Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Guihua Duan"'
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Drug repositioning is considered a promising drug development strategy with the goal of discovering new uses for existing drugs. Compared with the experimental screening for drug discovery, computational drug repositioning offers lower co
Externí odkaz:
https://doaj.org/article/44d26788322941b48be941546f7b35d6
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Increasing evidence has proved that miRNA plays a significant role in biological progress. In order to understand the etiology and mechanisms of various diseases, it is necessary to identify the essential miRNAs. However, it is time-consuming and exp
Externí odkaz:
https://doaj.org/article/583535f999fa429ca99734621765ba4b
Autor:
Wenjing Zhang, Haitao Yang, Zhongqiu Wang, Yanting Wu, Jingzhai Wang, Guihua Duan, Qiang Guo, Yu Zhang
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Transcription factors (TFs) may be engaged in reciprocal regulatory circuits with certain miRNAs to maintain cellular homeostasis. Disequilibrium of the reciprocities by certain tumor-related stimuli may give rise to deregulation
Externí odkaz:
https://doaj.org/article/fb17e195bb124343842a5fd5de00c39d
Publikováno v:
BMC Plant Biology, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Some of the pathogenic effector proteins play an active role in stimulating the plant defense system to strengthen plant resistance. Results In this study, ultra-high performance liquid chromatography-quadrupole time-of-flight mas
Externí odkaz:
https://doaj.org/article/ef45f7ac18d04298b0ff939c72977c8c
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background MicroRNAs (miRNAs) are a kind of small noncoding RNA molecules that are direct posttranscriptional regulations of mRNA targets. Studies have indicated that miRNAs play key roles in complex diseases by taking part in many biologica
Externí odkaz:
https://doaj.org/article/844374cdcdf140809df453470a38dd29
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S23, Pp 1-9 (2019)
Abstract Background Viral infectious diseases are the serious threat for human health. The receptor-binding is the first step for the viral infection of hosts. To more effectively treat human viral infectious diseases, the hidden virus-receptor inter
Externí odkaz:
https://doaj.org/article/b1dd3ca365414767ac9819f286db7fb8
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S15, Pp 1-10 (2019)
Abstract Background A drug-drug interaction (DDI) is defined as a drug effect modified by another drug, which is very common in treating complex diseases such as cancer. Many studies have evidenced that some DDIs could be an increase or a decrease of
Externí odkaz:
https://doaj.org/article/497af112c620414ab07e5f1c041b8c7f
Publikováno v:
Materials, Vol 15, Iss 17, p 6081 (2022)
The behavior and the mechanism of fatigue crack propagation in CrCoNi medium-entropy alloys (MEAs) with heterogeneous microstructures were investigated in this paper. After cold-rolling and recrystallization annealing at different temperatures and ti
Externí odkaz:
https://doaj.org/article/e93ab737e24f41749bbe3b70a4b6e32c
Autor:
Jinying Dai, Bin Wang, Jinfang Sheng, Zejun Sun, Faiza Riaz Khawaja, Aman Ullah, Dawit Aklilu Dejene, Guihua Duan
Publikováno v:
IEEE Access, Vol 7, Pp 131719-131731 (2019)
The identification of influential nodes in complex networks has been widely used to suppress rumor dissemination and control the spread of epidemics and diseases. However, achieving high accuracy and comprehensiveness in node influence ranking is tim
Externí odkaz:
https://doaj.org/article/2f14f1a503cb45a59a5bfd10c3ee3912
Publikováno v:
Materials, Vol 15, Iss 14, p 4756 (2022)
The fracture behavior of the Cu/Sn-3.0Ag-0.5Sn (SAC305)/Cu solder joint was investigated by conducting tensile tests with in situ X-ray micro-computed tomography (μ-CT) observation, and finite element (FE) simulation. The tensile fracture process of
Externí odkaz:
https://doaj.org/article/568660bdd76645e2aa24b9ddec27f7b0