Development of a Gut-on-a-Chip Model for High Throughput Disease Modeling and Drug Discovery

Autor: Jan Stallen, Dorota Kurek, Richard A.J. Janssen, Kai S. Erdmann, Henriëtte L. Lanz, Arnaud Nicolas, Jos Joore, Yee Xiang Chang, Claudia Beaurivage, Edo D. Elstak, Sebastiaan Johannes Trietsch, Paul Vulto, Elena Naumovska, Guido van Moolenbroek, Heidi Wouters

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 22

A common bottleneck in any drug development process is finding sufficiently accurate models that capture key aspects of disease development and progression. Conventional drug screening models often rely on simple 2D culture systems that fail to recap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa65558b0a3505cf5b7058ca67af61d

Development of a Gut-On-A-Chip Model for High Throughput Disease Modeling and Drug Discovery.

Autor: Beaurivage, Claudia^1,2 (AUTHOR) claudia.beaurivage@glpg.com, Naumovska, Elena^2,3 (AUTHOR) a.nicolas@mimetas.com, Chang, Yee Xiang¹ (AUTHOR) y.x.chang@students.uu.nl, Elstak, Edo D.¹ (AUTHOR) edo.elstak@glpg.com, Nicolas, Arnaud³ (AUTHOR) g.t.van.moolenbroek@umail.leidenuniv.nl, Wouters, Heidi¹ (AUTHOR) Heidi.Wouters-EXT@glpg.com, van Moolenbroek, Guido³ (AUTHOR) h.lanz@mimetas.com, Lanz, Henriëtte L.³ (AUTHOR) s.trietsch@mimetas.com, Trietsch, Sebastiaan J.³ (AUTHOR) j.joore@mimetas.com, Joore, Jos³ (AUTHOR) p.vulto@mimetas.com, Vulto, Paul³ (AUTHOR), Janssen, Richard A.J.¹ (AUTHOR), Erdmann, Kai S.² (AUTHOR), Stallen, Jan¹ (AUTHOR) jan.stallen@crl.com, Kurek, Dorota³ (AUTHOR) jan.stallen@crl.com

Publikováno v: International Journal of Molecular Sciences. Nov2019, Vol. 20 Issue 22, p5661-5661. 1p.