Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gui-Lin Jin"'
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Koumine, an indole alkaloid, is a major bioactive component of Gelsemium elegans. Previous studies have demonstrated that koumine has noticeable anti-inflammatory and analgesic effects in inflammatory and neuropathic pain (NP) models, but the mechani
Externí odkaz:
https://doaj.org/article/fd02c957a7fa42bab05d118b24e28be0
Autor:
Gui-Lin Jin, Sai-Di He, Shao-Mei Lin, Li-Mian Hong, Wan-Qing Chen, Ying Xu, Jian Yang, Su-Ping Li, Chang-Xi Yu
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Despite decades of studies, the currently available drugs largely fail to control neuropathic pain. Koumine—an alkaloidal constituent derived from the medicinal plant Gelsemium elegans Benth.—has been shown to possess analgesic and anti-inflammat
Externí odkaz:
https://doaj.org/article/06eda0ff378b4662a067426d5eb1666f
Autor:
Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zhou
Publikováno v:
J Neurosci
Palmitoylation may be relevant to the processes of learning and memory, and even disorders, such as post-traumatic stress disorder and aging-related cognitive decline. However, underlying mechanisms of palmitoylation in these processes remain unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8e0c99fdfb10ca1197cb8343858913
https://doi.org/10.1523/jneurosci.1741-21.2022
https://doi.org/10.1523/jneurosci.1741-21.2022
Autor:
Gui-lin Jin, Hai-ping Liu, Ya-xin Huang, Qing-quan Zeng, Jin-xing Chen, Xiao-bing Lan, Zhi-ming Xin, Bo-jun Xiong, Rong-cai Yue, Chang-xi Yu
Publikováno v:
Phytomedicine. 108:154532
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437a73f80dcaef6d14cef76d16073337
https://doi.org/10.1016/j.phymed.2022.154532
https://doi.org/10.1016/j.phymed.2022.154532
Autor:
Gui-lin Jin, Hai-ping Liu, Ya-xin Huang, Qing-quan Zeng, Jin-xing Chen, Xiao-bing Lan, Zhi-ming Xin, Bo-jun Xiong, Rong-cai Yue, Chang-xi Yu
Publikováno v:
Phytomedicine. 107:154484
Translocator protein (TSPO) is an 18-kDa transmembrane protein found primarily in the mitochondrial outer membrane, and it is implicated in inflammatory responses, such as cytokine release. Koumine (KM) is an indole alkaloid extracted from Gelsemium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ab113e0ffc34192aeb097875a179b5
https://doi.org/10.1016/j.phymed.2022.154484
https://doi.org/10.1016/j.phymed.2022.154484
Autor:
Rong-cai Yue, Gui-Lin Jin, Li-Mian Hong, Hui-Hui Huang, Jian Yang, Yi Li, Ying Xu, Chang-Xi Yu, Zu-Cheng Shen, Yan-Ping Su, Bojun Xiong, Hai-Ping Liu
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 90
Background Diabetic neuropathic pain (DNP), a complication of diabetes, has serious impacts on human health. As the pathogenesis of DNP is very complex, clinical treatments for DNP is limited. Koumine (KM) is an active ingredient extracted from Gelse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9426d72333d3e38af2082768835ece28
https://pubmed.ncbi.nlm.nih.gov/34330066
https://pubmed.ncbi.nlm.nih.gov/34330066
Autor:
Chenxi Zhang, Hui-Hui Huang, Rong-cai Yue, Zhiyong Chu, Chang-Xi Yu, Shanshan Wei, Jian Yang, Li Su, Ying Xu, Ming Liu, Gui-Lin Jin
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2019 (2019)
Journal of Immunology Research, Vol 2019 (2019)
Nonalcoholic fatty liver disease (NAFLD) is the most common and important chronic liver disease all over the world. In the present study, we found that koumine, the main and active ingredient isolated from Gelsemium elegans, has the potential therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c303b3aaebb2a4333b11868dac49768
https://pubmed.ncbi.nlm.nih.gov/30915371
https://pubmed.ncbi.nlm.nih.gov/30915371
Publikováno v:
Journal of natural medicines. 73(1)
Gelsemium elegans Benth. is a toxic plant that has been used as an ancient Chinese herbal remedy for rheumatoid arthritis (RA) and nervous pain, spasticity, skin ulcers, and cancers. Koumine, one of its representative alkaloids, shows numerous promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca520433f79f2be8a098e7807bdedd3f
https://pubmed.ncbi.nlm.nih.gov/30054785
https://pubmed.ncbi.nlm.nih.gov/30054785
Autor:
Jian Yang, Ying Xu, Chang-Xi Yu, Gui-Lin Jin, Su‑Ping Li, Sai-di He, Li-Mian Hong, Shao-Mei Lin, Wan-Qing Chen
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Neural Plasticity
Neural Plasticity
Despite decades of studies, the currently available drugs largely fail to control neuropathic pain. Koumine—an alkaloidal constituent derived from the medicinal plantGelsemium elegansBenth.—has been shown to possess analgesic and anti-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9775a291ac08c962139a3d105724d2c
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Postoperative pain (POP) of various durations is a common complication of surgical procedures. POP is caused by nerve damage and inflammatory responses that are difficult to treat. The neuroinflammation-glia-steroid network is known to be important i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dd450741904c3c44a6848a67a8cdb5
https://doi.org/10.1038/s41598-017-14714-0
https://doi.org/10.1038/s41598-017-14714-0