Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Guilherme Testa-Silva"'
Autor:
Joshua Obermayer, Tim S. Heistek, Amber Kerkhofs, Natalia A. Goriounova, Tim Kroon, Johannes C. Baayen, Sander Idema, Guilherme Testa-Silva, Jonathan J. Couey, Huibert D. Mansvelder
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Parvalbumin and somatostatin expressing interneurons mediate lateral inhibition between cortical neurons. Here the authors report the mechanisms by which acetylcholine from the basal forebrain selectively augments lateral inhibition via Martinotti ce
Externí odkaz:
https://doaj.org/article/3bb32f558e4e41c8984accb0680d2e97
Autor:
Guy Eyal, Matthijs B. Verhoog, Guilherme Testa-Silva, Yair Deitcher, Ruth Benavides-Piccione, Javier DeFelipe, Christiaan P. J. de Kock, Huibert D. Mansvelder, Idan Segev
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
We present detailed models of pyramidal cells from human neocortex, including models on their excitatory synapses, dendritic spines, dendritic NMDA- and somatic/axonal Na+ spikes that provided new insights into signal processing and computational cap
Externí odkaz:
https://doaj.org/article/17b62b6a092e44dfbfb424500128d161
Autor:
Guy Eyal, Matthijs B Verhoog, Guilherme Testa-Silva, Yair Deitcher, Johannes C Lodder, Ruth Benavides-Piccione, Juan Morales, Javier DeFelipe, Christiaan PJ de Kock, Huibert D Mansvelder, Idan Segev
Publikováno v:
eLife, Vol 5 (2016)
The advanced cognitive capabilities of the human brain are often attributed to our recently evolved neocortex. However, it is not known whether the basic building blocks of the human neocortex, the pyramidal neurons, possess unique biophysical proper
Externí odkaz:
https://doaj.org/article/53fda0d2124a41d7a6b60712c1a2039b
Autor:
Guilherme Testa-Silva, Matthijs B Verhoog, Daniele Linaro, Christiaan P J de Kock, Johannes C Baayen, Rhiannon M Meredith, Chris I De Zeeuw, Michele Giugliano, Huibert D Mansvelder
Publikováno v:
PLoS Biology, Vol 12, Iss 11, p e1002007 (2014)
Neuronal firing, synaptic transmission, and its plasticity form the building blocks for processing and storage of information in the brain. It is unknown whether adult human synapses are more efficient in transferring information between neurons than
Externí odkaz:
https://doaj.org/article/9d69cd699b934365ad539fdbc5d4baf5
Autor:
Sarah Hunt, Yoni Leibner, Eline J Mertens, Natalí Barros-Zulaica, Lida Kanari, Tim S Heistek, Mahesh M Karnani, Romy Aardse, René Wilbers, Djai B Heyer, Natalia A Goriounova, Matthijs B Verhoog, Guilherme Testa-Silva, Joshua Obermayer, Tamara Versluis, Ruth Benavides-Piccione, Philip de Witt-Hamer, Sander Idema, David P Noske, Johannes C Baayen, Ed S Lein, Javier DeFelipe, Henry Markram, Huibert D Mansvelder, Felix Schürmann, Idan Segev, Christiaan P J de Kock
Publikováno v:
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University Press
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246, https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University press
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University Press
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246, https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University press
Synaptic transmission constitutes the primary mode of communication between neurons. It is extensively studied in rodent but not human neocortex. We characterized synaptic transmission between pyramidal neurons in layers 2 and 3 using neurosurgically
Autor:
Guilherme Testa-Silva, Marius Rosier, Suraj Honnuraiah, Robertas Guzulaitis, Ana Morello Megias, Chris French, James King, Katharine Drummond, Lucy M. Palmer, Greg John Stuart
Publikováno v:
SSRN Electronic Journal.
Autor:
Guilherme Testa-Silva, Marius Rosier, Suraj Honnuraiah, Robertas Guzulaitis, Ana Morello Megias, Chris French, James King, Katharine Drummond, Lucy M. Palmer, Greg J. Stuart
Publikováno v:
Cell reports, Cambridge : Cell Press, 2022, vol. 41, no. 11, art. no. 111787, p. 1-14
Neurons receive synaptic input primarily onto their dendrites. While we know much about the electrical properties of dendrites in rodents, we have only just started to describe their properties in the human brain. Here, we investigate the capacity of
Autor:
Greg J. Stuart, Guilherme Testa-Silva, Christopher A. French, James King, Katharine J. Drummond, Ana Morello Megias, Lucy M. Palmer, Suraj Honnuraiah, Robertas Guzulaitis, Marius Rosier
SummaryNeurons receive synaptic input primarily onto their dendrites. While we know much about the electrical properties of dendrites in rodents, we have only just started to describe their properties in the human brain. Here we investigate the capac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a31e63de2aa7a9f0607ba1c56d1848
https://doi.org/10.1101/2021.10.22.465509
https://doi.org/10.1101/2021.10.22.465509
Autor:
Daan Brinks, F. Phil Brooks, Adam E. Cohen, Miao-Ping Chien, Benjamin Gmeiner, He Tian, Yoav Adam, Simon Kheifets, Guilherme Testa-Silva, William Bloxham
Publikováno v:
Science Advances, 7(19)
Science advances, 7(19):eabe3216. American Association for the Advancement of Science
Science Advances
Science advances, 7(19):eabe3216. American Association for the Advancement of Science
Science Advances
Photoactivated genetically encoded voltage indicators (GEVIs) have the potential to enable optically sectioned voltage imaging at the intersection of a photoactivation beam and an imaging beam. We developed a pooled high-throughput screen to identify
Autor:
Jörn Diedrichsen, Chris I. De Zeeuw, Martin I. Sereno, Mohamed Tachrount, Helen D'Arceuil, Guilherme Testa-Silva
Publikováno v:
Brain and Mind Institute Researchers' Publications
Proceedings of the National Academy of Sciences of the U.S.A., 117(32), 19538-19543. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117, 19538-19543. National Academy of Sciences
Proceedings of the National Academy of Sciences of the U.S.A., 117(32), 19538-19543. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117, 19538-19543. National Academy of Sciences
Significance The cerebellum has long been recognized as a partner of the cerebral cortex, and both have expanded greatly in human evolution. The thin cerebellar cortex is even more tightly folded than the cerebral cortex. By scanning a human cerebell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cbbe49235b4bac15af0f3e6a3b22cc
https://ir.lib.uwo.ca/brainpub/424
https://ir.lib.uwo.ca/brainpub/424