Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Guido, Frosina"'
Autor:
Guido Frosina, Claudia Casella, Antonella Puppo, Enza Marani, Dalila Campanella, Luca Boni, Vincenzo Fontana
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract We present an updated analysis on the incidence of primary brain tumors in the Metropolitan Area of Genova, the capital of the northwestern Italian region Liguria. The number of cases and incidence rates for all malignant brain tumors, gliob
Externí odkaz:
https://doaj.org/article/25d7873fa53441c18884884175aa603c
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-6 (2019)
Abstract Doxycycline (DXC) is a tetracycline antibiotic which has been proposed as a breast cancer radiosensitizer by specifically reducing the expression of the DNA repair enzyme DNA PK in breast cancer initiating cells. Since DXC presents favorable
Externí odkaz:
https://doaj.org/article/b7ed20fe41b44d07a5c7199b29ad028b
Autor:
Guido Frosina
Publikováno v:
Strahlentherapie und Onkologie. 199:1-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db462da9457cf7292143ea5e78f46b91
https://doi.org/10.1007/s00066-022-02020-2
https://doi.org/10.1007/s00066-022-02020-2
Autor:
Guido Frosina
Publikováno v:
Journal of Neuroscience Research. 100:933-946
Ionizing radiation is a mainstay of high-grade glioma therapy. The current standard radiotherapeutic schedule involves a total 60 Gy split in 2.0 Gy fractions delivered on weekdays for six weeks. Thereafter, almost invariably the tumor relapses and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ef756c420c8c5c63d21ae49e4554eb
https://doi.org/10.1002/jnr.25030
https://doi.org/10.1002/jnr.25030
Autor:
Alessandra Rosa, Vincenzo Fontana, Giacomo Garibotto, Daniela Verzola, Stefano Vagge, Antonio Daga, Simona Pigozzi, Gabriele Gaggero, Guido Frosina
Publikováno v:
Journal of Neuroscience Research. 99:3182-3203
High-grade gliomas (HGGs; WHO grades III and IV) are invariably lethal brain tumors. Low-dose hyper-radiosensitivity (HRS) of HGG is a well-established phenomenon in vitro. However, possibly linked to the unavailability of accurate animal models of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b766039d297b0e9acd5a798751263e4
https://doi.org/10.1002/jnr.24929
https://doi.org/10.1002/jnr.24929
Autor:
Guido Frosina
Publikováno v:
International Journal of Molecular Sciences. 24:6375
High-grade gliomas (World Health Organization grades III and IV) are the most frequent and fatal brain tumors, with median overall survivals of 24–72 and 14–16 months, respectively. We reviewed the progress in the diagnosis and prognosis of high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f2013b1ddad2e2b702a287a5baa7c48
https://doi.org/10.3390/ijms24076375
https://doi.org/10.3390/ijms24076375
Autor:
Richard E. Kast, Nicolas Skuli, Iacopo Sardi, Felix Capanni, Martin Hessling, Guido Frosina, Anton P. Kast, Georg Karpel-Massler, Marc-Eric Halatsch
Publikováno v:
Brain Sciences, Vol 8, Iss 12, p 203 (2018)
The CAALA (Complex Augmentation of ALA) regimen was developed with the goal of redressing some of the weaknesses of 5-aminolevulinic acid (5-ALA) use in glioblastoma treatment as it now stands. 5-ALA is approved for use prior to glioblastoma surgery
Externí odkaz:
https://doaj.org/article/c5c4fcd90cbc48afa9dd842d36b4d774
Autor:
Guido Frosina
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8942, p 8942 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Albeit the effort to develop targeted therapies for patients with high-grade gliomas (WHO grades III and IV) is evidenced by hundreds of current clinical trials, radiation remains one of the few effective therapeutic options for them. This review art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337df758402986573206dc32d51e3e77
https://www.mdpi.com/1422-0067/22/16/8942
https://www.mdpi.com/1422-0067/22/16/8942
Autor:
Mara Foresta, Alberto Izzotti, Sebastiano La Maestra, Rosanna Micale, Alessandro Poggi, Donatella Vecchio, Guido Frosina
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87984 (2014)
Cigarette smoke (CS) is associated to a number of pathologies including lung cancer. Its mutagenic and carcinogenic effects are partially linked to the presence of reactive oxygen species and polycyclic aromatic hydrocarbons (PAH) inducing DNA damage
Externí odkaz:
https://doaj.org/article/5f5b8431612e4e4fba2622437b5c7e22
Autor:
Guido Frosina, Antonio Daga, Daniela Marubbi, Aldo Profumo, Jean Louis Ravetti, Diana Marcello
Publikováno v:
Radiation Oncology, Vol 13, Iss 1, Pp 1-7 (2018)
Radiation Oncology (London, England)
Radiation Oncology (London, England)
Ataxia Telangiectasia and Rad3 related protein (ATR) is a central mediator of the response to DNA damage that may cause the quiescent resistance of cancer initiating cells to genotoxic radiotherapy. NVP-BEZ235 is a dual PI3K/mTOR inhibitor that also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa585d0da2bdaa5e4d1a3fd6fb86867b
http://link.springer.com/article/10.1186/s13014-018-1020-3
http://link.springer.com/article/10.1186/s13014-018-1020-3