Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Gui-Rong Li"'
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Myocarditis refers to an autoimmune inflammatory response of the myocardium with characterization of self-reactive CD4+ T cell activation, which lacks effective treatment and has a poor prognosis. Acacetin is a natural flavonoid p
Externí odkaz:
https://doaj.org/article/d06c0a647fb947a6a3a39712f9f2d7bb
Autor:
Liang Mao, Yun-Da Li, Ruo-Lan Chen, Gang Li, Xiao-Xia Zhou, Fei Song, Chan Wu, Yu Hu, Yi-Xiang Hong, Xitong Dang, Gui-Rong Li, Yan Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Exosomes of human cardiosphere-derived cells (CDCs) are very promising for treating cardiovascular disorders. However, the current challenge is inconvenient delivery methods of exosomes for clinical application. The present study aims to exp
Externí odkaz:
https://doaj.org/article/a7d5fd3eaa9442c286ceedb7755cdf52
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
GRAPHICAL ABSTRACT
Externí odkaz:
https://doaj.org/article/5cff72b6ebdd47e0af26702d54463336
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The strategy of decreasing atherosclerotic cardiovascular disorder is imperative for reducing premature death and improving quality of life in patients with diabetes mellitus. The aim of this study was to investigate whether the natural flavone acace
Externí odkaz:
https://doaj.org/article/6c8f4b5e26574bb8885bb60d4c1aa7de
Autor:
José M Di Diego, Bence Patocskai, Hector Barajas-Martinez, Virág Borbáth, Michael J Ackerman, Alexander Burashnikov, Jérôme Clatot, Gui-Rong Li, Victoria M Robinson, Dan Hu, Charles Antzelevitch
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242747 (2020)
BackgroundJ wave syndromes (JWS), including Brugada (BrS) and early repolarization syndromes (ERS), are associated with increased risk for life-threatening ventricular arrhythmias. Pharmacologic approaches to therapy are currently very limited. Here,
Externí odkaz:
https://doaj.org/article/3cb25873eea6466eadaeb09bad7cd916
Autor:
Wei-Yin Wu, Yun-Da Li, Yu-Kai Cui, Chan Wu, Yi-Xiang Hong, Gang Li, Yao Wu, Ling-Jun Jie, Yan Wang, Gui-Rong Li
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The present study investigates the potential signal pathway of acacetin in cardioprotection against ischemia/reperfusion injury using an in vitro hypoxia/reoxygenation model in primary cultured neonatal rat cardiomyocytes and H9C2 cardiomyoblasts. It
Externí odkaz:
https://doaj.org/article/87088f25ed084a4ba07897bd497c5399
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The natural flavone acacetin inhibits several voltage-gated potassium currents in atrial myocytes, and has anti-atrial fibrillation (AF) effect in experimental AF models. The present study investigates whether acacetin inhibits the Ca2+-activated pot
Externí odkaz:
https://doaj.org/article/4d5c085ac3254f2f9490651152d30ccf
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138581 (2015)
Our previous study demonstrated that a large-conductance Ca2+-activated K+ current (BKCa), a voltage-gated TTX-sensitive sodium current (INa.TTX), and an inward rectifier K+ current (IKir) were heterogeneously present in most of human cardiac c-kit+
Externí odkaz:
https://doaj.org/article/fcb433bbd6e146fab8e5852306c63299
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0057864.].
Externí odkaz:
https://doaj.org/article/3a0b2356d4ca411bb543ed741d12566e
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79952 (2013)
Cholesterol is one of the major lipid components of the plasma membrane in mammalian cells and is involved in the regulation of a number of ion channels. The present study investigates how large conductance Ca(2+)-activated K(+) (BK) channels are reg
Externí odkaz:
https://doaj.org/article/3ce7195a92084635b11a5f18798e2ca4