Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Gui-Bo Sun"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115059- (2023)
Externí odkaz:
https://doaj.org/article/179ec376fb914e21b4fc39490f23dbba
Autor:
Ting Zhu, Bin-Yu Fang, Xiang-Bao Meng, Shu-Xia Zhang, Hong Wang, Ge Gao, Fei Liu, Yu Wu, Jin Hu, Gui-Bo Sun, Xiao-Bo Sun
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 195-205 (2022)
Context Folium Ginkgo extract and tetramethylpyrazine sodium chloride injection (Xingxiong injection) is a compound preparation commonly used for treating cerebral ischaemia/reperfusion injury in ischaemic stroke in China. However, its potential mech
Externí odkaz:
https://doaj.org/article/079e4fa867ed4d2cb87cba593ce6dc30
Autor:
Nan Li, Ying-Xia Xiong, Fan Ye, Bing Jin, Jin-Jia Wu, Miao-Miao Han, Tian Liu, Yi-Kai Fan, Cun-Yu Li, Jiu-Shi Liu, Ying-Hua Zhang, Gui-Bo Sun, Yun Zhang, Zheng-Qi Dong
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 895 (2023)
The activity of polysaccharides is usually related to molecular weight. The molecular weight of polysaccharides is critical to their immunological effect in cancer therapy. Herein, the Codonopsis polysaccharides of different molecular weights were is
Externí odkaz:
https://doaj.org/article/7fbc592567d44aa3b6d3db404e5fb7e2
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss , Pp 111693- (2021)
Nicotinamide phosphoribosyltransferase (NAMPT) maintains mitochondrial function and protects against cerebral ischemic injury by improving energy metabolism. Notoginsenoside R1 (R1), a unique constituent of Panax notoginseng, has been shown to promot
Externí odkaz:
https://doaj.org/article/a7abc0475f9d4d99abb32cc7c7f03a2e
Autor:
Yu Tian, Shan Wang, Hai Shang, Wen-Qian Wang, Bao-Qi Wang, Xi Zhang, Xu-Dong Xu, Gui-Bo Sun, Xiao-Bo Sun
Publikováno v:
Pharmaceutical Biology, Vol 57, Iss 1, Pp 133-139 (2019)
Context: Calenduloside E (CE), one of the primary natural products found in Aralia elata (Miq.) Seem. (Araliaceae), possesses prominent anti-apoptotic potential. A previous study found that one of the anti-apoptotic CE targets is heat shock protein 9
Externí odkaz:
https://doaj.org/article/db3189fdc83b4c6f846173bbf370c6c2
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 129, Iss , Pp 110470- (2020)
Ischemic stroke is a syndrome of severe neurological responses that cause neuronal death, damage to the neurovascular unit and inflammation. Notoginsenoside R1 (NG-R1) is a neuroprotective drug that is commonly used to treat neurodegenerative and cer
Externí odkaz:
https://doaj.org/article/68577d1be1d04841924338b8a678a3c0
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 5, Pp 1957-1969 (2017)
Background/Aims: This study aimed to investigate whether Salvianolic acid A (Sal A) conferred cardiac protection against Arsenic trioxide (ATO)-induced cardiotoxicity in H9c2 cells by inhibiting MAPK pathways activation. Methods: H9c2 cardiac cells w
Externí odkaz:
https://doaj.org/article/e8d770c9d04c46f490d2f25d9bc86077
Autor:
Zi-Ru Dai, Jing Ning, Gui-Bo Sun, Ping Wang, Feng Zhang, Hong-Ying Ma, Li-Wei Zou, Jie Hou, Jing-Jing Wu, Guang-Bo Ge, Xiao-Bo Sun, Ling Yang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Bufotalin (BFT), one of the naturally occurring bufodienolides, has multiple pharmacological and toxicological effects including antitumor activity and cardiotoxicity. This study aimed to character the metabolic pathway(s) of BFT and to identify the
Externí odkaz:
https://doaj.org/article/eabee42cdb1a406ca7305c2343efafb9
Autor:
Jing-yi Zhang, Min Wang, Rui-ying Wang, Xiao Sun, Yu-yang Du, Jing-xue Ye, Gui-bo Sun, Xiao-bo Sun
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Arsenic trioxide (ATO) is used as a therapeutic agent in the treatment of acute promyelocytic leukemia (APL). The therapeutic use of arsenic is limited due to its severe cardiovascular side effects. The cardio-protective effect of salvianolic acid A
Externí odkaz:
https://doaj.org/article/35ad4fd1922f4891b92c4b58d1fd64ce
Autor:
Shan Wang, Yu Tian, Jing-Yi Zhang, Hui-Bo Xu, Ping Zhou, Min Wang, Sen-Bao Lu, Yun Luo, Gui-Bo Sun, Xu-Dong Xu, Xiao-Bo Sun
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Calenduloside E (CE), a natural triterpenoid compound isolated from Aralia elata, can protect against ox-LDL-induced human umbilical vein endothelial cell (HUVEC) injury in our previous reports. However, the exact targets and mechanisms of CE remain
Externí odkaz:
https://doaj.org/article/e1a7b5722d1b41da87fbf2d92662c869