Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Guijun Zhao"'
Autor:
Zhongxian Xu, Yinglian Chen, Dejun Zeng, Xin Shi, Tingting Zheng, Chenglu Zhang, Xiaolan Feng, Linbo Yan, Guijun Zhao, Hang Jie
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Musk, secreted by adult male forest musk deer, is a kind of precious Chinese traditional medicine for treating cardiovascular, cerebrovascular and neurogenic diseases. However, a lack of knowledge on musk biosynthetic mechanism and limited m
Externí odkaz:
https://doaj.org/article/7614b2c4a4954280908582f8c154b358
Autor:
Zhongxian Xu, Feng Li, Qian Liu, Tianyuan Ma, Xiaolan Feng, Guijun Zhao, Dejun Zeng, Diyan Li, Hang Jie
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Forest musk deer is the most important animal for natural musk production, and the musk composition changes periodically during musk secretion, accompanied by variation in the com-position of deer-symbiotic bacteria. GC-MS and 16S rRNA sequencing wer
Externí odkaz:
https://doaj.org/article/1b75168d80e34b54a450614379788563
Autor:
Yuan Yang, Hongmin Ge, Xijin Wang, Xuejun Liu, Keqing Li, Gang Wang, Xiaodong Yang, Huaili Deng, Meijuan Sun, Ruiling Zhang, Jindong Chen, Duanfang Cai, Hong Sang, Xianglai Liu, Guilai Zhan, Guijun Zhao, Haiyun Li, Zhiyuan Xun
Publikováno v:
Annals of General Psychiatry, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background Blonanserin (BNS) had been undergoing post-market surveillance (PMS) since September 2018. Using the surveillance data, we did this analysis to assess the safety and effectiveness of different doses of BNS to explore a sufficient
Externí odkaz:
https://doaj.org/article/d649eb5ed11c495fb0e922503d24aa38
Autor:
Qijing Bo, Xijin Wang, Xuejun Liu, Hong Sang, Zhiyuan Xun, Ruiling Zhang, Xiaodong Yang, Huaili Deng, Keqing Li, Jindong Chen, Meijuan Sun, Guijun Zhao, Xianglai Liu, Duanfang Cai, Guilai Zhan, Juhong Li, Haiyun Li, Gang Wang
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background A post-marketing surveillance of blonanserin has been ongoing since September 2018. The aim of this study was to assess the effectiveness and safety of oral blonanserin in Chinese young and middle-aged female patients with schizop
Externí odkaz:
https://doaj.org/article/a83bc3dda3b142aea5978dbccef6f415
Autor:
Haishan Wu, Xijin Wang, Xuejun Liu, Hong Sang, Qijing Bo, Xiaodong Yang, Zhiyuan Xun, Keqing Li, Ruiling Zhang, Meijuan Sun, Duanfang Cai, Huaili Deng, Guijun Zhao, Juhong Li, Xianglai Liu, Guilai Zhan, Jindong Chen
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Schizophrenia is an unexplained, complex and serious mental illness. Blonanserin (BNS) is a new antipsychotic drug widely used in the treatment of schizophrenia. However, large-scale clinical studies have not been conducted in China. A multi-center,
Externí odkaz:
https://doaj.org/article/95ba63d4a1844d41903d6dc88e125b6a
Autor:
Xin Shi, Dejun Zeng, Guijun Zhao, Chenglu Zhang, Xiaolan Feng, Chengli Zheng, Diyan Li, Ming Zhang, Hang Jie
Publikováno v:
Animals, Vol 13, Iss 10, p 1678 (2023)
Muskrat musk is considered to be a potential substitute for traditional musk. However, little is known about the similarity between muskrat musk and musk, and whether it is related to muskrat age. In this study, muskrat musk (MR1, MR2, and MR3) were
Externí odkaz:
https://doaj.org/article/36f659a8cad9413bbb5484259e89ec44
Autor:
Xiao Wang, Mengke Chen, Xiong Liang, Yu Bai, Judeng Zeng, Xiaoyi Xu, Hao Li, Jing Wang, Keyu Fan, Guijun Zhao
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
RING finger protein 135 has an important role in the occurrence of many cancers; however its regulation and function of RNF135 in hepatocellular carcinoma remains unknown. The promoter methylation status and mRNA expression of RNF135 was evaluated by
Externí odkaz:
https://doaj.org/article/447278e35fc6463f9c3206f7e6dd57c4
Publikováno v:
PeerJ, Vol 9, p e12710 (2021)
Background The formation of musk is a complex biophysical and biochemical process that change with the rut of male forest musk deer. We have reported that the mating status of male forest musk deer might result to the variations of chemical compositi
Externí odkaz:
https://doaj.org/article/2a86c7604b674315ba74292ff6708a82
Correction of RNA splicing defect in β654-thalassemia mice using CRISPR/Cas9 gene-editing technology
Autor:
Dan Lu, Xiuli Gong, Yudan Fang, Xinbing Guo, Yanwen Chen, Fan Yang, Guijun Zhao, Qingwen Ma, Yitao Zeng, Fanyi Zeng
Publikováno v:
Haematologica, Vol 107, Iss 6 (2021)
β654-thalassemia is a prominent Chinese subtype of b-thalassemia, representing 17% of all cases of β-thalassemia in China. The molecular mechanism underlying this subtype involves the IVS-2-654 C→T mutation leading to aberrant β-globin RNA splic
Externí odkaz:
https://doaj.org/article/1401a5e3fe9940a791565863a9f305fe
Publikováno v:
2022 3rd China International SAR Symposium (CISS).