the passenger transgenes, only moderately increased th
Autor:
Elaine K. Thomas, Colette Jouanne, Daniel Scott-Algara, Guillaume Dighiero, Karim Maloum, Françoise Vuillier
Publikováno v:
British Journal of Haematology. 115:831-844
Chronic lymphocytic leukaemia (CLL) remains an incurable disease. Although modern available treatments are able to induce disease regression, relapse almost inexorably occurs. Therefore, novel therapeutic strategies aimed at reducing the disease rela
Autor:
Guillaume Dighiero, Bernard Desablens, M. J. Rapp, Bruno Cazin, Brigitte Dreyfus, Najda Boudjerra, Marine Divine, Claude Chastang, Karim Maloum, Pierre Feugier, Sylvie Chevret, Philippe Travade, Claudie Autrand, Jérôme Jaubert, Michel Leporrier, Jacques-Louis Binet
Publikováno v:
Blood. 98:2319-2325
To comparatively assess first-line treatment with fludarabine and 2 anthracycline-containing regimens, namely CAP (cyclophosphamide, doxorubicin plus prednisone) and ChOP (cyclophosphamide, vincristine, prednisone plus doxorubicin), in advanced stage
Publikováno v:
Revue Française des Laboratoires. 2000:57-60
Resume Les reponses auto-immunes sont sous le controle de circuits de regulation tres complexes. Les maladies auto-immunes presentent frequemment un profil anormal de secretion des cytokines. Des travaux recents ont souligne que des facteurs regulant