Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Guillaume, Jacquemet"'
Autor:
Johanna Lilja, Jasmin Kaivola, James R. W. Conway, Joni Vuorio, Hanna Parkkola, Pekka Roivas, Michal Dibus, Megan R. Chastney, Taru Varila, Guillaume Jacquemet, Emilia Peuhu, Emily Wang, Ulla Pentikäinen, Itziar Martinez D. Posada, Hellyeh Hamidi, Arafath K. Najumudeen, Owen J. Sansom, Igor L. Barsukov, Daniel Abankwa, Ilpo Vattulainen, Marko Salmi, Johanna Ivaska
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The KRAS oncogene drives many common and highly fatal malignancies. These include pancreatic, lung, and colorectal cancer, where various activating KRAS mutations have made the development of KRAS inhibitors difficult. Here we identify the s
Externí odkaz:
https://doaj.org/article/aab4a06c715b4e4481e20d3e6037ab7e
Autor:
Estibaliz Gómez-de-Mariscal, Hanna Grobe, Joanna W Pylvänäinen, Laura Xénard, Ricardo Henriques, Jean-Yves Tinevez, Guillaume Jacquemet
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002740 (2024)
In life sciences, tracking objects from movies enables researchers to quantify the behavior of single particles, organelles, bacteria, cells, and even whole animals. While numerous tools now allow automated tracking from video, a significant challeng
Externí odkaz:
https://doaj.org/article/50ab8682fe95494880f7a166e182d85b
Autor:
Christoph Spahn, Estibaliz Gómez-de-Mariscal, Romain F. Laine, Pedro M. Pereira, Lucas von Chamier, Mia Conduit, Mariana G. Pinho, Guillaume Jacquemet, Séamus Holden, Mike Heilemann, Ricardo Henriques
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
DeepBacs guides users without expertise in machine learning methods to leverage state-of-the-art artificial neural networks to analyse bacterial microscopy images.
Externí odkaz:
https://doaj.org/article/19fbd4827d134373b89f42b5d1bcdbc7
Autor:
Lucas von Chamier, Romain F. Laine, Johanna Jukkala, Christoph Spahn, Daniel Krentzel, Elias Nehme, Martina Lerche, Sara Hernández-Pérez, Pieta K. Mattila, Eleni Karinou, Séamus Holden, Ahmet Can Solak, Alexander Krull, Tim-Oliver Buchholz, Martin L. Jones, Loïc A. Royer, Christophe Leterrier, Yoav Shechtman, Florian Jug, Mike Heilemann, Guillaume Jacquemet, Ricardo Henriques
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Deep learning methods show great promise for the analysis of microscopy images but there is currently an accessibility barrier to many users. Here the authors report a convenient entry-level deep learning platform that can be used at no cost: ZeroCos
Externí odkaz:
https://doaj.org/article/71c9afaf6b9849e787693c838589c312
Autor:
Mitro Miihkinen, Max L.B. Grönloh, Ana Popović, Helena Vihinen, Eija Jokitalo, Benjamin T. Goult, Johanna Ivaska, Guillaume Jacquemet
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109716- (2021)
Summary: Filopodia assemble unique integrin-adhesion complexes to sense the extracellular matrix. However, the mechanisms of integrin regulation in filopodia are poorly defined. Here, we report that active integrins accumulate at the tip of myosin-X
Externí odkaz:
https://doaj.org/article/58b81ee3731645c28b9246624729fde9
Autor:
Aki Stubb, Camilo Guzmán, Elisa Närvä, Jesse Aaron, Teng-Leong Chew, Markku Saari, Mitro Miihkinen, Guillaume Jacquemet, Johanna Ivaska
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregat
Externí odkaz:
https://doaj.org/article/054ff7d405564aaf959a9efd06915fc4
Autor:
Elnaz Fazeli, Nathan H. Roy, Gautier Follain, Romain F. Laine, Lucas von Chamier, Pekka E. Hänninen, John E. Eriksson, Jean-Yves Tinevez, Guillaume Jacquemet
Publikováno v:
F1000Research, Vol 9 (2020)
The ability of cells to migrate is a fundamental physiological process involved in embryonic development, tissue homeostasis, immune surveillance, and wound healing. Therefore, the mechanisms governing cellular locomotion have been under intense scru
Externí odkaz:
https://doaj.org/article/dc0615b3c30149aa8c4230c5fcf6dde1
Autor:
Elnaz Fazeli, Nathan H. Roy, Gautier Follain, Romain F. Laine, Lucas von Chamier, Pekka E. Hänninen, John E. Eriksson, Jean-Yves Tinevez, Guillaume Jacquemet
Publikováno v:
F1000Research, Vol 9 (2020)
The ability of cells to migrate is a fundamental physiological process involved in embryonic development, tissue homeostasis, immune surveillance, and wound healing. Therefore, the mechanisms governing cellular locomotion have been under intense scru
Externí odkaz:
https://doaj.org/article/88240937dae74545a5c10ba4682d6b83
Autor:
Guillaume Jacquemet, Habib Baghirov, Maria Georgiadou, Harri Sihto, Emilia Peuhu, Pierre Cettour-Janet, Tao He, Merja Perälä, Pauliina Kronqvist, Heikki Joensuu, Johanna Ivaska
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Filopodia have a prominent role in driving cancer cell invasion. Here, the authors show that L-type calcium channels are a druggable target regulating filopodia stability and maturation into focal adhesions in metastatic breast cancer cells.
Externí odkaz:
https://doaj.org/article/c0c5390a16a0498f861b5ea72324fa6a
Autor:
Guillaume Jacquemet, Alexandre Carisey, Diogo M. Cunha, Pieta Mattila, Luqman Awoniyi, PhD, Sara Hernández-Pérez
The immune synapse (IS) is a cell-cell interaction platform critical in lymphocyte activation by specific antigens. Despite of B cells being able to also respond to soluble antigens, in particular thein vivoimportance of the IS and surface-tethered a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3877458a0ec884d0ba5d2ae34fa32b81
https://doi.org/10.1101/2023.02.23.529674
https://doi.org/10.1101/2023.02.23.529674
