Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Guillaume A. Petit"'
CryptoGPT: a 7B model competing with GPT-4 in a specific task -- The Impact of Automatic Annotation and Strategic Fine-Tuning via QLoRAIn this article, we present a method aimed at refining a dedicated LLM of reasonable quality with limited resources
Externí odkaz:
http://arxiv.org/abs/2406.14039
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241306 (2020)
Identification of bacterial virulence factors is critical for understanding disease pathogenesis, drug discovery and vaccine development. In this study we used two approaches to predict virulence factors of Burkholderia pseudomallei, the Gram-negativ
Externí odkaz:
https://doaj.org/article/d050665dfa0a423080298c76ae1006cd
Autor:
Signe Christensen, Maria A Halili, Natalie Strange, Guillaume A Petit, Wilhelmina M Huston, Jennifer L Martin, Róisín M McMahon
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222595 (2019)
Chlamydia trachomatis is an obligate intracellular bacterium with a distinctive biphasic developmental cycle that alternates between two distinct cell types; the extracellular infectious elementary body (EB) and the intracellular replicating reticula
Externí odkaz:
https://doaj.org/article/434b135bcd6e432aacf0c1d7d3ecdb8c
Autor:
Sara Ullsten, Guillaume A. Petit, Johan Isaksson, Ida K. Ø. Hansen, Yannik K.-H. Schneider, Marte Jenssen, Chun Li, Kine Ø. Hansen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15852
Isolation of bioactive products from the marine environment is considered a very promising approach to identify new compounds that can be used for further drug development. In this work we have isolated three new compounds from the purpuroine family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33cfa205d364f79ae22cb631b786b27
https://hdl.handle.net/10037/28231
https://hdl.handle.net/10037/28231
Autor:
Sara, Ullsten, Guillaume A, Petit, Johan, Isaksson, Ida K Ø, Hansen, Yannik K-H, Schneider, Marte, Jenssen, Chun, Li, Kine Ø, Hansen
Publikováno v:
International journal of molecular sciences. 23(24)
Isolation of bioactive products from the marine environment is considered a very promising approach to identify new compounds that can be used for further drug development. In this work we have isolated three new compounds from the purpuroine family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a62602ef42d0093a59e0cadfdf0faa4b
https://pubmed.ncbi.nlm.nih.gov/36555494
https://pubmed.ncbi.nlm.nih.gov/36555494
Autor:
Russell J. Jarrott, Emily J. Furlong, Guillaume A. Petit, David Drew, Jennifer L. Martin, Maria A. Halili
Publikováno v:
Protein expression and purification. 193
Suppressor of copper sensitivity (Scs) proteins play a role in the bacterial response to copper stress in many Gram-negative bacteria, including in the human pathogen Proteus mirabilis. Recently, the ScsC protein from P. mirabilis (PmScsC) was charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633ac3f62492383917734f208d4ec9d4
https://pubmed.ncbi.nlm.nih.gov/35026386
https://pubmed.ncbi.nlm.nih.gov/35026386
Autor:
Roisin McMahon, David Hilko, Guillaume Axel Petit, Biswaranjan Mohanty, Karyn Wilde, Stefan Nebl, Martin Scanlon, Jennifer L. Martin, Maria Halili
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
The binding properties of two drug-like fragments to a conformationally dynamic site in disulfide bond-forming protein A from B. pseudomallei are described.
Disulfide-bond-forming proteins (Dsbs) play a crucial role in the pathogenicity of many
Disulfide-bond-forming proteins (Dsbs) play a crucial role in the pathogenicity of many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ebee7ded4dabde2f3b2aee1f7121cd
https://pubmed.ncbi.nlm.nih.gov/34981764
https://pubmed.ncbi.nlm.nih.gov/34981764
Autor:
Róisín M. McMahon, Hilko Dh, Nebl S, Maria A. Halili, Guillaume A. Petit, Wylde Kl, Biswaranjan Mohanty, Jennifer L. Martin, Martin J. Scanlon
DiSulfide Bond forming proteins (DSB) play a crucial role in the pathogenicity of many Gram-negative bacteria. Disulfide bond protein A (DsbA) catalyzes the formation of disulfide bonds necessary for the activity and stability of multiple substrate p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c11186e69e6c063b8c010d65d34e0dc0
https://doi.org/10.1101/2021.03.25.436878
https://doi.org/10.1101/2021.03.25.436878
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241306 (2020)
PLoS ONE
PLoS ONE
Identification of bacterial virulence factors is critical for understanding disease pathogenesis, drug discovery and vaccine development. In this study we used two approaches to predict virulence factors ofBurkholderia pseudomallei, the Gram-negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcd4821df6d9d6ba7f7c83b968fd345
https://doaj.org/article/d050665dfa0a423080298c76ae1006cd
https://doaj.org/article/d050665dfa0a423080298c76ae1006cd
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C1115-C1115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2dc7a6551d35d1639b8002e2d3543a4
https://doi.org/10.1107/s0108767321085901
https://doi.org/10.1107/s0108767321085901