Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Guillaume BE Stewart-Jones"'
Autor:
Andrew J Borst, Connor E Weidle, Matthew D Gray, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume BE Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler
Publikováno v:
eLife, Vol 7 (2018)
VRC01 broadly neutralizing antibodies (bnAbs) target the CD4-binding site (CD4BS) of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein (Env). Unlike mature antibodies, corresponding VRC01 germline precursors poorly bind to Env. Immunog
Externí odkaz:
https://doaj.org/article/a11468bd4dce41cdae2356acea7e4869
Autor:
Helen M. Parrington, Nurgun Kose, Erica Armstrong, Laura Handal, Summer Diaz, Joseph Reidy, Jinhui Dong, Guillaume B.E. Stewart-Jones, Punya Shrivastava-Ranjan, Shilpi Jain, César G. Albariño, Robert H. Carnahan, James E. Crowe Jr.
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Sosuga virus (SOSV) is a recently discovered paramyxovirus with a single known human case of disease. There has been little laboratory research on SOSV pathogenesis or immunity, and no approved therapeutics or vaccines are available. Here, we report
Externí odkaz:
https://doaj.org/article/9a5bed5c525b465cbcb313853b6d22ab
Autor:
M. Gordon Joyce, Ivelin S. Georgiev, Yongping Yang, Aliaksandr Druz, Hui Geng, Gwo-Yu Chuang, Young Do Kwon, Marie Pancera, Reda Rawi, Mallika Sastry, Guillaume B.E. Stewart-Jones, Angela Zheng, Tongqing Zhou, Misook Choe, Joseph G. Van Galen, Rita E. Chen, Christopher R. Lees, Sandeep Narpala, Michael Chambers, Yaroslav Tsybovsky, Ulrich Baxa, Adrian B. McDermott, John R. Mascola, Peter D. Kwong
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2992-3002 (2017)
Summary: The elicitation of autologous neutralizing responses by immunization with HIV-1 envelope (Env) trimers conformationally stabilized in a prefusion closed state has generated considerable interest in the HIV-1 vaccine field. However, soluble p
Externí odkaz:
https://doaj.org/article/35ee43d1684f4a76bd9b745216501691
Autor:
Tongqing Zhou, Nicole A. Doria-Rose, Cheng Cheng, Guillaume B.E. Stewart-Jones, Gwo-Yu Chuang, Michael Chambers, Aliaksandr Druz, Hui Geng, Krisha McKee, Young Do Kwon, Sijy O’Dell, Mallika Sastry, Stephen D. Schmidt, Kai Xu, Lei Chen, Rita E. Chen, Mark K. Louder, Marie Pancera, Timothy G. Wanninger, Baoshan Zhang, Anqi Zheng, S. Katie Farney, Kathryn E. Foulds, Ivelin S. Georgiev, M. Gordon Joyce, Thomas Lemmin, Sandeep Narpala, Reda Rawi, Cinque Soto, John-Paul Todd, Chen-Hsiang Shen, Yaroslav Tsybovsky, Yongping Yang, Peng Zhao, Barton F. Haynes, Leonidas Stamatatos, Michael Tiemeyer, Lance Wells, Diana G. Scorpio, Lawrence Shapiro, Adrian B. McDermott, John R. Mascola, Peter D. Kwong
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 719-732 (2017)
While the HIV-1-glycan shield is known to shelter Env from the humoral immune response, its quantitative impact on antibody elicitation has been unclear. Here, we use targeted deglycosylation to measure the impact of the glycan shield on elicitation
Externí odkaz:
https://doaj.org/article/aabe08812b3841a8a0593b8fc0b38355
Autor:
Guillaume B.E. Stewart-Jones, Sayda M. Elbashir, Kai Wu, Diana Lee, Isabella Renzi, Baoling Ying, Matthew Koch, Caralyn E. Sein, Angela Choi, Bradley Whitener, Dario Garcia-Dominguez, Carole Henry, Angela Woods, LingZhi Ma, Daniela Montes Berrueta, Laura E. Avena, Julian Quinones, Samantha Falcone, Chiaowen J. Hsiao, Suzanne M. Scheaffer, Larissa B. Thackray, Phil White, Michael S. Diamond, Darin K. Edwards, Andrea Carfi
Publikováno v:
bioRxiv
With the success of mRNA vaccines against coronavirus disease 2019 (COVID-19), strategies can now focus on improving vaccine potency, breadth, and stability. We present the design and preclinical evaluation of domain-based mRNA vaccines encoding the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe8958c3e87fbf6d9c9bca9931512ac
https://europepmc.org/articles/PMC9558437/
https://europepmc.org/articles/PMC9558437/
Autor:
Nicola J, Borthwick, Maximillian, Rosario, Torben, Schiffner, Emma, Bowles, Tina, Ahmed, Peter, Liljeström, Guillaume E, Stewart-Jones, Jan W, Drijfhout, Cornelis J M, Melief, Tomáš, Hanke
Publikováno v:
Immunity, Inflammation and Disease
Vaccines delivering T cell immunogen HIVconsv vectored by plasmid DNA, non-replicating simian adenovirus and non-replicating modified vaccinia virus Ankara (MVA) are under clinical evaluation in phase I/IIa trials in UK, Europe, and Africa. While the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebb800aafee701c14f7059c57d41afcd
https://pubmed.ncbi.nlm.nih.gov/26029368
https://pubmed.ncbi.nlm.nih.gov/26029368
Autor:
Jim Boonyaratanakornkit, Suruchi Singh, Connor Weidle, Justas Rodarte, Ramasamy Bakthavatsalam, Jonathan Perkins, Guillaume B.E. Stewart-Jones, Peter D. Kwong, Andrew T. McGuire, Marie Pancera, Justin J. Taylor
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Human parainfluenza virus type III (HPIV3) is a common respiratory pathogen that afflicts children and can be fatal in vulnerable populations, including the immunocompromised. There are currently no effective vaccines or therapeutics available, resul
Externí odkaz:
https://doaj.org/article/f6bc168af44a4d7f913a61444d30c4e3