Optimized DNA vaccines to specifically induce therapeutic CD8 T cell responses against autochthonous breast tumors

Autor: Esteban Celis, Guilian Niu, Norma Bradley, Hyun Il Cho

Publikováno v: Cancer Immunology, Immunotherapy. 57:1695-1703

Vaccines capable of inducing CD8 T cell responses to antigens expressed by tumor cells are considered as attractive choices for the treatment and prevention of malignant diseases. Our group has previously reported that immunization with synthetic pep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f61f55cbb95ab1b1369e6474128771
https://doi.org/10.1007/s00262-008-0465-x

List of Contributors

Autor: Paulo Abdo do Seixo Kadri, Matthew A. Adamo, Jennifer Adamski, Osama Al-Mefty, Arif N. Ali, Kristian Aquilina, James A. Balogun, Garni Barkhoudarian, Ute Bartels, Wenya Linda Bi, Eric Bouffet, Julie A. Bradley, Henry Brem, Paolo Cappabianca, Ricardo L. Carrau, William T. Couldwell, Walter J. Curran, Maria Laura Del Basso De Caro, Dale Ding, Alberto Di Somma, Leo F.S. Ditzel Filho, Brian J. Dlouhy, Ian F. Dunn, James J. Evans, Manuel Ferreira, David P. Friedman, Takeshi Funaki, Ashish R. Gandhe, Ravi H. Gandhi, M. Reid Gooch, Daniel J. Indelicato, George Jallo, Ali O. Jamshidi, John Jane, Rachel Jimenez, David Jones, Daniel F. Kelly, Tyler J. Kenning, Edward E. Kerr, Irene Kim, Anne Klibanski, Douglas Kondziolka, Khaled M. Krisht, Edward R. Laws, Cheng-Chia Lee, Robert G. Louis, L. Dade Lunsford, Shannon M. MacDonald, Alessandra Mantovani, Konstantinos Margetis, Luigi Maria Cavallo, Carolina Martins, Heather J. McCrea, Gautam U. Mehta, Edward A. Monaco, Hermann L. Müller, Ajay Niranjan, Guilian Niu, Edward H. Oldfield, Bradley A. Otto, Troy D. Payner, Maria Peris-Celda, Carlos D. Pinheiro-Neto, Daniel M. Prevedello, Jiang Qian, Albert L. Rhoton, Benjamin A. Rubin, James T. Rutka, Theodore H. Schwartz, Laligam N. Sekhar, Robert C. Sergott, Roshan V. Sethi, Jason P. Sheehan, Eugenia Shekhtman, Walavan Sivakumar, Domenico Solari, Mark Souweidane, Zachary Tempel, Charles Teo, Philip V. Theodosopoulos, Dominic Thompson, Nicholas A. Tritos, Rafael Uribe, Rowan Valentine, Hung Tzu Wen, Jeffrey H. Wisoff, Anthony T. Yachnis, Tong Yang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9993add745ccfe4cfe47ed6bbce3d12e
https://doi.org/10.1016/b978-0-12-416706-3.01002-3

Role of Stat3 in Regulating p53 Expression and Function

Autor: Rosalyn B. Irby, Gabriela Wright, James G. Karras, Guilian Niu, Drew M. Pardoll, Yihong Ma, Jon Briggs, W. Douglas Cress, Hua Yu, Richard Jove, Kenneth L. Wright, Mei Huang, Jiangdong Chen

Publikováno v: Molecular and Cellular Biology. 25:7432-7440

Loss of p53 function by mutation is common in cancer. However, most natural p53 mutations occur at a late stage in tumor development, and many clinically detectable cancers have reduced p53 expression but no p53 mutations. It remains to be fully dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5b7443c80296d0371435f5844fa3ca
https://doi.org/10.1128/mcb.25.17.7432-7440.2005

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

Autor: Marcin Kortylewski, Kenneth H. Shain, Domenico Coppola, Richard Heller, William S. Dalton, Tianhong Wang, Hua Yu, Drew M. Pardoll, Guilian Niu, Lyudmila Burdelya, Richard Jove, Shumin M. Zhang, Dmitry I. Gabrilovich, Raka Bhattacharya

Publikováno v: Nature Medicine. 10:48-54

Although tumor progression involves processes such as tissue invasion that can activate inflammatory responses, the immune system largely ignores or tolerates disseminated cancers. The mechanisms that block initiation of immune responses during cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31c7849c41fbcfb422638e410acd15f
https://doi.org/10.1038/nm976

Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter

Autor: Dayami Lopez, W. Bradford Carter, Guilian Niu, Philippe Huber

Publikováno v: Archives of biochemistry and biophysics. 482(1-2)

Endothelial integrity is dependent on intracellular adherens junctions formed by complexes of vascular endothelial (VE)-cadherin and catenins. We have previously demonstrated that exposing endothelial cells (EC) to breast cancer cell-conditioned medi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2116efdac0f37442103b5b1f581c8f19
https://pubmed.ncbi.nlm.nih.gov/19046938