Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Guilhian Leipnitz"'
Autor:
Josyane de Andrade Silveira, Manuela Bianchin Marcuzzo, Jaqueline Santana da Rosa, Nathalia Simon Kist, Chrístofer Ian Hernandez Hoffmann, Andrey Soares Carvalho, Rafael Teixeira Ribeiro, André Quincozes-Santos, Carlos Alexandre Netto, Moacir Wajner, Guilhian Leipnitz
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1563 (2024)
3-Hydroxy-3-methylglutaric acidemia (HMGA) is a neurometabolic inherited disorder characterized by the predominant accumulation of 3-hydroxy-3-methylglutaric acid (HMG) in the brain and biological fluids of patients. Symptoms often appear in the firs
Externí odkaz:
https://doaj.org/article/4ffe427a0be546ca9c5764d07b9f144f
Autor:
Paula Michele da Silva Schmidt, Jéssica Puchalski Trettim, Aline Longoni, Mateus Grings, Mariana Bonati de Matos, Luciana de Avila Quevedo, Ana Paula Ardais, Fernanda Nedel, Gabriele Ghisleni, Guilhian Leipnitz, Ricardo Tavares Pinheiro, Adriano Martimbianco de Assis
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundSuicide risk is prominent among the problems affecting populations, mainly due to the broad family, psychosocial and economic impact. Most individuals at suicidal risk have some mental disorder. There is considerable evidence that psychiatr
Externí odkaz:
https://doaj.org/article/662e9e3c0eea46398f38dc06b4cf1203
Autor:
Carlos-Alberto Gonçalves, Patrícia Sesterheim, Krista M. Wartchow, Larissa Daniele Bobermin, Guilhian Leipnitz, André Quincozes-Santos
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
We are living in a terrifying pandemic caused by Sars-CoV-2, in which patients with diabetes mellitus have, from the beginning, been identified as having a high risk of hospitalization and mortality. This viral disease is not limited to the respirato
Externí odkaz:
https://doaj.org/article/7ea65697db0145ffa46c84b75858177a
Autor:
Nícolas Manzke Glänzel, Belisa Parmeggiani, Mateus Grings, Bianca Seminotti, Morgana Brondani, Larissa D. Bobermin, César A. J. Ribeiro, André Quincozes-Santos, Jerry Vockley, Guilhian Leipnitz
Publikováno v:
Cells, Vol 12, Iss 12, p 1557 (2023)
Sulfite predominantly accumulates in the brain of patients with isolated sulfite oxidase (ISOD) and molybdenum cofactor (MoCD) deficiencies. Patients present with severe neurological symptoms and basal ganglia alterations, the pathophysiology of whic
Externí odkaz:
https://doaj.org/article/ffe6e30328024464a374427db0517c37
Autor:
Yorran Hardman Araújo Montenegro, Geancarlo Zanatta, André Quincozes-Santos, Guilhian Leipnitz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/12e0ec5e1f7747daa98869e9e09f0aca
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/758b6344be8b4744a4803820b1005be5
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Inherited metabolic disorders (IMDs) are rare genetic conditions that affect multiple organs, predominantly the central nervous system. Since treatment for a large number of IMDs is limited, there is an urgent need to find novel therapeutical targets
Externí odkaz:
https://doaj.org/article/35e0b41a75c444569c68f800a18d11db
Autor:
Morgana Brondani, Ana Cristina Roginski, Rafael Teixeira Ribeiro, Maria Paula de Medeiros, Chrístofer Ian Hernandez Hoffmann, Moacir Wajner, Guilhian Leipnitz, Bianca Seminotti
Publikováno v:
Toxicology Letters. 381:48-59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a5588b99143a82343a8dbf4ec4c7e3a
https://doi.org/10.1016/j.toxlet.2023.04.011
https://doi.org/10.1016/j.toxlet.2023.04.011
Autor:
Pedro Arend Guazzelli, Giordano Fabricio Cittolin-Santos, Leo Anderson Meira-Martins, Mateus Grings, Yasmine Nonose, Gabriel S. Lazzarotto, Daniela Nogara, Jussemara S. da Silva, Fernanda U. Fontella, Moacir Wajner, Guilhian Leipnitz, Diogo O. Souza, Adriano Martimbianco de Assis
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2020)
Acute liver failure (ALF) implies a severe and rapid liver dysfunction that leads to impaired liver metabolism and hepatic encephalopathy (HE). Recent studies have suggested that several brain alterations such as astrocytic dysfunction and energy met
Externí odkaz:
https://doaj.org/article/06eaee487fd54ca08618e7adf26aa60e
Autor:
Vanessa Sovrani, Larissa Daniele Bobermin, Camila Leite Santos, Morgana Brondani, Carlos-Alberto Gonçalves, Guilhian Leipnitz, André Quincozes-Santos
Publikováno v:
Molecular and Cellular Biochemistry. 478:1205-1216
Aging is intrinsically related to metabolic changes and characterized by the accumulation of oxidative and inflammatory damage, as well as alterations in gene expression and activity of several signaling pathways, which in turn impact on homeostatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139fd92dcdc3808d28b2e7601093501f
https://doi.org/10.1007/s11010-022-04585-z
https://doi.org/10.1007/s11010-022-04585-z