Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gui Lan Yao"'
Publikováno v:
Neuron. 41:229-241
The elaboration of dendrites is fundamental to the establishment of neuronal polarity and connectivity, but the mechanisms that underlie dendritic morphogenesis are poorly understood. We found that the genetic knockdown of the transcription factor Ne
Autor:
Antonio Riccio, Svetlana Gapon, David E. Clapham, Kiersten S. Smith, Yan Li, Uwe Rudolph, Gui Lan Yao, Evgeny Tsvetkov, Elif Engin, Vadim Y. Bolshakov
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(10)
Transient receptor potential (TRP) channels are abundant in the brain where they regulate transmission of sensory signals. The expression patterns of different TRPC subunits (TRPC1, 4, and 5) are consistent with their potential role in fear-related b
Autor:
Gui Lan Yao, Alexander M. Binshtok, Seog Bae Oh, Clifford J. Woolf, Michelino Puopolo, Bruce P. Bean
Publikováno v:
Journal of neurophysiology. 109(7)
QX-314 ( N-ethyl-lidocaine) is a cationic lidocaine derivative that blocks voltage-dependent sodium channels when applied internally to axons or neuronal cell bodies. Coapplication of external QX-314 with the transient receptor potential vanilloid 1
Publikováno v:
Brain Research. 599:333-337
It is well known that cutaneous pain causes c-fos gene expression in the dorsal horn neurons. The present study examined whether or not an itching sensation had the same effect on these neurons. In order to produce an itching sensation, cotton balls
Autor:
Evgeny Tsvetkov, Antonio Riccio, Svetlana Gapon, Kiersten S. Smith, Gui Lan Yao, Jisook Moon, Vadim Y. Bolshakov, Yan Li, Uwe Rudolph, Ashlee Van't Veer, Scott J. Rodig, Kwang-Soo Kim, David E. Clapham, Edward G. Meloni, William A. Carlezon
Publikováno v:
Cell. 137(4)
SUMMARY The transient receptor potential channel 5 (TRPC5) is predominantly expressed in the brain where it can form heterotetrameric complexes with TRPC1 and TRPC4 channel subunits. These excitatory, nonselective cationic channels are regulated by G
We studied acutely dissociated neurons from the dorsomedial (shell) region of the rat suprachiasmatic nucleus (SCN) with the aim of determining the ionic conductances that underlie spontaneous firing. Most isolated neurons were spontaneously active,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2849f008abd748d963fa18020b0497b1
https://europepmc.org/articles/PMC6729788/
https://europepmc.org/articles/PMC6729788/
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(13)
We characterized the properties and functional roles of voltage-dependent potassium channels in the dendrites of Purkinje neurons studied in rat cerebellar slices. Using outside-out patches formed ≤250 μm away from the soma, we found that depolari
Autor:
Larry I. Benowitz, Ilonna J. Rimm, David E. Goldberg, Paul MacDonald, Gui Lan Yao, Nina Irwin, Philip E. Stieg, Karina F. Meiri, Joseph R. Madsen
Publikováno v:
Experimental neurology. 154(2)
Tacrolimus (FK506), a widely used immunosuppressant drug, has neurite-promoting activity in cultured PC12 cells and peripheral neurons. The present study investigated whether tacrolimus affects the expression of the neuronal growth-associated protein
Publikováno v:
The European journal of neuroscience. 9(5)
Numerous studies have suggested that growth factors and cytokines play an important role in the survival of injured neurons and in neurite elongation. Therefore, intracellular signalling pathways activated by growth factors and cytokine receptors pla
Autor:
Gui Lan Yao, Hiroshi Kiyama
Publikováno v:
Brain research. Molecular brain research. 32(2)
Application of dexamethasone was found to induce an enhanced expression level of mRNA encoding the growth associated protein (GAP-43) after peripheral nerve injury. Following hypoglossal nerve axotomy, a dexamethasone releasing pellet (1.5 mg release