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Effective immunity and second waves: a dynamic causal modelling study [version 2; peer review: 2 approved]

Autor: Karl J. Friston, Thomas Parr, Peter Zeidman, Adeel Razi, Guillaume Flandin, Jean Daunizeau, Oliver J. Hulme, Alexander J. Billig, Vladimir Litvak, Cathy J. Price, Rosalyn J. Moran, Anthony Costello, Deenan Pillay, Christian Lambert

Publikováno v: Wellcome Open Research, Vol 5 (2020)

This technical report addresses a pressing issue in the trajectory of the coronavirus outbreak; namely, the rate at which effective immunity is lost following the first wave of the pandemic. This is a crucial epidemiological parameter that speaks to

Externí odkaz: https://doaj.org/article/2400d2d45c0d43b1844ab473171175d5

Multimodal Integration of M/EEG and f/MRI Data in SPM12

Autor: Richard N. Henson, Hunar Abdulrahman, Guillaume Flandin, Vladimir Litvak

Publikováno v: Frontiers in Neuroscience, Vol 13 (2019)

We describe the steps involved in analysis of multi-modal, multi-subject human neuroimaging data using the SPM12 free and open source software (https://www.fil.ion.ucl.ac.uk/spm/) and a publically-available dataset organized according to the Brain Im

Externí odkaz: https://doaj.org/article/e68736d4ec444632b7da7a155bfa9df6

Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells

Autor: Johan Vad-Nielsen, Nicklas Heine Staunstrup, Magnus Lindkvist Kjeldsen, Nina Dybdal, Guillaume Flandin, Claudia De Stradis, Tina Fuglsang Daugaard, Trine Vilsbøll-Larsen, Christoffer Trier Maansson, Thomas Koed Doktor, Boe Sandahl Sorensen, Anders Lade Nielsen

Publikováno v: Vad-Nielsen, J, Staunstrup, N H, Lindkvist Kjeldsen, M, Dybdal, N, Flandin, G, Stradis, C D, Daugaard, T F, Larsen, T V, Månsson, C T, Doktor, T K, Sørensen, B S & Nielsen, A L 2023, ' Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells ', Translational lung cancer research, vol. 12, no. 1 . https://doi.org/10.21037/tlcr-22-507
Vad-Nielsen, J, Staunstrup, N H, Kjeldsen, M L, Dybdal, N, Flandin, G, De Stradis, C, Daugaard, T F, Vilsbøll-Larsen, T, Maansson, C T, Doktor, T K, Sorensen, B S & Nielsen, A L 2023, ' Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells ', Translational Lung Cancer Research, vol. 12, no. 1, pp. 42-65 . https://doi.org/10.21037/tlcr-22-507

Background: Epithelial-mesenchymal-transition (EMT) is an epigenetic-based mechanism contributing to the acquired treatment resistance against receptor tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) cells harboring epidermal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6665931436c97e3e6930673adc22089
https://pure.au.dk/portal/da/publications/genomewide-epigenetic-and-mrnaexpression-profiling-followed-by-crisprcas9mediated-genedisruptions-corroborate-the-mir141mir200czeb1zeb2fgfr1-axis-in-acquired-emtassociated-egfr-tkiresistance-in-nsclc-cells(9decfe67-cb15-497b-989f-d40dc19275a6).html

Neurodesk: An accessible, flexible, and portable data analysis environment for reproducible neuroimaging

Autor: Angela I. Renton, Thanh Thuy Dao, David F. Abbott, Toluwani J Amos, Saskia Bollmann, Andy Botting, Megan E. J. Campbell, Jeryn Chang, Oren Civier, Thomas G. Close, Korbinian Eckstein, Gary F. Egan, Stefanie Evas, Guillaume Flandin, Kelly G. Garner, Marta I. Garrido, Satrajit S Ghosh, Martin Grignard, Anthony J. Hannan, Renzo Huber, Matthew E Hughes, Tom Johnstone, Jakub R. Kaczmarzyk, Lars Kasper, Levin Kuhlmann, Kexin Lou, Paris Lyons, Yorguin-Jose Mantilla-Ramos, Jason B. Mattingley, Jo Morris, Akshaiy Narayanan, Franco Pestilli, Aina Puce, Fernanda L. Ribeiro, Nigel C. Rogasch, Chris Rorden, Mark Schira, Thomas B. Shaw, Benjamin M Slade, Gershon Spitz, Ashley Stewart, Ryan P. Sullivan, David J. White, Xincheng Ye, Judy D. Zhu, Aswin Narayanan, Steffen Bollmann

Neuroimaging data analysis often requires purpose-built software, which can be challenging to install and may produce different results across computing environments. Beyond being a roadblock to neuroscientists, these issues of accessibility and port

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::146c0336736eb2675bfbce86f447d7b0
https://doi.org/10.1101/2022.12.23.521691