Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Gui-Ling Tian"'
Publikováno v:
Chinese Journal of Chemistry. 20:1354-1357
A series of dipeptide derivatives containing non-coded amino acids, N-Boc-4-X-Phe-Ala-NHNHPh (X = Cl, Br, I, NO2), were synthesized by using thermoase in organic solvents. The physical data were consistent with the same samples prepared by 3-(diethox
Publikováno v:
Chinese Journal of Chemistry. 21:801-804
3-(Diethoxyphosphoryloxy)-1, 2, 3-benzotriazin-4(3H)-one (DEPBT) was an organophosphorus coupling reagent developed by our group. It was an effective coupling reagent for the synthesis of protected peptides containing Tyr, Ser and Thr with unprotecte
Publikováno v:
Chinese Journal of Chemistry. 21:864-870
Thioester method for the synthesis of cyclopeptides is improved by using Pac (Pac = phenacyl, CH2COC6H5) ester as a protecting group of 3-mercaptopropionic acid. The Pac group is easy to be removed from C-terminal with zinc in acetic acid. The protec
Publikováno v:
The Journal of Peptide Research. 52:300-304
The activity of enzymes to form a peptide bond in organic solvent was greatly influenced by observed pH and water content. The precursors of two sweeteners, P-Asp-Xaa-OR (P = Z or For, Xaa-OR = Phe-OMe or Ala-OcHex), were synthesized by enzyme, and t
Publikováno v:
The Journal of Peptide Research. 65:143-148
In order to extend the use of proteases to organic synthesis and seek the rules of enzymatic reactions in organic media, we focused on unnatural substrates for proteases to form amide bonds. In this paper, the study of unnatural substrates containing
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 37:26-29
The peptide bond formation of N -protected non-coded amino acids having different structures as acyl donor substrates that is catalyzed by thermoase in organic media was investigated. In these reactions, N -protected l -α-non-coded amino acids, incl
Autor:
Wai-Sum Lau, Yun-Hua Ye, Gui-Ling Tian, Robbie Chan, Man Sau Wong, Guo-Wen Xing, Kin-Sing Lee, Aixin Yan
Publikováno v:
Tetrahedron. 61:5933-5941
A series of N -protected amino acid-estradiol derivative conjugates have been synthesized by coupling of 17β-aminoestra-1,3,5 (10)-trien-3-ol ( 1 ) or 17β-hydrazonoestra-1,3,5 (10)-trien-3-ol ( 2 ) with different amino acids via the catalysis of su
Publikováno v:
International Journal of Peptide Research and Therapeutics. 10:571-579
Our recent studies on the synthetic methodology of head to tail cyclization of linear peptides are summarized in this paper. Ten cyclopeptides including six cyclopentapeptides as candidates of LHRH antagonists, two cyclopentapeptides, and two cyclohe
Publikováno v:
The Journal of Peptide Research. 60:95-103
Three cyclic peptides – cyclo(GlyAlaTyrLeuAla), cyclo(GlyProTyrLeuAla) and cyclo(GlyTyrGlyGlyProPhePro) – isolated and identified from medicinal herbs were chosen as model cyclic peptides to study the influence of the linear precursors and coupli
Publikováno v:
Synthetic Communications. 32:473-480
A series of N-protected peptide alcohols and one N-glycopeptide derivative were synthesized using DEPBT. We showed that the carboxyl group selectively reacted with amino group of the amino component in the presence of unprotected hydroxy groups.