Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Guillaume Beauclair"'
Autor:
Anvita Bhargava, Ugo Szachnowski, Maxime Chazal, Dominika Foretek, Vincent Caval, Sophie-Marie Aicher, Juliana Pipoli da Fonseca, Patricia Jeannin, Guillaume Beauclair, Marc Monot, Antonin Morillon, Nolwenn Jouvenet
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108449- (2023)
Summary: Investigations of cellular responses to viral infection are commonly performed on mixed populations of infected and uninfected cells or using single-cell RNA sequencing, leading to inaccurate and low-resolution gene expression interpretation
Externí odkaz:
https://doaj.org/article/189c398d95884a2288a35ecacb3cc0e2
Autor:
Nicolas Vabret, Valérie Najburg, Alexander Solovyov, Ramya Gopal, Christopher McClain, Petr Šulc, Sreekumar Balan, Yannis Rahou, Guillaume Beauclair, Maxime Chazal, Hugo Varet, Rachel Legendre, Odile Sismeiro, Raul Y. Sanchez David, Lise Chauveau, Nolwenn Jouvenet, Martin Markowitz, Sylvie van der Werf, Olivier Schwartz, Frédéric Tangy, Nina Bhardwaj, Benjamin D. Greenbaum, Anastassia V. Komarova
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104599- (2022)
Summary: Pattern recognition receptors (PRRs) protect against microbial invasion by detecting specific molecular patterns found in pathogens and initiating an immune response. Although microbial-derived PRR ligands have been extensively characterized
Externí odkaz:
https://doaj.org/article/3f866d774d69450aaefc5a05b8e28df1
Autor:
Florian Bakoa, Christophe Préhaud, Guillaume Beauclair, Maxime Chazal, Nathalie Mantel, Monique Lafon, Nolwenn Jouvenet
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Mass vaccination with the live attenuated vaccine YF-17D is the current way to prevent infection with Yellow fever virus (YFV). However, 0.000012–0.00002% of vaccinated patients develop post-vaccination neurological syndrome (YEL-AND). Und
Externí odkaz:
https://doaj.org/article/3250ab5afc1042ee8bd3d7363697f181
Autor:
Damien Glon, Géraldine Vilmen, Daniel Perdiz, Eva Hernandez, Guillaume Beauclair, Frédérique Quignon, Clarisse Berlioz-Torrent, Vincent Maréchal, Christian Poüs, Marion Lussignol, Audrey Esclatine
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010371 (2022)
Innate immunity constitutes the first line of defense against viruses, in which mitochondria play an important role in the induction of the interferon (IFN) response. BHRF1, a multifunctional viral protein expressed during Epstein-Barr virus reactiva
Externí odkaz:
https://doaj.org/article/5d8641857bb34b9cbec3012f784e8e7e
Autor:
Noémie Berry, Rodolphe Suspène, Vincent Caval, Pierre Khalfi, Guillaume Beauclair, Stéphane Rigaud, Hervé Blanc, Marco Vignuzzi, Simon Wain-Hobson, Jean-Pierre Vartanian
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Viruses have evolved a plethora of mechanisms to impair host innate immune responses. Herpes simplex virus type 1 (HSV-1), a double-stranded linear DNA virus, impairs the mitochondrial network and dynamics predominantly through the UL12.5 ge
Externí odkaz:
https://doaj.org/article/32d083226e664230aca054c0479db6e7
Autor:
Maxime Chazal, Guillaume Beauclair, Ségolène Gracias, Valérie Najburg, Etienne Simon-Lorière, Frédéric Tangy, Anastassia V. Komarova, Nolwenn Jouvenet
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 320-328 (2018)
Summary: The flavivirus genus comprises major human pathogens, such as Dengue (DENV) and Zika (ZIKV) viruses. RIG-I and MDA5 are key cytoplasmic pathogen recognition receptors that are implicated in detecting viral RNAs. Here, we show that RNAs that
Externí odkaz:
https://doaj.org/article/963cc1426b324aa49de56b7779c61c56
Autor:
Lucie Danet, Guillaume Beauclair, Michèle Berthet, Gonzalo Moratorio, Ségolène Gracias, Frédéric Tangy, Valérie Choumet, Nolwenn Jouvenet
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007299 (2019)
BackgroundTo be transmitted to vertebrate hosts via the saliva of their vectors, arthropod-borne viruses have to cross several barriers in the mosquito body, including the midgut infection and escape barriers. Yellow fever virus (YFV) belongs to the
Externí odkaz:
https://doaj.org/article/d6bdf7766b5d41dbb5b1f7bcdf3ba1b2
Publikováno v:
Viruses, Vol 11, Iss 1, p 68 (2019)
Flaviviruses, such as dengue (DENV), West Nile (WNV), yellow fever (YFV) and Zika (ZIKV) viruses, are mosquito-borne pathogens that present a major risk to global public health. To identify host factors that promote flavivirus replication, we perform
Externí odkaz:
https://doaj.org/article/dce8601e38274394a2e3d75c912986b8
Autor:
Pierre Khalfi, Rodolphe Suspène, Vincent Caval, Valérie Thiers, Guillaume Beauclair, Agnès Marchio, Claudine Bekondi, Marie Amougou Atsama, Serge Magloire Camengo-Police, Dominique Noah Noah, Richard Njouom, Hervé Blanc, Thomas Vallet, Marco Vignuzzi, Pascal Pineau, Jean Pierre Vartanian
Publikováno v:
Journal of Infectious Diseases
Journal of Infectious Diseases, 2022, pp.jiac003. ⟨10.1093/infdis/jiac003⟩
Journal of Infectious Diseases, 2022, pp.jiac003. ⟨10.1093/infdis/jiac003⟩
Single-nucleotide polymorphism in APOBEC3C (resulting in a serine to isoleucine in position 188) is present in approximately 10% of African populations and greatly enhances restriction against human immunodeficiency virus-1 and simian immunodeficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35fc36e404b65c1a02590f38d4810bfa
https://doi.org/10.1093/infdis/jiac003
https://doi.org/10.1093/infdis/jiac003
Publikováno v:
Virologie (Montrouge, France). 14(5)
Post-translational modifications, such as SUMOylation, are exam- ples of cellular machineries hijacked by viruses to efficiently replicate. SUMOylation, which consists in the conjugation of small ubiquitin-like modi- fier (SUMO) peptides to a substra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26da4b3c469bef63dd7866b3c1c4e983
https://pubmed.ncbi.nlm.nih.gov/36151696
https://pubmed.ncbi.nlm.nih.gov/36151696