Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Guilhem Clary"'
Autor:
Marie-Lise Lacombe, Frederic Lamarche, Olivier De Wever, Teresita Padilla-Benavides, Alyssa Carlson, Imran Khan, Anda Huna, Sophie Vacher, Claire Calmel, Céline Desbourdes, Cécile Cottet-Rousselle, Isabelle Hininger-Favier, Stéphane Attia, Béatrice Nawrocki-Raby, Joël Raingeaud, Christelle Machon, Jérôme Guitton, Morgane Le Gall, Guilhem Clary, Cedric Broussard, Philippe Chafey, Patrice Thérond, David Bernard, Eric Fontaine, Malgorzata Tokarska-Schlattner, Patricia Steeg, Ivan Bièche, Uwe Schlattner, Mathieu Boissan
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-29 (2021)
Abstract Background Mitochondrial nucleoside diphosphate kinase (NDPK-D, NME4, NM23-H4) is a multifunctional enzyme mainly localized in the intermembrane space, bound to the inner membrane. Results We constructed loss-of-function mutants of NDPK-D, l
Externí odkaz:
https://doaj.org/article/64c3e3bcb5024675ac11f551606b20d8
Autor:
David Bernard, Malgorzata Tokarska-Schlattner, Anda Huna, Patrice Thérond, Isabelle Hininger-Favier, Sophie Vacher, Patricia S. Steeg, Céline Desbourdes, Guilhem Clary, Philippe Chafey, Morgane Le Gall, Imran Khan, Jérôme Guitton, Olivier De Wever, Christelle Machon, Alyssa Carlson, Ivan Bièche, Teresita Padilla-Benavides, Cécile Cottet-Rousselle, Uwe Schlattner, Stéphane Attia, Béatrice Nawrocki-Raby, Cédric Broussard, Frédéric Lamarche, Mathieu Boissan, Joël Raingeaud, Marie-Lise Lacombe, Claire Calmel, Eric Fontaine
Publikováno v:
BMC BIOLOGY
BMC Biology
BMC Biology, BioMed Central, 2021, 19 (1), ⟨10.1186/s12915-021-01155-5⟩
BMC Biology, 2021, 19 (1), ⟨10.1186/s12915-021-01155-5⟩
BMC Biology, Vol 19, Iss 1, Pp 1-29 (2021)
BMC Biology
BMC Biology, BioMed Central, 2021, 19 (1), ⟨10.1186/s12915-021-01155-5⟩
BMC Biology, 2021, 19 (1), ⟨10.1186/s12915-021-01155-5⟩
BMC Biology, Vol 19, Iss 1, Pp 1-29 (2021)
Background Mitochondrial nucleoside diphosphate kinase (NDPK-D, NME4, NM23-H4) is a multifunctional enzyme mainly localized in the intermembrane space, bound to the inner membrane. Results We constructed loss-of-function mutants of NDPK-D, lacking ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbd007d0c6d8a5153e3d323369cab8a
https://hdl.handle.net/1854/LU-8738468
https://hdl.handle.net/1854/LU-8738468
Autor:
Meng-Er Huang, Guilhem Clary, Sabrina Batonnet-Pichon, Florence Delort, Fany Bourgois-Rocha, Eva Cabet, Onnik Agbulut, Alain Lilienbaum, Coralie Hakibilen, Patrick Vicart, Bertrand-David Segard
Publikováno v:
Experimental Cell Research
Experimental Cell Research, Elsevier, 2019, 383 (2), pp.111539. ⟨10.1016/j.yexcr.2019.111539⟩
Experimental Cell Research, Elsevier, 2019, 383 (2), pp.111539. ⟨10.1016/j.yexcr.2019.111539⟩
International audience; Desminopathies are a type of myofibrillar myopathy resulting from mutations in DES, encoding the intermediate filament protein desmin. They display heterogeneous phenotypes, suggesting environment influences. Patient muscle pr
Autor:
François Labrousse, Chabha Khifer, Antoine P. Brézin, Alexis Régent, Kim Heang Ly, Christian Federici, Véronique Baud, Guilhem Clary, Sébastien Lofek, Véronique Witko-Sarsat, Elisabeth Vidal, Luc Mouthon, Claire Le Jeunne, Laura Mesturoux, Loïc Guillevin, Matthieu Groh, Philippe Chafey, Cédric Broussard
Publikováno v:
Autoimmunity reviews. 16(4)
Objective The pathophysiology of giant cell arteritis (GCA) and the mechanisms underlying vascular remodeling, are poorly understood. We aimed to compare vascular smooth muscle cells (VSMCs) from patients with GCA and controls by a proteomic and gene
Autor:
M. Le Gall, Sébastien Lofek, L. Mouthon, Christopher P. Denton, Benjamin Chaigne, T. Krieg, N. Dumoitier, Pia Moinzadeh, Philippe Chafey, Guilhem Clary
Publikováno v:
La Revue de Médecine Interne. 38:A52-A53
Introduction La sclerodermie systemique (ScS) est une maladie auto-immune rare caracterisee par une auto-immunite, une vasculopathie et de la fibrose. La fibrose est due a une activation exageree des fibroblastes par le facteur de croissance TGF-β.
Publikováno v:
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, 1860 (1 Pt A), pp.8-19. 〈10.1016/j.bbagen.2015.10.007〉
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, 1860 (1 Pt A), pp.8-19. ⟨10.1016/j.bbagen.2015.10.007⟩
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, 1860 (1 Pt A), pp.8-19. 〈10.1016/j.bbagen.2015.10.007〉
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, 1860 (1 Pt A), pp.8-19. ⟨10.1016/j.bbagen.2015.10.007⟩
Background α-Synuclein (α-Syn) fibrils are the main constituent of Lewy bodies and a neuropathological hallmark of Parkinson's disease (PD). The propagation of α-Syn assemblies from cell to cell suggests that they are involved in PD progression. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433f5e46a01b3a7e87d78934122b3c30
https://hal.archives-ouvertes.fr/hal-01240193
https://hal.archives-ouvertes.fr/hal-01240193
Autor:
Jean-Daniel Chiche, Frédéric Pène, Anne-Lise Rossi, David Grimaldi, Philippe Chafey, Nadia Belaïdouni, Guilhem Clary, Emilie Courtine, Yann-Erick Claessens, Julie Toubiana, Jean-Paul Mira
Publikováno v:
Journal of Biological Chemistry. 286:23319-23333
Toll-like receptor 2 (TLR2) plays an essential role in innate immunity by the recognition of a large variety of pathogen-associated molecular patterns. It induces its recruitment to lipid rafts induces the formation of a membranous activation cluster
Autor:
Claire Fernandez, Sébastien Lofek, N. Dumoitier, Pia Moinzadeh, Thomas Krieg, Philippe Chafey, Luc Mouthon, Christopher P. Denton, Guilhem Clary, Morgane Le Gall, Benjamin Chaigne
Publikováno v:
PROTEOMICS – Clinical Applications. 13:1800069
Purpose Systemic sclerosis (SSc) is characterized by autoimmunity, vasculopathy and fibrosis. Fibrosis is due to an activation of fibroblasts by the transforming growth factor-s (TGF-s). This study investigates the proteomic response of SSc fibroblas
Autor:
Christian Federici, Corinne Bardot, Isabelle Batisson, Pascale Besse-Hoggan, Cédric Broussard, Louis Carles, Philippe Chafey, Guilhem Clary, Morgane Le Gall
Publikováno v:
Environmental Pollution (1970)
Environmental Pollution (1970), Elsevier Science, 2015, 199, pp.198-208. 〈10.1016/j.envpol.2015.01.029〉
Environmental Pollution (1970), Elsevier Science, 2015, 199, pp.198-208. ⟨10.1016/j.envpol.2015.01.029⟩
Environmental Pollution (1970), 2015, 199, pp.198-208. ⟨10.1016/j.envpol.2015.01.029⟩
Environmental Pollution (1970), Elsevier Science, 2015, 199, pp.198-208. 〈10.1016/j.envpol.2015.01.029〉
Environmental Pollution (1970), Elsevier Science, 2015, 199, pp.198-208. ⟨10.1016/j.envpol.2015.01.029⟩
Environmental Pollution (1970), 2015, 199, pp.198-208. ⟨10.1016/j.envpol.2015.01.029⟩
International audience; Toxicity of pesticides towards microorganisms can have a major impact on ecosystem function. Nevertheless, some microorganisms are able to respond quickly to this stress by degrading these molecules. The edaphic Bacillus megat
Autor:
Guillonneau François, Patricia Rouet-Benzineb, Guilhem Clary, Jean-Jacques Mercadier, Miresta Prévilon, Christian Federeci, Morgane Le Gall, Cédric Broussard, Philippe Chafey, Mylène Pezet
Publikováno v:
Physiological Reports
Chronic pressure overload (PO) induces pathological left ventricular hypertrophy (LVH) leading to congestive heart failure (HF). Overexpression of FKBP12.6 (FK506-binding protein [K]) in mice should prevent Ca2+-leak during diastole and may improve o