Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Guillaume, Bollot"'
Autor:
Gabriel, Watkinson, Ethan, Cohen, Nicolas, Bourriez, Ihab, Bendidi, Guillaume, Bollot, Auguste, Genovesio
With the surge in available data from various modalities, there is a growing need to bridge the gap between different data types. In this work, we introduce a novel approach to learn cross-modal representations between image data and molecular repres
Externí odkaz:
http://arxiv.org/abs/2311.04678
Autor:
Ihab Bendidi, Adrien Bardes, Ethan Cohen, Alexis Lamiable, Guillaume Bollot, Auguste Genovesio
Publikováno v:
Biological Imaging, Vol 4 (2024)
Self-supervised representation learning (SSRL) in computer vision relies heavily on simple image transformations such as random rotation, crops, or illumination to learn meaningful and invariant features. Despite acknowledged importance, there is a l
Externí odkaz:
https://doaj.org/article/18327d795d664acdb1a7181699760c4a
Autor:
Aixiao Li, Ahmed Bouhss, Marie-Jeanne Clément, Cyril Bauvais, J. Paul Taylor, Guillaume Bollot, David Pastré
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
In recent years, RNA has gained traction both as a therapeutic molecule and as a therapeutic target in several human pathologies. In this review, we consider the approach of targeting RNA using small molecules for both research and therapeutic purpos
Externí odkaz:
https://doaj.org/article/22c47e5584934302a02e842601707265
Autor:
Ethan Cohen, Maxime Corbe, Cláudio A. Franco, Francisca F. Vasconcelos, Franck Perez, Elaine Del Nery, Guillaume Bollot, Auguste Genovesio
Publikováno v:
Biological Imaging, Vol 3 (2023)
Drug discovery uses high throughput screening to identify compounds that interact with a molecular target or that alter a phenotype favorably. The cautious selection of molecules used for such a screening is instrumental and is tightly related to the
Externí odkaz:
https://doaj.org/article/85d3f2e86ce640d79c502ef9afe3ca38
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783031250682
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bfc73b80e17ca6869ad03684f986ee8
https://doi.org/10.1007/978-3-031-25069-9_26
https://doi.org/10.1007/978-3-031-25069-9_26
Autor:
Ethan Cohen, Maxime Corbe, Cláudio A. Franco, Francisca F. Vasconcelos, Franck Perez, Elaine Del Nery, Guillaume Bollot, Auguste Genovesio
Drug discovery uses high throughput screening to identify compounds that interact with a molecular target or that alter a phenotype favorably. The cautious selection of molecules used for such a screening is instrumental and is tightly related to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9c048f2425198c73546216bde52ad9
https://doi.org/10.1101/2022.10.24.513564
https://doi.org/10.1101/2022.10.24.513564
Autor:
Camille Hauguel, Sarah Ducellier, Olivier Provot, Nada Ibrahim, Diana Lamaa, Coline Balcerowiak, Boris Letribot, Megane Nascimento, Vincent Blanchard, Laurie Askenatzis, Helene Levaique, Jérôme Bignon, Francesco Baschieri, Cyril Bauvais, Guillaume Bollot, Dolor Renko, Alain Deroussent, Bastien Prost, Marie-Catherine Laisne, Sophie Michallet, Laurence Lafanechère, Sébastien Papot, Guillaume Montagnac, Christine Tran, Mouad Alami, Sebastien Apcher, Abdallah Hamze
Publikováno v:
European Journal of Medicinal Chemistry. 240:114573
A series of quinoline and quinazoline analogs were designed and synthesized as new tubulin polymerization (TP) and histone deacetylases (HDAC) inhibitors. Compounds 12a and 12d showed the best cytotoxicity activities against a panel of human cancer c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7336a68864efb3226acaab439909276
https://doi.org/10.1016/j.ejmech.2022.114573
https://doi.org/10.1016/j.ejmech.2022.114573
Autor:
David Pastré, Guillaume Bollot, Alexandre Maucuer, Jean de Matha Salone, Marie-Jeanne Clément, Pierrick Craveur, Krystel El Hage, Asaki Kobayashi
Publikováno v:
FEBS Journal
FEBS Journal, 2021, 289 (3), pp.682-698. ⟨10.1111/febs.16199⟩
FEBS Journal, Wiley, 2021, ⟨10.1111/febs.16199⟩
FEBS Journal, 2021, 289 (3), pp.682-698. ⟨10.1111/febs.16199⟩
FEBS Journal, Wiley, 2021, ⟨10.1111/febs.16199⟩
International audience; Splicing factor mutations are frequent in myeloid neoplasms, blood cancers,and solid tumors. Cancer cells harboring these mutations present aparticular vulnerability to drugs that target splicing factors such asSF3b155 or CAPE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9765a038e49a4490e92d62339a1630f6
https://hal.science/hal-03354012
https://hal.science/hal-03354012
Autor:
Alexandre Maucuer, David Pastré, Guillaume Bollot, Pierrick Craveur, Asaki Kobayashi, Krystel El Hage, Jean de Matha Salone, Marie-Jeanne Clément
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a1456ea8861b7d56a9d07218f80961a
https://doi.org/10.1111/febs.16199/v2/response1
https://doi.org/10.1111/febs.16199/v2/response1
Autor:
Claude Hercend, Cyril Bauvais, Guillaume Bollot, Nicolas Delacotte, Philippe Chappuis, France Woimant, Jean-Marie Launay, Philippe Manivet
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26245 (2011)
The diagnostic of orphan genetic disease is often a puzzling task as less attention is paid to the elucidation of the pathophysiology of these rare disorders at the molecular level. We present here a multidisciplinary approach using molecular modelin
Externí odkaz:
https://doaj.org/article/5b1f2f3efb1741888e3f06da6b1635ad