Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Guillaume Barre"'
Autor:
Laurence Millet, Angelina Besse, Stéphanie Tissandié, Gernot Zech, Marie-Francoise Bordes, Alain Badorc, Lassalle Gilbert, Valerie Fossey, Jean-Pascal Herault, Frédérique Dol, Christophe Boldron, Benjamin Gau, Christophe Briot, Nathalie Delesque, Anne-Marie Pflieger, Françoise Bono, Xavier Yvon, Marc Nazaré, Guillaume Barre, Tristan Rousseaux, Jean-Marc Herbert, Sandrine Bonnet-Lignon, Jerome Meneyrol, Pierre Savi
Publikováno v:
Journal of medicinal chemistry. 57(17)
In the search of a potential backup for clopidogrel, we have initiated a HTS campaign designed to identify novel reversible P2Y12 antagonists. Starting from a hit with low micromolar binding activity, we report here the main steps of the optimization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291b64860ee2ed44163c467111c8fa67
https://pubmed.ncbi.nlm.nih.gov/25075638
https://pubmed.ncbi.nlm.nih.gov/25075638
Autor:
Christophe Briot, Paul J. Schaeffer, Jean-Michel Altenburger, Herman Schreuder, Tristan Rousseaux, Guillaume Barre, Lassalle Gilbert, Frédérique Dol, Laurence Millet, Jean-Marc Herbert, Jerome Meneyrol, Freddy Sadoun, Peter Florian, Frédéric Petit, Jean-Pascal Herault, Zsolt Böcskei, Volkmar Wehner, Markus Follmann, Françoise Bono, Nathalie Alet, Sylvie Klieber
Publikováno v:
Journal of medicinal chemistry. 56(23)
Compound 15 (SAR107375), a novel potent dual thrombin and factor Xa inhibitor resulted from a rational optimization process. Starting from compound 14, with low factor Xa and modest anti-thrombin inhibitory activities (IC50's of 3.5 and 0.39 μM, res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064f073674852fbbf59b1b916074c508
https://pubmed.ncbi.nlm.nih.gov/24175584
https://pubmed.ncbi.nlm.nih.gov/24175584
Autor:
Edouard Stavaux, François Goupil, Guillaume Barreau, Anne Lise Septans, Bertrand Dautzenberg, Armelle Foulet-Rogé, Norbert Padilla, Thierry Urban, Fabrice Denis
Publikováno v:
JMIR Public Health and Surveillance, Vol 8, Iss 2, p e19877 (2022)
BackgroundPatient self-assessment via a mobile app detects actionable symptoms and has been shown to detect lung cancer relapses early, thereby lengthening survival. ObjectiveThe purpose of this study was to assess the incidence of chief symptoms as
Externí odkaz:
https://doaj.org/article/7ccad415e9114c8abb6c61d89806cf91
Autor:
Katherine Légaré, Reza Safaei, Guillaume Barrette, Loïc Arias, Philippe Lassonde, Heide Ibrahim, Boris Vodungbo, Emmanuelle Jal, Jan Lüning, Nicolas Jaouen, Zhensheng Tao, Andrius Baltuška, François Légaré, Guangyu Fan
Publikováno v:
Advanced Photonics Research, Vol 2, Iss 11, Pp n/a-n/a (2021)
The use of ultrashort laser pulses with long wavelengths as drivers is a relevant strategy for scaling high harmonic generation (HHG) to higher photon energies. Here, stimulated Raman scattering enhanced by the formation of multidimensional solitary
Externí odkaz:
https://doaj.org/article/54668e3c02614cba88cf68b0fefa2028
Autor:
Nicolas Lefeuvre, Laurent Truche, Frédéric‐Victor Donzé, Maxime Ducoux, Guillaume Barré, Rose‐Adeline Fakoury, Sylvain Calassou, Eric C. Gaucher
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 22, Iss 8, Pp n/a-n/a (2021)
Abstract Native hydrogen (H2) may represent a new carbon free‐energy resource, but to date there is no specific exploration guide to target H2‐fertile geological settings. Here, we present the first soil gas survey specifically designed to explor
Externí odkaz:
https://doaj.org/article/a8d846dd1297474a9e89503085f713b8