MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma

Autor: Zhang, Shile ^{a, b, 1}, Wei, Jun S. ^{a, 1}, Li, Samuel Q. ^a, Badgett, Tom C. ^{a, c}, Song, Young K. ^a, Agarwal, Saurabh ^d, Coarfa, Cristian ^d, Tolman, Catherine ^a, Hurd, Laura ^a, Liao, Hongling ^a, He, Jianbin ^a, Wen, Xinyu ^a, Liu, Zhihui ^e, Thiele, Carol J. ^e, Westermann, Frank ^f, Asgharzadeh, Shahab ^{g, h, i}, Seeger, Robert C. ^{g, h, i}, Maris, John M. ^{j, k, l, m}, Guidry Auvil, Jamie M. ⁿ, Smith, Malcolm A. ^o, Kolaczyk, Eric D. ^{b, p}, Shohet, Jason ^d, Khan, Javed ^{a, *}

Publikováno v: In Cancer Letters 28 February 2016 371(2):214-224

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

Autor: Walz AL; Division of Hematology-Oncology and Transplantation, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University's Feinberg School of Medicine, Chicago, IL 60611, USA., Ooms A; Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, Rotterdam CA 3000, the Netherlands., Gadd S; Department of Pathology and Laboratory Medicine, Lurie Children's Hospital, Northwestern University's Feinberg School of Medicine and Robert H. Lurie Cancer Center, Chicago, IL 60611, USA., Gerhard DS; Office of Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA., Smith MA; Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD 20892, USA., Guidry Auvil JM, Meerzaman D; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, MD 20892, USA., Chen QR; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, MD 20892, USA., Hsu CH; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, MD 20892, USA., Yan C; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, MD 20892, USA., Nguyen C; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, MD 20892, USA., Hu Y; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, MD 20892, USA., Bowlby R; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Brooks D; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Ma Y; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Mungall AJ; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Moore RA; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Schein J; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Marra MA; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6H 3N1, Canada., Huff V; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Dome JS; Division of Pediatric Hematology/Oncology, Children's National Medical Center, Washington, DC 20010, USA., Chi YY; Department of Biostatistics, University of Florida, Gainesville, FL 32610, USA., Mullighan CG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Ma J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Wheeler DA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Hampton OA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Jafari N; Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA., Ross N; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, OH 43205, USA., Gastier-Foster JM; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, OH 43205, USA., Perlman EJ; Department of Pathology and Laboratory Medicine, Lurie Children's Hospital, Northwestern University's Feinberg School of Medicine and Robert H. Lurie Cancer Center, Chicago, IL 60611, USA. Electronic address: eperlman@luriechildrens.org.

Publikováno v: Cancer cell [Cancer Cell] 2015 Feb 09; Vol. 27 (2), pp. 286-97.