Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Guifeng Hao"'
Autor:
FengQi Zhang, YiYang Zhang, JiaWang Zhou, Ying Cai, ZhiYu Li, Jing Sun, ZhiJun Xie, GuiFeng Hao
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Rheumatoid arthritis, a chronic autoimmune disease, is characterized by synovial hyperplasia and cartilage erosion. Here, we investigated the potential mechanism of action of quercetin, the main component of flavonoids, in treatin
Externí odkaz:
https://doaj.org/article/1b92413d0cd5404dab95e3b429f6da09
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Gut microbiota plays a significant role in the development and treatment of gouty arthritis. Simiao decoction has been shown to alleviate gouty arthritis by inhibiting inflammation, regulating NLRP3 inflammasome, and altering gut
Externí odkaz:
https://doaj.org/article/9c63bc666a5143d59991a9db4ec80b94
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Growing evidence has suggested that gut microbiota is closely related to the risk of irritable bowel syndrome (IBS), but whether there is a causal effect remains unknown. We adopted a Mendelian randomization (MR) approach to evalu
Externí odkaz:
https://doaj.org/article/906115688ea447109e65241f6bac9703
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Renal injury is one of the most common clinical manifestations of patients with hyperuricaemia/gout. The precise pathophysiological mechanism(s) for the renal injury is still unknown. Furthermore, it is also unclear whether the clinical therapies (e.
Externí odkaz:
https://doaj.org/article/a6e1c89f493547b3a993771731048a38
Autor:
Jiajia Wang, Jiaying Wang, Wenxiang Hong, Lulu Zhang, Liqian Song, Qi Shi, Yanfei Shao, Guifeng Hao, Chunyan Fang, Yueping Qiu, Lijun Yang, Zhaoxu Yang, Jincheng Wang, Ji Cao, Bo Yang, Qiaojun He, Qinjie Weng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Optineurin (OPTN) has been implicated in various biological processes, but its function in dendritic cells (DC) maturation is still unclear. Here the authors show, by characterizing Optn-conditional knockout mice, that the loss of OPTN induces Jak2/S
Externí odkaz:
https://doaj.org/article/ed01766df50a46f3ab6099205d41690e
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/561ba394a9074215bb184ce0f00734f4
Publikováno v:
The Journal of Organic Chemistry. 88:2433-2442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cceb0e97663edaea39cb8caffb6ea01
https://doi.org/10.1021/acs.joc.2c02858
https://doi.org/10.1021/acs.joc.2c02858
Autor:
Wenxiang Hong, Liqian Song, Jincheng Wang, Qi Shi, Lijun Yang, Qiaojun He, Jiajia Wang, Yanfei Shao, Bo Yang, Qinjie Weng, Lulu Zhang, Chunyan Fang, Ji Cao, Guifeng Hao, Zhaoxu Yang, Yueping Qiu, Jiaying Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Optineurin (OPTN) has important functions in diverse biological processes and diseases, but its effect on dendritic cell (DC) differentiation and functionality remains elusive. Here we show that OPTN is upregulated in human and mouse DC maturation, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c14d8a98ff9819363d86bb256a05e0
https://doaj.org/article/ed01766df50a46f3ab6099205d41690e
https://doaj.org/article/ed01766df50a46f3ab6099205d41690e
Publikováno v:
Organicbiomolecular chemistry. 20(21)
A metal-free three-component protocol for quinoline synthesis is developed by using alkyl lactates, anilines and α-keto acids. In vitro experiments disclose the attractive anti-inflammatory activity of these quinoline compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879ed5bcdb1d46bd8fbd4a7f57e9dc39
https://pubmed.ncbi.nlm.nih.gov/35579116
https://pubmed.ncbi.nlm.nih.gov/35579116
Publikováno v:
Tetrahedron Letters. 60:219-222
The three-component synthesis of structurally unsymmetrical pyridines with polysubstituted structure has been realized via the catalytic system consisting of CuI and KHSO4. The employment of two different enaminones is the main factor allowing the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::751521182afbd1572875834706eebb3b
https://doi.org/10.1016/j.tetlet.2018.12.015
https://doi.org/10.1016/j.tetlet.2018.12.015