Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Guillaume, Martinez"'
Autor:
Mélusine Monrose, Hélène Holota, Guillaume Martinez, Christelle Damon‐Soubeyrand, Laura Thirouard, Emmanuelle Martinot, Edwige Battistelli, Angélique deHaze, Stéphanie Bravard, Christelle Tamisier, Françoise Caira, Charles Coutton, Anne‐Laure Barbotin, Angèle Boursier, Laila Lakhal, Claude Beaudoin, David H. Volle
Publikováno v:
Advanced Science, Vol 11, Iss 43, Pp n/a-n/a (2024)
Abstract Male sexual function can be disrupted by exposure to exogenous compounds that cause testicular physiological alterations. The constitutive androstane receptor (Car) is a receptor for both endobiotics and xenobiotics involved in detoxificatio
Externí odkaz:
https://doaj.org/article/5c0cfff5dc2646119bde8165b727621e
Autor:
Jana Muroňová, Zine Eddine Kherraf, Elsa Giordani, Emeline Lambert, Simon Eckert, Caroline Cazin, Amir Amiri-Yekta, Magali Court, Geneviève Chevalier, Guillaume Martinez, Yasmine Neirijnck, Francoise Kühne, Lydia Wehrli, Nikolai Klena, Virginie Hamel, Lisa De Macedo, Jessica Escoffier, Paul Guichard, Charles Coutton, Selima Fourati Ben Mustapha, Mahmoud Kharouf, Anne-Pacale Bouin, Raoudha Zouari, Nicolas Thierry-Mieg, Serge Nef, Stefan Geimer, Corinne Loeuillet, Pierre F Ray, Christophe Arnoult
Publikováno v:
eLife, Vol 12 (2024)
From a cohort of 167 infertile patients suffering from multiple morphological abnormalities of the flagellum (MMAF), pathogenic bi-allelic mutations were identified in the CCDC146 gene. In somatic cells, CCDC146 is located at the centrosome and at mu
Externí odkaz:
https://doaj.org/article/078af173188c4adb858332ae057a3a05
Autor:
Denis Dacheux, Guillaume Martinez, Christine E Broster Reix, Julie Beurois, Patrick Lores, Magamba Tounkara, Jean-William Dupuy, Derrick Roy Robinson, Corinne Loeuillet, Emeline Lambert, Zeina Wehbe, Jessica Escoffier, Amir Amiri-Yekta, Abbas Daneshipour, Seyedeh-Hanieh Hosseini, Raoudha Zouari, Selima Fourati Ben Mustapha, Lazhar Halouani, Xiaohui Jiang, Ying Shen, Chunyu Liu, Nicolas Thierry-Mieg, Amandine Septier, Marie Bidart, Véronique Satre, Caroline Cazin, Zine Eddine Kherraf, Christophe Arnoult, Pierre F Ray, Aminata Toure, Mélanie Bonhivers, Charles Coutton
Publikováno v:
eLife, Vol 12 (2023)
Male infertility is common and complex, presenting a wide range of heterogeneous phenotypes. Although about 50% of cases are estimated to have a genetic component, the underlying cause often remains undetermined. Here, from whole-exome sequencing on
Externí odkaz:
https://doaj.org/article/2b37a6175cab4e93a36110639ca35769
Autor:
Guillaume Martinez
Publikováno v:
Bio-Protocol, Vol 12, Iss 20 (2022)
Infertility has become a major public health problem, with a male factor involved in about half the cases. Mice are the most widely used animal model in reproductive biology research laboratories, but changes in sperm parameters in mice can be subtle
Externí odkaz:
https://doaj.org/article/02296741548840a385e24e0fad7dd189
Autor:
Guillaume Martinez, Charles Coutton, Corinne Loeuillet, Caroline Cazin, Jana Muroňová, Magalie Boguenet, Emeline Lambert, Magali Dhellemmes, Geneviève Chevalier, Jean-Pascal Hograindleur, Charline Vilpreux, Yasmine Neirijnck, Zine-Eddine Kherraf, Jessica Escoffier, Serge Nef, Pierre F Ray, Christophe Arnoult
Publikováno v:
eLife, Vol 11 (2022)
Male infertility is an important health concern that is expected to have a major genetic etiology. Although high-throughput sequencing has linked gene defects to more than 50% of rare and severe sperm anomalies, less than 20% of common and moderate f
Externí odkaz:
https://doaj.org/article/50542f6b588b43b1b940b0989e0ff1de
Autor:
Francesco Manfrevola, Guillaume Martinez, Charles Coutton, Domenico Rocco, Karine Reynaud, Yves Le Vern, Pascal Froment, Linda Beauclair, Denise Aubert, Riccardo Pierantoni, Rosanna Chianese, Florian Guillou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Ankyrin proteins (ANKRD) are key mediators linking membrane and sub-membranous cytoskeletal proteins. Recent findings have highlighted a new role of ANKRD31 during spermatogenesis, elucidating its involvement in meiotic recombination and male germ ce
Externí odkaz:
https://doaj.org/article/72516afd023148dc8113f3a40a111e02
Autor:
Anna Lamotte, Guillaume Martinez, Françoise Devillard, Jean-Pascal Hograindleur, Véronique Satre, Charles Coutton, Radu Harbuz, Florence Amblard, James Lespinasse, Mehdi Benchaib, Julien Bessonnat, Sophie Brouillet, Sylviane Hennebicq
Publikováno v:
Basic and Clinical Andrology, Vol 28, Iss 1, Pp 1-11 (2018)
Résumé Contexte Le mode de ségrégation chromosomique le plus fréquemment observé chez les patients porteurs de translocation robertsonienne est. un mode équilibré. Les données semblent varier peu selon la translocation analysée. La relative
Externí odkaz:
https://doaj.org/article/f539ff76fb6c4492ac5dedf16e72b95f
Autor:
Marie Christou‐Kent, Zine‐Eddine Kherraf, Amir Amiri‐Yekta, Emilie Le Blévec, Thomas Karaouzène, Béatrice Conne, Jessica Escoffier, Said Assou, Audrey Guttin, Emeline Lambert, Guillaume Martinez, Magalie Boguenet, Selima Fourati Ben Mustapha, Isabelle Cedrin Durnerin, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Charles Coutton, Nicolas Thierry‐Mieg, Serge Nef, Serge P Bottari, Raoudha Zouari, Jean Paul Issartel, Pierre F Ray, Christophe Arnoult
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 5, Pp 1-24 (2018)
Abstract The genetic causes of oocyte meiotic deficiency (OMD), a form of primary infertility characterised by the production of immature oocytes, remain largely unexplored. Using whole exome sequencing, we found that 26% of a cohort of 23 subjects w
Externí odkaz:
https://doaj.org/article/2a2704a3d4124064a7b9b19a154a9916
Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human
Autor:
Charles Coutton, Alexandra S. Vargas, Amir Amiri-Yekta, Zine-Eddine Kherraf, Selima Fourati Ben Mustapha, Pauline Le Tanno, Clémentine Wambergue-Legrand, Thomas Karaouzène, Guillaume Martinez, Serge Crouzy, Abbas Daneshipour, Seyedeh Hanieh Hosseini, Valérie Mitchell, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Jean-François Deleuze, Anne Boland, Sylviane Hennebicq, Véronique Satre, Pierre-Simon Jouk, Nicolas Thierry-Mieg, Beatrice Conne, Denis Dacheux, Nicolas Landrein, Alain Schmitt, Laurence Stouvenel, Patrick Lorès, Elma El Khouri, Serge P. Bottari, Julien Fauré, Jean-Philippe Wolf, Karin Pernet-Gallay, Jessica Escoffier, Hamid Gourabi, Derrick R. Robinson, Serge Nef, Emmanuel Dulioust, Raoudha Zouari, Mélanie Bonhivers, Aminata Touré, Christophe Arnoult, Pierre F. Ray
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Asthenozoospermia is a major cause of male infertility, and multiple morphological abnormalities of the flagella (MMAF) is a particularly severe form. Here, using whole-exome sequencing of 78 MMAF patients, the authors identify mutations in two WDR p
Externí odkaz:
https://doaj.org/article/03b883f351d94cb6999191bf43221e62
Autor:
Maegan E. Boutot, Brian W. Whitcomb, Nadia Abdelouahab, Andrea A. Baccarelli, Amélie Boivin, Artuela Caku, Virginie Gillet, Guillaume Martinez, Jean-Charles Pasquier, Jiping Zhu, Larissa Takser, Lindsay St-Cyr, Alexander Suvorov
Publikováno v:
Metabolites, Vol 11, Iss 10, p 657 (2021)
Animal studies have shown that developmental exposures to polybrominated diphenyl ethers (PBDE) permanently affect blood/liver balance of lipids. No human study has evaluated associations between in utero exposures to persistent organic pollutants (P
Externí odkaz:
https://doaj.org/article/8e41a6d212f7408daa0bd30ad9cd914b