Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Guilherme de Paula, Costa"'
Autor:
Ana Paula de Jesus Menezes, Milene Lopes da Silva, Wagner Luiz Pereira, Guilherme de Paula Costa, Aline Luciano Horta, Andréa Aparecida Santos Mendonça, Ana Claudia Alvarenga Carneiro, Debora Maria Soares de Souza, Rômulo Dias Novaes, Róbson Ricardo Teixeira, André Talvani
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 22, Iss , Pp 466-476 (2020)
Objective: Trypanosoma cruzi infection affects millions of people worldwide, and the drugs available for its treatment have limited efficacy. 1,8-Dioxooctahydroxanthenes and tetraketones are compounds with important biological applications. The aim o
Externí odkaz:
https://doaj.org/article/b19de0b4b0c3454da3e776b0e15439ec
Autor:
Natália Ivanova, Ana Luísa Junqueira Leite, Marcel Barbosa Vieira, Otto Henrique Cezar e Silva, Ludmilla Walter Reis Mota, Guilherme de Paula Costa, Cristiano Schetini de Azevedo, Sarah Alves Auharek, Romulo Dias Novaes, Kelerson Mauro de Castro Pinto, Rodrigo Fernando Bianchi, André Talvani
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The search for an effective etiologic treatment to eliminate Trypanosoma cruzi, the causative agent of Chagas disease, has continued for decades and yielded controversial results. In the 1970s, nifurtimox and benznidazole were introduced for clinical
Externí odkaz:
https://doaj.org/article/120be9fe3bcf4dc1bbd44ea12b8e95b9
Autor:
Frank Silva Bezerra, Camila de Oliveira Ramos, Thalles de Freitas Castro, Natália Pereira da Silva Araújo, Ana Beatriz Farias de Souza, Ana Carla Balthar Bandeira, Guilherme de Paula Costa, Christiane Teixeira Cartelle, André Talvani, Sílvia Dantas Cangussú, Laurent Brochard, Akinori Cardozo Nagato
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background In addition to the risk of developing ventilator-induced lung injury, patients with ARDS are at risk of developing hyperoxic injury due the supra-physiological oxygen supplementation clinically required to reverse hypoxemia. Alter
Externí odkaz:
https://doaj.org/article/bf68f8add78b49ef913678d2c4426008
Autor:
Débora Maria Soares de Souza, Maria Cláudia Silva, Silvia Elvira Barros Farias, Ana Paula de J. Menezes, Cristiane Maria Milanezi, Karine de P. Lúcio, Nívia Carolina N. Paiva, Paula Melo de Abreu, Daniela Caldeira Costa, Kelerson Mauro de Castro Pinto, Guilherme de Paula Costa, João Santana Silva, André Talvani
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background:Trypanosoma cruzi is a protozoan parasite that causes Chagas disease and affects 6–7 million people mainly in Latin America and worldwide. Here, we investigated the effects of hyperlipidic diets, mainly composed of olive oil or lard on e
Externí odkaz:
https://doaj.org/article/17e4f68814f84153aa87eaca58ef376e
Autor:
Stéfani Miranda-Castro, Felipe J. Aidar, Samara Silva de Moura, Lucas Marcucci-Barbosa, Lázaro Fernandes Lobo, Francisco de Assis Dias Martins-Júnior, Roberta da Silva Filha, Pedro Alves Soares Vaz de Castro, Ana Cristina Simões e Silva, Danielle da Glória de Souza, Siomara Aparecida da Silva, Kelerson Mauro de Castro Pinto, Guilherme de Paula Costa, Ana Filipa Silva, Filipe Manuel Clemente, William Valadares Campos Pereira, Albená Nunes-Silva
Publikováno v:
Biology, Vol 11, Iss 4, p 573 (2022)
Background: to evaluate the effects of one week of supplementation with curcumin combined with piperine on physical performance, immune system cell counts, muscle damage, and plasma levels of inflammatory markers after a treadmill running training se
Externí odkaz:
https://doaj.org/article/17e8c9f592684446a981fcfc601b5f88
Autor:
Kátia da Silva Fonseca, Luísa Perin, Nívia Carolina Nogueira de Paiva, Beatriz Cristiane da Silva, Thays Helena Chaves Duarte, Flávia de Souza Marques, Guilherme de Paula Costa, Israel Molina, Rodrigo Correa-Oliveira, Paula Melo de Abreu Vieira, Cláudia Martins Carneiro
Publikováno v:
Pathogens, Vol 10, Iss 6, p 729 (2021)
As the development of new drugs for Chagas disease is not a priority due to its neglected disease status, an option for increasing treatment adherence is to explore alternative treatment regimens, which may decrease the incidence of side effects. The
Externí odkaz:
https://doaj.org/article/50db52f0a3a34ad5a6b8e8d640dd002a
Autor:
Aline Luciano Horta, Vivian Paulino Figueiredo, Ana Luisa Junqueira Leite, Guilherme de Paula Costa, Ana Paula de Jesus Menezes, Camila de Oliveira Ramos, Tamiles Caroline Fernandes Pedrosa, Frank Silva Bezerra, Paula Melo de Abreu Vieira, André Talvani
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 113, Iss 11 (2018)
BACKGROUND The infection led by Trypanosoma cruzi persists in mammalian tissues causing an inflammatory imbalance. Carvedilol (Cv), a non-selective beta blocker drug indicated to treat heart failure and antihypertensive has shown to promote antioxida
Externí odkaz:
https://doaj.org/article/b3ffedc7f32e43d28e67fb972c87c29c
Autor:
Sílvia Dantas Cangussú, Ana Beatriz Farias de Souza, Frank Silva Bezerra, Thalles de Freitas Castro, Guilherme de Paula Costa, Daniela Fonseca Abdo Rocha, Pedro Alves Machado-Junior, André Talvani
Publikováno v:
BioMed Research International, Vol 2021 (2021)
BioMed Research International
BioMed Research International
Cigarette smoke (CS) is the major cause of preventable death worldwide, and it can also cause damage to extrapulmonary organs, such as the liver, mainly due the generation of reactive oxygen species (ROS). The liver is an essential organ for human su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11210042baeba5ed18843ce34c4f5a4
https://doi.org/10.1155/2021/7101313
https://doi.org/10.1155/2021/7101313
Autor:
Kelerson Mauro de Castro Pinto, Helen Hermana Miranda Hermsdorff, Júlia Cristina Cardoso Carraro, Lilian Maria Peixoto Lopes, Guilherme de Paula Costa, Emerson Cruz de Oliveira, Fernanda Guimarães Drummond e Silva, Daniel Barbosa Coelho, Lenice Kappes Becker, André Talvani
Publikováno v:
BioMed Research International, Vol 2021 (2021)
BioMed Research International
BioMed Research International
Habitual food intake and physical activity can affect chronic low-grade inflammation, which is common in the elderly, because of changes in the immune system and body composition. Thus, the present study proposes an evaluation of the influence of pas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2594a6c4571ef897d9f110088d7ece0
https://doi.org/10.1155/2021/6681823
https://doi.org/10.1155/2021/6681823
Autor:
Thalles de Freitas Castro, André Talvani, Frank Silva Bezerra, Leandro da Silva Cândido, Aline Maria dos Santos, Walter A. Zin, Guilherme de Paula Costa, Laisy Cristina de Paula, Natália Alves de Matos, Sílvia Dantas Cangussú
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Mechanical ventilation (MV) is essential for the treatment of critical patients since it may provide a desired gas exchange. However, MV itself can trigger ventilator-associated lung injury in patients. We hypothesized that the mechanisms of lung inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0ebea1f6c6c6ec907c0aa112beea4b
https://doi.org/10.1155/2021/5196896
https://doi.org/10.1155/2021/5196896