Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Guido Bommer"'
1
Akademický článek
microRNA-155, induced by interleukin-1ß, represses the expression of microphthalmia-associated transcription factor (MITF-M) in melanoma cells.
Autor: Nathalie Arts, Stefania Cané, Marc Hennequart, Juliette Lamy, Guido Bommer, Benoît Van den Eynde, Etienne De Plaen
Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0122517 (2015)
Loss of expression of surface antigens represents a significant problem for cancer immunotherapy. Microphthalmia-associated transcription factor (MITF-M) regulates melanocyte fate by driving expression of many differentiation genes, whose protein pro
Externí odkaz: https://doaj.org/article/6d344dfb97f2435a8e08e4895c2687fc
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2
Akademický článek
GARP is regulated by miRNAs and controls latent TGF-β1 production by human regulatory T cells.
Autor: Emilie Gauthy, Julia Cuende, Julie Stockis, Caroline Huygens, Bernard Lethé, Jean-François Collet, Guido Bommer, Pierre G Coulie, Sophie Lucas
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e76186 (2013)
GARP is a transmembrane protein present on stimulated human regulatory T lymphocytes (Tregs), but not on other T lymphocytes (Th cells). It presents the latent form of TGF-β1 on the Treg surface. We report here that GARP favors the cleavage of the p
Externí odkaz: https://doaj.org/article/45aae26d779c4cc5bea07cfe174b69d2
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4
Data from Peroxisome Proliferator-Activated Receptor-γ Activation Inhibits Tumor Metastasis by Antagonizing Smad3-Mediated Epithelial-Mesenchymal Transition
Autor: Venkateshwar G. Keshamouni, Theodore J. Standiford, Jun Chen, Guido Bommer, Venkata R. Narala, Himabindu Kurapati, Ajaya Kumar Reka
Epithelial-mesenchymal transition (EMT) was shown to confer tumor cells with abilities essential for metastasis, including migratory phenotype, invasiveness, resistance to apoptosis, evading immune surveillance, and tumor stem cell traits. Therefore,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4497336e2a5889b88e47638a0ae00bbe
https://doi.org/10.1158/1535-7163.c.6531692.v1
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8
Human cytosolic transaminases: side activities and patterns of discrimination towards physiologically available alternative substrates
Autor: Francesco Caligiore, Erika Zangelmi, Carola Vetro, Takfarinas Kentache, Joseph P. Dewulf, Maria Veiga-da-Cunha, Emile Van Schaftingen, Guido Bommer, Alessio Peracchi
Publikováno v: Cellular and Molecular Life Sciences, Vol. 79, no.8, p. 421 (2022)
Transaminases play key roles in central metabolism, transferring the amino group from a donor substrate to an acceptor. These enzymes can often act, with low efficiency, on compounds different from the preferred substrates. To understand what might h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b88160474d82eb1fc5b5717136cb6a
https://pubmed.ncbi.nlm.nih.gov/35834009
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9
Duodenal CD8+ T resident memory cell apoptosis contributes to gut barrier dysfunction and microbial translocation in early alcohol-associated liver disease in humans
Autor: Luca Maccioni, Axelle Loriot, Joseph Dewulf, Guido Bommer, Yves Horsmans, Nicolas Lanthier, Isabelle Leclercq, Bernd Schnabl, Peter Stärkel
Publikováno v: Alimentary pharmacology & therapeutics, Vol. 56, no.6, p. 1055-1070 (2022)
Intestinal T cells are key in gut barrier function. Their role in early stages of alcohol-associated liver disease (ALD) remain unknown. To explore the links between intestinal T cells, microbial translocation and ALD METHODS: Patients with alcohol u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312402bf9f38d2bef3a279140a8c804e
https://hdl.handle.net/2078.1/269016
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10
Brief O
Autor: Tom, Darius, Martial, Vergauwen, Thomas, Smith, Isabelle, Gerin, Virginie, Joris, Matteo, Mueller, Selda, Aydin, Xavier, Muller, Andrea, Schlegel, Jay, Nath, Christian, Ludwig, Chantal, Dessy, Marie-Christine, Many, Guido, Bommer, Philipp, Dutkowski, Pierre, Gianello, Michel, Mourad
Publikováno v: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsREFERENCES. 20(8)
With oxygenation proposed as a resuscitative measure during hypothermic models of preservation, the aim of this study was to evaluate the optimal start time of oxygenation during continuous hypothermic machine perfusion (HMP). In this porcine ischemi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ba9c60c0ecd76458b57668791932bc0
https://pubmed.ncbi.nlm.nih.gov/32012434
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