Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Guido Straten"'
Autor:
Guido Straten, Christian Schmeer, Alexandra Kretz, Ellen Gerhardt, Sebastian Kügler, Jörg B. Schulz, Claude Gravel, Mathias Bähr, Stefan Isenmann
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 123-133 (2002)
Following transection of the optic nerve (ON) in the adult rat, retinal ganglion cells (RGCs) undergo degeneration, and within 14 days 85% of axotomized RGCs die by apoptosis. Adenoviral delivery of the mammalian caspase inhibitor X-chromosome-linked
Externí odkaz:
https://doaj.org/article/f54dbb76051244d1b560be297a2bf8da
Autor:
Konstantinos Stellos, Guido Straten, Nadine Hoffmann, Elke Stransky, Gerhard W. Eschweiler, Thomas Leyhe, Christoph Laske
Publikováno v:
The International Journal of Neuropsychopharmacology. 14:399-404
The neurotrophin brain-derived neurotrophic factor (BDNF) plays a critical role in neuronal survival, synaptic plasticity, and memory. Several recent studies have demonstrated altered BDNF serum levels in Alzheimer's disease (AD) patients. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfccdccdb1a153e9535c54f64a231253
https://doi.org/10.1017/s1461145710001008
https://doi.org/10.1017/s1461145710001008
Autor:
Konstantinos Stellos, Christos Gkotsis, Guido Straten, Meinrad Gawaz, Gerhard W. Eschweiler, Kateryna Sopova, Thomas Leyhe, Christoph Laske
Publikováno v:
Journal of Alzheimer's Disease. 21:1263-1269
Plasma levels of amyloid-β (Aβ) peptides are potential biomarkers of early cognitive impairment and of Alzheimer's disease (AD) risk. However, the association of Aβ peptides with the rate of cognitive decline in AD patients is still unclear. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995f0abb106a5205129922eca9e7996c
https://doi.org/10.3233/jad-2010-100510
https://doi.org/10.3233/jad-2010-100510
Autor:
Guido Straten, Thomas Leyhe, E. Stransky, N. Hoffmann, Walter Maetzler, Christoph Laske, G.W. Eschweiler
Publikováno v:
Current Alzheimer Research. 7:409-414
Macrophage colony-stimulating factor (M-CSF) is a hematopoietic growth factor that activates microglial cells, involved in phagocytosis of amyloid-beta (Abeta) in the brain. In the present study, we found in 50 patients with Alzheimer's disease (AD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec67a1822f3298be434f3c9d0337159
https://doi.org/10.2174/156720510791383813
https://doi.org/10.2174/156720510791383813
Autor:
Arno Hipp, Christoph Laske, Sabine Banschbach, Jürgen Machann, Gerhard W. Eschweiler, A. M. Niess, Sabine Bosch, Elke Stransky, Andreas Fritsche, Guido Straten
Publikováno v:
The International Journal of Neuropsychopharmacology. 13:595-602
Major depression (MD) has been associated with decreased brain-derived neurotrophic factor (BDNF) serum levels, while antidepressant drugs were found to increase these decreased BDNF levels. We investigated if this is also caused by a single exercise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecee3cf63cbe34c2ff829bbb7efa4d5e
https://doi.org/10.1017/s1461145709991234
https://doi.org/10.1017/s1461145709991234
Publikováno v:
Brain Research. 1090:1-14
The development of the retino-tectal projection as part of the central visual pathway is accomplished around postnatal day (P) 10-14 in rodents, and trophic factors are important for topographic refinement of this projection. Emerging data indicate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b79de3667689d333942e1c308f9e61
https://doi.org/10.1016/j.brainres.2006.01.131
https://doi.org/10.1016/j.brainres.2006.01.131
Autor:
Sebastian Kügler, Stefan Isenmann, Claude Gravel, Guido Straten, Mathias Bähr, Christian Schmeer
Publikováno v:
European Journal of Neuroscience. 15:637-643
Adult rat retinal ganglion cells undergo degeneration after optic nerve transection. Repeated intraocular injection of glial cell-line derived neurotrophic factor (GDNF) has been shown to be efficient in enhancing retinal ganglion cell survival follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::632dca6817be28025d0af2319c9aec4d
https://doi.org/10.1046/j.1460-9568.2002.01893.x
https://doi.org/10.1046/j.1460-9568.2002.01893.x
Autor:
Guido Straten, Anna-Maria Leiherr, Monika Milian, Thomas Leyhe, Stephan Müller, Gerhard W. Eschweiler
Publikováno v:
International psychogeriatrics. 25(1)
Background: The aim of this study was to assess the specificities of the Mini-Cog, the Clock Drawing Test (CDT), and the Mini-Mental State Examination (MMSE) against depression and healthy controls in a German Memory Clinic. Furthermore, we analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9992ebd74a0338158cd9f3975031ea2c
https://pubmed.ncbi.nlm.nih.gov/22906395
https://pubmed.ncbi.nlm.nih.gov/22906395
Autor:
Guido Straten, Gerhard W. Eschweiler, Stephan Müller, Thomas Leyhe, Anna-Maria Leiherr, Monika Milian
Publikováno v:
International psychogeriatrics. 24(5)
Background: The aim of this study was to compare the screening value of the Mini-Cog, Clock Drawing Test (CDT), Mini-Mental State Examination (MMSE) and the algorithm MMSE and/or CDT to separate elderly people with dementia from healthy depending on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e720e91277e55db6fcc62980664f6371
https://pubmed.ncbi.nlm.nih.gov/22172089
https://pubmed.ncbi.nlm.nih.gov/22172089
Autor:
Peter Annas, Christoph Laske, Guido Straten, Ralf Saur, Hans Basun, Thomas Leyhe, Thomas Gasser
Publikováno v:
Alzheimer's & Dementia. 7
study accounting for the treatment effect size observed in the GAP study. Conclusions: Early Phase 1 and 2 studies have demonstrated that human immunoglobulin may have potential in the treatment of mild to moderate AD. However, these preliminary find
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d57b223ef3ecfac3e6cdc7fe51a30244
https://doi.org/10.1016/j.jalz.2011.05.2251
https://doi.org/10.1016/j.jalz.2011.05.2251