Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Guigao Lin"'
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111177- (2024)
Summary: Fecal DNA-based Syndecan 2 (SDC2) methylation detection is a promising non-invasive strategy for early colorectal cancer (CRC) screening. In China, commercial assays for SDC2 methylation detection vary in sensitivity and specificity, yet the
Externí odkaz:
https://doaj.org/article/954f702fffb949929ac388bb7b2cfbc5
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Chlamydia trachomatis (CT) is a significant sexually transmitted pathogen known to evoke severe complications, including infertility. Nucleic acid amplification tests (NAATs) are recommended by the World Health Organization to detect CT infe
Externí odkaz:
https://doaj.org/article/e0f33d20baa84ce1a153edc23e5270a6
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
As a biomarker that affects treatment decisions of immune checkpoint inhibitors, the accuracy, reliability, and comparability of tumor mutational burden (TMB) estimation is of paramount importance. To improve the consistency and reliability of these
Externí odkaz:
https://doaj.org/article/52994b86693c489fadc767edc12bef79
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
This study aimed to evaluate inter-laboratory classification concordance for copy number variants (CNVs) with a semiquantitative point-based scoring metric recommended by the American College of Medical Genetics and Genomics (ACMG) and Clinical Genom
Externí odkaz:
https://doaj.org/article/3c2a2eeaab0944e684953eb82dd14da3
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Exome sequencing has become an effective diagnostic method for Mendelian disorders. But the quality of services differs widely across laboratories in China, particularly in variant classification, even with the adoption of the ACMG guidelines. As an
Externí odkaz:
https://doaj.org/article/db9d7834ed0f46269db1c780d00147ad
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-6 (2017)
Abstract Background The early detection of type 1 diabetes (T1D) largely depends on a reliable approach to monitor β cell loss. An effective way to evaluate the decline of β cell mass would allow early preventative intervention to preserve insulin
Externí odkaz:
https://doaj.org/article/2c81e90b07ab484a990d6c87a427d26b
Autor:
Lang Yi, Mingju Hao, Tian Lu, Guigao Lin, Lida Chen, Ming Gao, Gaowei Fan, Dong Zhang, Guojing Wang, Xin Yang, Yulong Li, Kuo Zhang, Rui Zhang, Yanxi Han, Lunan Wang, Jinming Li
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
The κ/λ hybrid antibodies in normal human serum were reported recently, but their clinical relevance has not yet been explored. Rheumatoid arthritis (RA) is one of the major joint diseases, and the early diagnosis and treatment of RA remain a chall
Externí odkaz:
https://doaj.org/article/14c08e98b95241309933658ecf6874d4
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0148081 (2016)
Irinotecan is widely used in the treatment of solid tumors, especially in colorectal cancer and lung cancer. Molecular testing for UGT1A1 genotyping is increasingly required in China for optimum irinotecan administration. In order to determine the pe
Externí odkaz:
https://doaj.org/article/aff1735b15a14602b4df57a4e8c4f1ef
Autor:
Guojing Wang, Yu Sun, Kuo Zhang, Tingting Jia, Mingju Hao, Dong Zhang, Le Chang, Lei Zhang, Rui Zhang, Guigao Lin, Rongxue Peng, Jinming Li
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151695 (2016)
Externí odkaz:
https://doaj.org/article/9227535a009e44379d019f6feac94335
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162361 (2016)
Tamoxifen has been successfully used for treating breast cancer and preventing cancer recurrence. Cytochrome P450 2D6 (CYP2D6) plays a key role in the process of metabolizing tamoxifen to its active moiety, endoxifen. Patients with variants of the CY
Externí odkaz:
https://doaj.org/article/367a031ef4014e90af35963c79494a3b