Výsledky vyhledávání - "Guianfranco Mazzei"

Akademický článek

Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Autor: Erika Castillo, Julio Leon, Guianfranco Mazzei, Nona Abolhassani, Naoki Haruyama, Takashi Saito, Takaomi Saido, Masaaki Hokama, Toru Iwaki, Tomoyuki Ohara, Toshiharu Ninomiya, Yutaka Kiyohara, Kunihiko Sakumi, Frank M. LaFerla, Yusaku Nakabeppu

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)

Externí odkaz: https://doaj.org/article/f572c095786543faae8cc1b0521d89af

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Deficiency of MTH1 and/or OGG1 increases the accumulation of 8-oxoguanine in the brain of the AppNL-G-F/NL-G-F knock-in mouse model of Alzheimer’s disease, accompanied by accelerated microgliosis and reduced anxiety-like behavior

Autor: Takaomi C. Saido, Takashi Saito, Nona Abolhassani, Yusaku Nakabeppu, Y Mizuno, Jun-ichi Kira, Ryo Yamasaki, Guianfranco Mazzei

Publikováno v: Neuroscience Research. 177:118-134

Oxidative stress is a major risk factor for Alzheimer's disease (AD). Among various oxidized molecules, the marked accumulation of an oxidized form of guanine, 8-oxo-7,8-dihydroguanine (8-oxoG), is observed in the AD brain. 8-oxo-2´-deoxyguanosine t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ebf864f4f0590ee411079f184c34ef8
https://doi.org/10.1016/j.neures.2021.11.009

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MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer’s Disease

Autor: Yuri Mizuno, Nona Abolhassani, Guianfranco Mazzei, Kunihiko Sakumi, Takashi Saito, Takaomi C. Saido, Toshiharu Ninomiya, Toru Iwaki, Ryo Yamasaki, Jun-ichi Kira, Yusaku Nakabeppu

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)

Oxidative stress is a major risk factor for Alzheimer’s disease (AD), which is characterized by brain atrophy, amyloid plaques, neurofibrillary tangles, and loss of neurons. 8-Oxoguanine, a major oxidatively generated nucleobase highly accumulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930e6c0b3136325a61a441259ead52a4
https://doi.org/10.1155/2021/8635088

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Corrigendum to 'MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer’s Disease'

Autor: Yuri Mizuno, Nona Abolhassani, Guianfranco Mazzei, Kunihiko Sakumi, Takashi Saito, Takaomi C. Saido, Toshiharu Ninomiya, Toru Iwaki, Ryo Yamasaki, Jun-ichi Kira, Yusaku Nakabeppu

Publikováno v: Oxidative Medicine and Cellular Longevity. 2023:1-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37ae185b648e87766719c7e1ebea431d
https://doi.org/10.1155/2023/9794081

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A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App NL−F/NL−F knock‐in mouse model

Autor: Takaomi C. Saido, Ryohei Ikegami, Yusaku Nakabeppu, Takashi Saito, Naoki Haruyama, Kunihiko Sakumi, Nona Abolhassani, Guianfranco Mazzei

Publikováno v: Aging Cell

Insulin resistance and diabetes mellitus are major risk factors for Alzheimer's disease (AD), and studies with transgenic mouse models of AD have provided supportive evidence with some controversies. To overcome potential artifacts derived from trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58edff2e1a3efc4f7e30e7345ce1f11
http://europepmc.org/articles/PMC8373331

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Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Autor: Toru Iwaki, Masaaki Hokama, Yusaku Nakabeppu, Guianfranco Mazzei, Takashi Saito, Erika Castillo, Takaomi C. Saido, Toshiharu Ninomiya, Yutaka Kiyohara, Kunihiko Sakumi, Naoki Haruyama, Julio Leon, Frank M. LaFerla, Tomoyuki Ohara, Nona Abolhassani

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906a95b13338d61c77373ff74d470792
https://doaj.org/article/f572c095786543faae8cc1b0521d89af

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Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Autor: Yutaka Kiyohara, Guianfranco Mazzei, Tomoyuki Ohara, Frank M. LaFerla, Toshiharu Ninomiya, Yusaku Nakabeppu, Takashi Saito, Kunihiko Sakumi, Naoki Haruyama, Julio Leon, Nona Abolhassani, Erika Castillo, Toru Iwaki, Takaomi C. Saido, Masaaki Hokama

Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)

Alzheimer’s disease (AD) is the most common form of dementia, characterized by accumulation of amyloid β (Aβ) and neurofibrillary tangles. Oxidative stress and inflammation are considered to play an important role in the development and progressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4567b1b663c6271a5be4a7c9ff0fa4c
https://pubmed.ncbi.nlm.nih.gov/34504282

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