Oxygen therapy alternatives in COVID-19: From classical to nanomedicine

Autor: Luis F.T. Pereira, Camila A. Dallagnol, Tassiana H. Moulepes, Clara Y. Hirota, Pedro Kutsmi, Lucas V. dos Santos, Cleverton L. Pirich, Guilherme F. Picheth

Publikováno v: Heliyon, Vol 9, Iss 4, Pp e15500- (2023)

Around 10–15% of COVID-19 patients affected by the Delta and the Omicron variants exhibit acute respiratory insufficiency and require intensive care unit admission to receive advanced respiratory support. However, the current ventilation methods di

Externí odkaz: https://doaj.org/article/8ce17fbecd4e47b2b8e778771a7eda0c

Ligand-mediated nanomedicines against breast cancer: a review

Autor: Guilherme F Picheth, Fernando A de O Ganzella, João OC Filizzola, Yan K Canquerino, Gabriela C Cardoso, Michelle B Collini, Leonardo B Colauto, Maria Cristina Figueroa-Magalhães, Edneia ASR Cavalieri, Giseli Klassen

Publikováno v: Nanomedicine. 17:645-664

Ligand-mediated targeting represents the cutting edge in precision-guided therapy for several diseases. Surface engineering of nanomedicines with ligands exhibiting selective or tailored affinity for overexpressed biomolecules of a specific disease m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b95ebc3d6b73433ba673f018162372
https://doi.org/10.2217/nnm-2021-0473

Wound healing action of nitric oxide‐releasing self‐expandable collagen sponge

Autor: Carlos Poblete Jara, Marcelo Ganzarolli de Oliveira, Valeria Póvoa, Guilherme F. Picheth, Laura C. E. da Silva, Eliana P. Araújo, Giovanna Paccillo dos Santos

Publikováno v: Journal of Tissue Engineering and Regenerative Medicine. 14:807-818

Mounting evidence showing that local nitric oxide (NO) delivery may significantly improve the wound healing process has stimulated the development of wound dressings capable of releasing NO topically. Herein, we describe the preparation of a self-exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea826cf54cc0186dd67dc3ae46a83cc0
https://doi.org/10.1002/term.3046

S-nitrosothiol-terminated poly(vinyl alcohol): Nitric oxide release and skin blood flow response

Autor: Alexander N. Zelikin, Marcelo Ganzarolli de Oliveira, Leonardo P. Giglio, Kaja Borup Løvschall, Guilherme F. Picheth

Publikováno v: Giglio, L P, Picheth, G F, Løvschall, K B, Zelikin, A N & de Oliveira, M G 2020, ' S-nitrosothiol-terminated poly(vinyl alcohol) : Nitric oxide release and skin blood flow response ', Nitric Oxide-Biology and Chemistry, vol. 98, pp. 41-49 . https://doi.org/10.1016/j.niox.2020.03.002

Polymeric biomaterials capable of delivering nitric oxide (NO) topically can be used to enhance skin blood flow (SkBF) and accelerate wound healing. Herein, we used reversible addition-fragmentation chain transfer radical (RAFT) polymerization to syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c501e17fda64dfa976858ff5870b8426
https://pubmed.ncbi.nlm.nih.gov/32147583

Nitric oxide releasing collagen membranes for the topical treatment of wounds

Autor: Marcelo Ganzarolli de Oliveira, Guilherme F. Picheth, Valéria Cristina Oliveira Póvoa, Eliana P. Araújo, Giovanna Paccillo dos Santos

Publikováno v: Revista dos Trabalhos de Iniciação Científica da UNICAMP.

Nitric oxide (NO) donor biomaterials have great potential to promote tissue regeneration and healing. Among the materials that can be used for this purpose, collagen has high biocompatibility, low antigenic activity and is already used commercially i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c21ca62e5ecf256a28e54abbf3832fa
https://doi.org/10.20396/revpibic262018537