Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Guido R M M Haenen"'
Autor:
Puji Astuti, Danielle M A Beurskens, Tanja Vajen, Gerry A F Nicolaes, Ming Zhang, Guido R M M Haenen
Publikováno v:
Makara Journal of Health Research, Vol 23, Iss 2, Pp 108-115 (2019)
Background: Neutrophil extracellular traps (NET) are extracellular fibers produced by activated neutrophils to kill bacteria. NET was recently found to be associated with several diseases, such as autoimmune diseases. NET formation, called NETosis, i
Externí odkaz:
https://doaj.org/article/9774940bb64c434f81995fb2b25f9960
Autor:
Marike W van Gisbergen, An M Voets, Rianne Biemans, Roland F Hoffmann, Marie-José Drittij-Reijnders, Guido R M M Haenen, Irene H Heijink, Kasper M A Rouschop, Ludwig J Dubois, Philippe Lambin
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182508 (2017)
Several clinically used drugs are mitotoxic causing mitochondrial DNA (mtDNA) variations, and thereby influence cancer treatment response. We hypothesized that radiation responsiveness will be enhanced in cellular models with decreased mtDNA content,
Externí odkaz:
https://doaj.org/article/462e516ed1d64c4bab3f328b4dc83585
Autor:
Simon J A van Kuijk, Roben G Gieling, Raymon Niemans, Natasja G Lieuwes, Rianne Biemans, Brian A Telfer, Guido R M M Haenen, Ala Yaromina, Philippe Lambin, Ludwig J Dubois, Kaye J Williams
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161040 (2016)
Carbonic anhydrase IX (CAIX) is a tumor-specific protein that is upregulated during hypoxic conditions where it is involved in maintaining the pH balance. CAIX causes extracellular acidification, thereby limiting the uptake of weak basic chemotherape
Externí odkaz:
https://doaj.org/article/ac88a352ecf64264b8874d1a5184899c
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92659 (2014)
Increasing evidence suggests a beneficial effect of lutein and zeaxanthin on the progression of age-related macular degeneration. The aim of this study was to investigate the effect of lutein or zeaxanthin enriched eggs or a lutein enriched egg-yolk
Externí odkaz:
https://doaj.org/article/b42cf9a7d4144059b3cbcaf6cdf44c00
Autor:
Dragan Milenkovic, Wim Vanden Berghe, Céline Boby, Christine Leroux, Ken Declerck, Katarzyna Szarc vel Szic, Karen Heyninck, Kris Laukens, Martin Bizet, Matthieu Defrance, Sarah Dedeurwaerder, Emilie Calonne, Francois Fuks, Guy Haegeman, Guido R M M Haenen, Aalt Bast, Antje R Weseler
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95527 (2014)
In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. The objective of the present study was to determine the im
Externí odkaz:
https://doaj.org/article/66dc8ff740ab4f338d19887c8d8c09cb
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114387 (2014)
The consumption of tomato products has been associated with a decreased risk for chronic inflammatory diseases. In this study, the anti-inflammatory potential of tomato ketchup was evaluated by studying the effect of tomato ketchup extracts and bioac
Externí odkaz:
https://doaj.org/article/4f6a00e5fbd84417bb48447ec6923ede
Autor:
Antje R Weseler, Erik J B Ruijters, Marie-José Drittij-Reijnders, Koen D Reesink, Guido R M M Haenen, Aalt Bast
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28460 (2011)
Cardiovascular diseases are expanding to a major social-economic burden in the Western World and undermine man's deep desire for healthy ageing. Epidemiological studies suggest that flavanol-rich foods (e.g. grapes, wine, chocolate) sustain cardiovas
Externí odkaz:
https://doaj.org/article/17feb4ed95e6407a8a3cab6d763ecf6c
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13880 (2010)
Antioxidants can scavenge highly reactive radicals. As a result the antioxidants are converted into oxidation products that might cause damage to vital cellular components. To prevent this damage, the human body possesses an intricate network of anti
Externí odkaz:
https://doaj.org/article/43a153fd9dc04f9e82b391bedc488ad8
Autor:
Guido R. M. M. Haenen
Publikováno v:
International Journal of Molecular Sciences, 24(7):6667. Multidisciplinary Digital Publishing Institute (MDPI)
‘Forever’ chemicals that unintendedly in the long run pollute the environment, climate change, COVID; life continuously faces all sorts of unforeseen challenges that are an inevitable side product of ‘progress’ [...]
Autor:
Mireille M J P E, Sthijns, Paul M, Schiffers, Ger M, Janssen, Kristien J A, Lemmens, Bart, Ides, Philippe, Vangrieken, Freek G, Bouwman, Edwin C, Mariman, Irina, Pader, Elias S J, Arnér, Katarina, Johansson, Aalt, Bast, Guido R M M, Haenen
Publikováno v:
Biochimica et biophysica acta. General subjects. 1861(5 Pt)
Rutin intake is associated with a reduced risk of cardiovascular disease (CVD). The exact mechanism by which rutin can protect against CVD development is still enigmatic. Since, rutin is a compound with a relatively short half-life, the direct antiox