Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Guillaume, Serin"'
Autor:
Federica Pappalardo, Francisco Romero Lairado, Cyprien Louis de Canonville, Céline Martin, Gregory Giacometti, Guillaume Serin, Eric Salomon, Thierry Angot, Laurent Gallais, Régis Bisson, Marco Minissale
Publikováno v:
Optics, Vol 3, Iss 3, Pp 216-224 (2022)
Tungsten (W) is the material selected for the divertor exhaust of the international nuclear fusion experiment ITER. In this harsh environment, the interactions of heat loads and ion fluxes with W can induce temporary or permanent evolution in the opt
Externí odkaz:
https://doaj.org/article/73dbb22bae8b4174bcdec74de7787716
Autor:
Nerina Dodic, Nicolas Ancellin, Morgane Bordessoules, Anne Bouillot, Nathan Butin, Cedric Charrier, Marie-Helene Fouchet, Alain Laroze, Anne-Pascale Luzy, Alexandre Moquette, Julia Pilot, Guillaume Serin, Jean-François Mirjolet, Fabrice Viviani, Christophe Parsy
Publikováno v:
Cancer Research. 82:1398-1398
Small molecule macrocyclic kinase inhibitors have attracted significant attention in drug discovery over the past years with drugs approval such as lorlatinib demonstrating the clinical relevance of this approach. We developed our expertise to furthe
Autor:
Guillaume Serin, Bjarte Mortensen, John S. Svendsen, Øystein Rekdal, Ketil André Camilio, Liv Tone Eliassen, Kristel Berg, Bengt Erik Haug, Jean-Francois Mirjolet, Wenche Stensen, Francis Bichat
Publikováno v:
Journal of Medicinal Chemistry. 59:2918-2927
Oncolytic immunotherapies represent a new promising strategy in the treatment of cancer. In our efforts to develop oncolytic peptides, we identified a series of chemically modified 9-mer cationic peptides that were highly effective against both drug-
Autor:
Marie-Claude Viaud-Massuard, Ludovic Juen, Ambrine Sahal, Jean-François Mirjolet, Camille Martin, Ofelia Feuillâtre, Pascal Grondin, Audrey Desgranges, Audrey Bertaux, Camille Gély, Guillaume Serin, Samira Benhamouche-Trouillet, Christine B. Baltus
Publikováno v:
Cancer Research. 80:4115-4115
Introduction: The Antibody-Drug Conjugates (ADCs)-based therapy has revealed a field of perspectives by increasing the specificity and the efficacy of the anti-tumoral drug treatment. McSAF is a company focused in bio-organic and bioconjugates chemis
Autor:
Damienne Bajon, Anne-Françoise Mingotaud, Véronique Gernigon, Guillaume Serin, Christophe Coudret, Jean-Daniel Marty, Thierry Soulet, Jean-Claude Micheau, Hong Hanh Nguyen, Sebastien Massenot
Publikováno v:
Journal of Physical Chemistry B
Journal of Physical Chemistry B, American Chemical Society, 2016, 120 (36), pp.9778-9787. ⟨10.1021/acs.jpcb.6b06859⟩
Journal of Physical Chemistry B, 2016, 120 (36), pp.9778-9787. ⟨10.1021/acs.jpcb.6b06859⟩
Journal of Physical Chemistry B, American Chemical Society, 2016, 120 (36), pp.9778-9787. ⟨10.1021/acs.jpcb.6b06859⟩
Journal of Physical Chemistry B, 2016, 120 (36), pp.9778-9787. ⟨10.1021/acs.jpcb.6b06859⟩
The behavior of highly concentrated aqueous solutions of two thermoresponsive polymers poly(N-isopropylacrylamide) (PNIPAm) and poly(N-vinylcaprolactam) (PVCL) have been investigated by terahertz time-domain spectroscopy (THz-TDS). Measurements have
Autor:
Andrew Tsotinis, Stavroula Georgakopoulou, Stefanos Riganas, Jean-François Mirjolet, Maria Theodoropoulou, Margarita Prassa, Vassilios I. Moutsos, Andreas Eleutheriades, Guillaume Serin, Alexandre Vamvakides, Humaira Khan, Angeliki Zaniou, Athanasios Mantelas, Ioannis Papanastasiou, George B. Foscolos, Kostas Dimas, Stavroula Pondiki, Vassilios N. Kourafalos
Publikováno v:
Journal of Medicinal Chemistry. 55:10241-10261
The synthesis of the adamantane phenylalkylamines 2a-d, 3a-c, and 4a-e is described. These compounds exhibited significant antiproliferative activity, in vitro, against eight cancer cell lines tested. The σ(1), σ(2), and sodium channel binding affi
Autor:
Andrew Tsotinis, Margarita Prassa, Guillaume Serin, Ioannis Papanastasiou, Humaira Khan, Stavroula Georgakopoulou, Vassilios I. Moutsos, Jean-Jacques Bourguignon, Jean-François Mirjolet, Vassilios N. Kourafalos, Angeliki Zaniou, Alexandre Vamvakides, Stavroula Pondiki, Stefanos Riganas, Andreas Eleutheriades, George B. Foscolos, Kostas Dimas, Maria Theodoropoulou
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:3323-3331
The synthesis of N-{4-[a-(1-adamantyl)benzyl]phenyl}piperazines 2a-e is described. The in vitro antiproliferative activity of most compounds against main cancer cell lines is significant. The σ(1), σ(2)-receptors and sodium channels binding affinit
Autor:
Jean-François Mirjolet, Florent Potvain, Raphaelle Guillard-Huet, Guillaume Serin, Didier Grillot, Akanksha Gangar, Eric Boursier
Publikováno v:
Cancer Research. 78:782-782
Immunological cell death (ICD) is a form of cancer cell death induced by radiotherapy, photodynamic therapy and a few chemotherapeutic agents such as Doxorubicin, Mitoxantrone, and Oxaliplatin. Unlike apoptosis or necrosis, ICD can induce an effectiv
Autor:
Franck Bourrat, Jean-Stéphane Joly, Violette Thermes, Eva Candal, Guillaume Serin, Alessandro Alunni
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2006, 133 (10), pp.1881-1890
Development (Cambridge, England), Company of Biologists, 2006, 133 (10), pp.1881-90. ⟨10.1242/dev.02350⟩
Development (Cambridge, England), Company of Biologists, 2006, 133 (10), pp.1881-1890
Development (Cambridge, England), Company of Biologists, 2006, 133 (10), pp.1881-90. ⟨10.1242/dev.02350⟩
The identification of genes that regulate proliferation is of great importance to developmental biology, regenerative medicine and cancer research. Using an in situ screen on a cortical structure of the medaka fish brain, we identified the simplet ge
Publikováno v:
Cell. 106(5):607-617
Nonsense-mediated decay (NMD) eliminates mRNAs that prematurely terminate translation. We used antibody to the nuclear cap binding protein CBP80 or its cytoplasmic counterpart eIF4E to immunopurify RNP containing nonsense-free or nonsense-containing