Výsledky vyhledávání - "Guihong D Qi"

Akademický článek

Quantitative phosphoproteomic analysis identifies novel functional pathways of tumor suppressor DLC1 in estrogen receptor positive breast cancer.

Autor: Yesim Gökmen-Polar, Jason D True, Edyta Vieth, Yuan Gu, Xiaoping Gu, Guihong D Qi, Amber L Mosley, Sunil S Badve

Publikováno v: PLoS ONE, Vol 13, Iss 10, p e0204658 (2018)

Deleted in Liver Cancer-1 (DLC1), a member of the RhoGAP family of proteins, functions as a tumor suppressor in several cancers including breast cancer. However, its clinical relevance is unclear in breast cancer. In this study, expression of DLC1 wa

Externí odkaz: https://doaj.org/article/cd563584e9fc4422a41fbd701a8a070e

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Mutant thermal proteome profiling for characterization of missense protein variants and their associated phenotypes within the proteome

Autor: Aruna B. Wijeratne, Amber L. Mosley, Edward Simpson, Jonah Z. Vilseck, Jose F. Victorino, H. R. Sagara Wijeratne, Guihong D. Qi, Sarah A. Peck Justice, Monica P. Barron

Publikováno v: J Biol Chem

Temperature-sensitive (TS) missense mutants have been foundational for characterization of essential gene function. However, an unbiased approach for analysis of biochemical and biophysical changes in TS missense mutants within the context of their f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5ec9c9135de9f846ed7af6a48fc4be
https://pubmed.ncbi.nlm.nih.gov/32878984

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Quantitative phosphoproteomic analysis identifies novel functional pathways of tumor suppressor DLC1 in estrogen receptor positive breast cancer

Autor: Yuan Gu, Jason D. True, Guihong D. Qi, Edyta Vieth, Yesim Gökmen-Polar, Sunil Badve, Xiaoping Gu, Amber L. Mosley

Publikováno v: PLoS ONE, Vol 13, Iss 10, p e0204658 (2018)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c218df1aeb537c598c431ca32bd3b129
https://doi.org/10.1371/journal.pone.0204658

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Abstract 2695: Quantitative phosphoproteome analysis identifies novel functional pathways of tumor suppressor DLC1 in estrogen receptor-positive breast cancer

Autor: Jason D. True, Amber L. Mosley, Guihong D. Qi, Edyta Vieth, Xiaoping Gu, Yuan Gu, Sunil Badve, Yesim Gökmen-Polar

Publikováno v: Cancer Research. 78:2695-2695

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09e0e531af4057369894176eacba1e12
https://doi.org/10.1158/1538-7445.am2018-2695

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Phosphopeptide mapping of DLC1 in ER+ breast cancer reveals AMOTL2, a key hippo pathway component, as an important target

Autor: Jason D True, Edyta Vieth, Yesim Gökmen-Polar, Guihong D Qi, Amber L. Mosley, Sunil Badve

Publikováno v: Journal of Clinical Oncology. 35:11592-11592

11592 Background: Metastases suppressor genes are believed to control tumor progression and metastases. Deleted in Liver Cancer 1 (DLC1) acts as a gatekeeper for tumor and metastasis suppression. Low expression of DLC1 correlates with poor prognosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4732383f5cb0fa2d90491b9c5b1c5085
https://doi.org/10.1200/jco.2017.35.15_suppl.11592

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