Výsledky vyhledávání - "Guilherme T. Voss"

Prospecting for a quinoline containing selenium for comorbidities depression and memory impairment induced by restriction stress in mice

Autor: Renata L. de Oliveira, Guilherme T. Voss, Karline da C. Rodrigues, Mikaela P. Pinz, Julia V. Biondi, Nicole P. Becker, Eduardo Blodorn, William B. Domingues, Allya Larroza, Vinícius F. Campos, Diego Alves, Ethel A. Wilhelm, Cristiane Luchese

Publikováno v: Psychopharmacology

Rationale Depression is often associated with memory impairment, a clinical feature of Alzheimer’s disease (AD), but no effective treatment is available. 7-Chloro-4-(phenylselanyl) quinoline (4-PSQ) has been studied in experimental models of diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebea461b2d789cd039232abef4a3275f
https://pubmed.ncbi.nlm.nih.gov/35013761

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Synthesis of chitosan derivatives with organoselenium and organosulfur compounds: Characterization, antimicrobial properties and application as biomaterials

Autor: Renata L. de Oliveira, Laura Abenante, Guilherme T. Voss, Cristiane Luchese, João M. Anghinoni, Ethel A. Wilhelm, André R. Fajardo, Eder J. Lenardão, Rodrigo de Almeida Vaucher, Matheus S. Gularte

Publikováno v: Carbohydrate Polymers. 219:240-250

In this study, Schiff bases of chitosan (CS) were synthesized using citronellal, citral, and their derivatives containing selenium and sulfur. Organoselenium and organosulfur compounds show attractive biological and pharmaceutical activities, which c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3822df58d67f28a21890b256ffee88
https://doi.org/10.1016/j.carbpol.2019.05.040

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Contribution of serotonergic and nitrergic pathways, as well as monoamine oxidase-a and Na+, K+-ATPase enzymes in antidepressant-like action of ((4-tert-butylcyclohexylidene) methyl) (4-methoxystyryl) sulfide (BMMS)

Autor: Cristiane Luchese, Marina Laura C.P. Torres, Renata L. de Oliveira, Marina C. Dilelio, Jaini J. Paltian, Mikaela P. Pinz, Michele P Moreira, Guilherme T. Voss, Claudio C. Silveira, Ethel A. Wilhelm

Publikováno v: Metabolic Brain Disease. 34:1313-1324

The present study investigated a possible antidepressant-like effect of ((4-tert-butylcyclohexylidene)methyl) (4-methoxystyryl) sulfide (BMMS) by using the forced swimming test (FST) and the tail suspension test (TST) in Swiss mice. The contribution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d01fbea2880d80e5eea7ad26ad46bd04
https://doi.org/10.1007/s11011-019-00436-x

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Polysaccharide-based film loaded with vitamin C and propolis: A promising device to accelerate diabetic wound healing

Autor: Rodrigo de Almeida Vaucher, Ane G. Vogt, Joanna V.Z. Echenique, Matheus S. Gularte, Ethel A. Wilhelm, Janice Luehring Giongo, André R. Fajardo, Cristiane Luchese, Guilherme T. Voss, Mauro P. Soares

Publikováno v: International Journal of Pharmaceutics. 552:340-351

Wound healing can be a painful and time-consuming process in patients with diabetes mellitus. In light of this, the use of wound healing devices could help to accelerate this process. Here, cellulose-based films loaded with vitamin C (VitC) and/or pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432657839e0fb673df14292ee65e3172
https://doi.org/10.1016/j.ijpharm.2018.10.009

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Topic application of meloxicam-loaded polymeric nanocapsules as a technological alternative for treatment of the atopic dermatitis in mice

Autor: Ethel A. Wilhelm, Renata L. de Oliveira, Karline da Costa Rodrigues, Jaini J. Paltian, Cristiane Luchese, Caren A.R. da Fonseca, Guilherme T. Voss, Rodrigo de Almeida Vaucher, Douglas Mroginski Weber, Francine R. Ianiski

Publikováno v: Journal of Applied Biomedicine. 16:337-343

This study investigated the effect of the topical treatment with meloxicam-loaded nanocapsules (M-NC) on symptoms, inflammatory response and oxidative parameters in an atopic dermatitis (AD) model in BALB/c mice. 2,4-Dinitrochlorobenzene (DNCB) was a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::933031eb52e0bc25c36d4bb094562c33
https://doi.org/10.1016/j.jab.2018.03.003

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Therapeutic and technological potential of 7-chloro-4-phenylselanyl quinoline for the treatment of atopic dermatitis-like skin lesions in mice

Autor: Ethel A. Wilhelm, Diego Alves, André R. Fajardo, Guilherme T. Voss, Jaqueline F. de Souza, Renata L. de Oliveira, Cristiane Luchese, Luis Fernando B. Duarte

Publikováno v: Materials Science and Engineering: C. 84:90-98

This study investigated the main effects of the oral treatment with 7-chloro-4-phenylselanyl quinoline (4-PSQ) on symptoms, inflammatory and oxidative parameters in an atopic dermatitis (AD) model in BALB/c mice. In addition, the possibility of antio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66502a4d2030e431e5da9f470007dcff
https://doi.org/10.1016/j.msec.2017.11.026

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Organoselenium compounds from purines: Synthesis of 6-arylselanylpurines with antioxidant and anticholinesterase activities and memory improvement effect

Autor: Renata L. de Oliveira, Gelson Perin, Ethel A. Wilhelm, Guilherme T. Voss, Benhur Godoi, Luis Fernando B. Duarte, Ricardo F. Schumacher, Cristiane Luchese, Diego Alves, Karline da Costa Rodrigues

Publikováno v: Bioorganic & Medicinal Chemistry. 25:6718-6723

We describe here a simple method for the synthesis of 6-arylselanylpurines with antioxidant and anticholinesterase activities, and memory improvement effect. This class of compounds was synthesized in good yields by a reaction of 6-chloropurine with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c5fc16c164fe188e233657215dcf39
https://doi.org/10.1016/j.bmc.2017.11.019

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Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators

Autor: Renata L. de Oliveira, Cristiane Luchese, Carl H. Schiesser, Vinicius Farias Campos, Michael J. Davies, Mauro P. Soares, Ethel A. Wilhelm, Guilherme T. Voss, William Borges Domingues

Publikováno v: Journal of Trace Elements in Medicine and Biology. 67:126795

Background Atopic dermatitis (AD) is a multifactorial chronic inflammatory disease that affects ∼20 % of children and 3% of adults globally and is generally treated by the topical application of steroidal drugs that have undesirable side-effects. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7c85e83dff95c7e40aa028728e3c48
https://doi.org/10.1016/j.jtemb.2021.126795

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7-Chloro-4-phenylsulfonyl quinoline, a new antinociceptive and anti-inflammatory molecule: Structural improvement of a quinoline derivate with pharmacological activity

Autor: Manoela do Sacramento, Ethel A. Wilhelm, Mikaela P. Pinz, Angélica S. Reis, Diego Alves, Renata L. de Oliveira, Juliano A. Roehrs, Cristiane Luchese, Guilherme T. Voss, Ane G. Vogt

Publikováno v: Regulatory Toxicology and Pharmacology. 90:72-77

The present study was designed to examine the antinociceptive and anti-inflammatory effects of 7-chloro-4-phenylsulfonyl quinoline (PSOQ). Mice were orally (p.o) pretreated with PSOQ (0.01–10 mg/kg), meloxicam (10 mg/kg), 30 min prior to the acetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a990c15c903f0b00739a04838388ee1e
https://doi.org/10.1016/j.yrtph.2017.08.014

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