Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Guibin Lin"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 650-666 (2023)
The creation of safe and effective vaccines that induce potent cellular and humoral immune responses against SARS-CoV-2 is urgently needed to end the global COVID-19 epidemic. Here, we developed an alphavirus-derived self-replicating RNA (repRNA)-bas
Externí odkaz:
https://doaj.org/article/8939241ba77647d383d6af0ef01aee67
Publikováno v:
Nanomaterials, Vol 12, Iss 22, p 4052 (2022)
In order to solve the problems of rubropunctatin insoluble in water and its low bioavailability, and explore the synthesis method of green silver nanoparticles, rubropunctatin was used as reducing agent and blocking agent, rubropunctatin-functionaliz
Externí odkaz:
https://doaj.org/article/8e1755cf931f4a368adc918a0b2a064b
Autor:
Ke Jiang, Cuiping Song, Lingkai Kong, Lulu Hu, Guibin Lin, Tian Ye, Gang Yao, Yupeng Wang, Haibo Chen, Wei Cheng, Martin P. Barr, Quentin Liu, Guirong Zhang, Chan Ding, Songshu Meng
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Anaplastic thyroid cancer (ATC) is one of the most aggressive of all solid tumors for which no effective therapies are currently available. Oncolytic Newcastle disease virus (NDV) has shown the potential to induce oncolytic cell d
Externí odkaz:
https://doaj.org/article/4f253ead1fe544ea860254a8f4f7662e
Autor:
Min Liu, Ke Jiang, Guibin Lin, Peng Liu, Yumei Yan, Tian Ye, Gang Yao, Martin P. Barr, Dapeng Liang, Yang Wang, Peng Gong, Songshu Meng, Haozhe Piao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-17 (2018)
Abstract Background Aberrant activation of β-catenin and Yes-associated protein (YAP) signaling pathways has been associated with hepatocellular carcinoma (HCC) progression. The LIM domain protein Ajuba regulates β-catenin and YAP signaling and is
Externí odkaz:
https://doaj.org/article/02f78c6471d44c7aba6c7327a036c477
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Matrine, an alkaloid compound isolated from the medicinal plant Sophora flavescens, inhibits many types of cancer proliferation. However, the precise mechanism of the matrine antihuman chronic myeloid leukemia remains unclear. In this study, we showe
Externí odkaz:
https://doaj.org/article/95e18124705248bba518e73631572a80
Publikováno v:
Acta Biomaterialia. 161:213-225
Publikováno v:
Nano Research. 15:9057-9072
Autor:
Yuan Zhang, Guibin Lin
Self-replicating RNA (repRNA) derived from venezuelan equine encephalitis (VEE) virus is a promising platform for gene therapy and confers prolonged gene expression due to its self-replicating capability, but repRNA suffers from a suboptimal transgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd9b0890db94dbf2a5e4cd76cbe4cf0
https://doi.org/10.21203/rs.3.rs-2117118/v1
https://doi.org/10.21203/rs.3.rs-2117118/v1
Autor:
Lingdi Ma, Jian Wang, Lu-Bo Yang, Wang-Jing Zhong, Qiong-di Chen, Wei-Qiang Li, Jialin Cao, Guibin Lin
Publikováno v:
Chinese journal of integrative medicine. 27(9)
To study the mechanism of the anti-tumor effect of Morinda citrifolia (noni). The influences of noni juice on cell proliferation, apoptosis, invasion, migration and the activity of AKT/nuclear factor- κ B (NF- κ B) signaling pathway in A549 human l
Publikováno v:
Oncotarget
The BCR/ABL fusion gene and its downstream signaling pathways such as Ras/Raf/MAPK, JAK/STAT3, and PI3K/AKT pathways play important roles in malignant transformation of leukemia, especially chronic myelogenous leukemia (CML). Our previous study showe